
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Gepirone
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Sponsor : Lake Street Capital Markets
Deal Size : $16.6 million
Deal Type : Public Offering
Details : The Company intends to use the proceeds to exclusively commercialize Exxua (gepirone) extended-release tablets, a novel, branded, FDA-approved treatment for MDD in the United States.
Product Name : Exxua
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 09, 2025
Lead Product(s) : Gepirone
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Sponsor : Lake Street Capital Markets
Deal Size : $16.6 million
Deal Type : Public Offering

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Lead Product(s) : Gepirone
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Sponsor : Lake Street Capital Markets
Deal Size : $14.4 million
Deal Type : Public Offering
Aytu BioPharma Announces At the Market Pricing of $14.4 Million Upsized Public Offering
Details : The Company intends to use the proceeds to exclusively commercialize Exxua (gepirone) extended-release tablets, a novel, branded, FDA-approved treatment for MDD in the United States.
Product Name : Exxua
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 06, 2025
Lead Product(s) : Gepirone
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Sponsor : Lake Street Capital Markets
Deal Size : $14.4 million
Deal Type : Public Offering

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Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Sponsor : Lupin Pharma Canada
Deal Size : Undisclosed
Deal Type : Agreement
Aytu BioPharma Partners with Lupin Canada For ADHD Drug Commercialization
Details : The agreement aims for the distribution and supply for Aytu's Adzenys XR-ODT and Cotempla XR-ODT product lines for the treatment of ADHD in Canada.
Product Name : Adzenys XR-ODT
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 01, 2024
Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Sponsor : Lupin Pharma Canada
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Methylphenidate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cotempla XR-ODT (methylphenidate extended-release orally disintegrating tablets) is a central nervous system (CNS) stimulant indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients 6 to 17 years of age.
Product Name : Cotempla
Product Type : Controlled Substance
Upfront Cash : Inapplicable
October 26, 2023
Lead Product(s) : Methylphenidate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Recipient : Medomie
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the agreement, Medomie will commercialize Adzenys XR-ODT (amphetamine) and Cotempla XR-ODT (methylphenidate) in Israel and the Palestinian Authority.
Product Name : Adzenys XR
Product Type : Miscellaneous
Upfront Cash : Undisclosed
July 31, 2023
Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Recipient : Medomie
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : XR-ODT is FDA-Approved as Bioequivalent to Adderall XR is the only FDA-approved, extended-release, orally-disintegrating tablet formulation of amphetamine,indicated for the treatment of ADHD in patients six years and older.
Product Name : Adzenys XR-ODT
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 05, 2022
Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Enzastaurin
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aytu BioPharma Announces Issuance of Its First Patent for AR101/Enzastaurin
Details : AR101 (enzastaurin) is an orally available investigational first-in-class small molecule, serine/threonine kinase inhibitor of the PKC beta, PI3K and AKT pathways.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 16, 2022
Lead Product(s) : Enzastaurin
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Enzastaurin
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Canaccord Genuity
Deal Size : $10.0 million
Deal Type : Public Offering
Aytu BioPharma Announces Closing of $10.0 Million Registered Public Offering
Details : The Company intends to use the net proceeds from the Offering for advancing the development of its pipeline assets, including for advancing the PREVEnt Trial evaluating AR101 for the treatment of vascular Ehlers-Danlos Syndrome (VEDS).
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 15, 2022
Lead Product(s) : Enzastaurin
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Canaccord Genuity
Deal Size : $10.0 million
Deal Type : Public Offering

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Lead Product(s) : Enzastaurin
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Parexel
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Enzastaurin is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Ehlers-Danlos Syndrome, Type IV.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 19, 2022
Lead Product(s) : Enzastaurin
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Parexel
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Testosterone
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Acerus Pharmaceuticals
Deal Size : $7.5 million
Deal Type : Divestment
Aytu BioPharma Divests U.S. Rights to Natesto(R) to Acerus Pharma
Details : Acerus will acquire all remaining rights to Natesto in the United States from Aytu. Acerus will assume all product responsibilities associated with Natesto.
Product Name : Natesto
Product Type : Hormone
Upfront Cash : $7.5 million
April 01, 2021
Lead Product(s) : Testosterone
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Acerus Pharmaceuticals
Deal Size : $7.5 million
Deal Type : Divestment
