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Aytu BioPharma
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U.S.A
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373 Inverness Parkway, Suite 206 Englewood, CO 80112
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+1 855-298-8246

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Cotempla XR-ODT (methylphenidate extended-release orally disintegrating tablets) is a central nervous system (CNS) stimulant indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients 6 to 17 years of age.


Lead Product(s): Methylphenidate

Therapeutic Area: Psychiatry/Psychology Product Name: Cotempla

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 26, 2023

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Under the agreement, Medomie will commercialize Adzenys XR-ODT (amphetamine) and Cotempla XR-ODT (methylphenidate) in Israel and the Palestinian Authority.


Lead Product(s): Amphetamine

Therapeutic Area: Psychiatry/Psychology Product Name: Adzenys XR

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Medomie

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement July 31, 2023

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XR-ODT is FDA-Approved as Bioequivalent to Adderall XR is the only FDA-approved, extended-release, orally-disintegrating tablet formulation of amphetamine,indicated for the treatment of ADHD in patients six years and older.


Lead Product(s): Amphetamine

Therapeutic Area: Psychiatry/Psychology Product Name: Adzenys XR-ODT

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 05, 2022

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AR101 (enzastaurin) is an orally available investigational first-in-class small molecule, serine/threonine kinase inhibitor of the PKC beta, PI3K and AKT pathways.


Lead Product(s): Enzastaurin

Therapeutic Area: Genetic Disease Product Name: AR101

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 16, 2022

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The Company intends to use the net proceeds from the Offering for advancing the development of its pipeline assets, including for advancing the PREVEnt Trial evaluating AR101 for the treatment of vascular Ehlers-Danlos Syndrome (VEDS).


Lead Product(s): Enzastaurin

Therapeutic Area: Genetic Disease Product Name: AR101

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Canaccord Genuity

Deal Size: $10.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering August 15, 2022

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Acerus will acquire all remaining rights to Natesto in the United States from Aytu. Acerus will assume all product responsibilities associated with Natesto.


Lead Product(s): Testosterone

Therapeutic Area: Endocrinology Product Name: Natesto

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Acerus Pharmaceuticals

Deal Size: $7.5 million Upfront Cash: $7.5 million

Deal Type: Divestment April 01, 2021

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