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    Looking for Direct Compression? Find Direct Compression Agents used in Tolvaptan to address drug delivery challenges on PharmaCompass.

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    Nippon provides high-performance, high-value-added cosmetic, pharmaceutical, and industrial raw materials.
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    01 SPI Pharma (6)

    02 Gangwal Healthcare (8)

    03 DFE Pharma (1)

    04 Microlex e.U (4)

    05 Seppic (2)

    06 Sigachi Industries (6)

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    01 Capsule (4)

    02 Granule / Pellet (1)

    03 Orodispersible Tablet (4)

    04 Tablet (18)

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    SPI Pharma

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    ADVANTOSE FS95

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    Applications:

    Advantose® FS95 is spray-dried fructose coprocessed with starch, is a highly compressible pharmaceutical excipient with chewable vitamin applications.

    Ingredient(s): Fructose, Starch

    Dosage Form: Orodispersible Tablet, Tablet

    Category: Chewable & Orodispersible Aids, Direct Compression, Taste Masking

    Route of Administration (Grade): Oral
    Pharmacopoeia Reference: NA

    Technical Specifications: NA

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    Gangwal Healthcare

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      PROBLEND®

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      Applications:

      ProBlend® is a co-processed excipient containing Silicified Microcrystalline Cellulose which is a glidant, lubricant, diluent, binder, and disintegrant. It is used in direct compression of solid oral dosage forms and MUPS formulations.

      Ingredient(s): Microcrystalline Cellulose

      Dosage Form: Capsule, Tablet

      Category: Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: USP-NF

      Technical Specifications: NA

      Gangwal Healthcare ProBlend®

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        LACTOSE DC

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        Applications:

        Lactose DC, a directly compressible lactose monohydrate co-processed excipient used in the production of solid dosage forms such as tablet, capsule, etc.

        Ingredient(s): Lactose Monohydrate

        Dosage Form: Capsule, Tablet

        Category: Co-Processed Excipients, Direct Compression

        Route of Administration (Grade): Oral
        Pharmacopoeia Reference: IP, USP

        Technical Specifications: NA

        Gangwal Healthcare Lactose DC

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        SPI Pharma

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        MS90

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        Applications:

        MS90 is a directly compressible magnesium hydroxide with starch used for chewable tablets due to its smooth mouthfeel and creamy texture.

        Ingredient(s): Magnesium Hydroxide Excipient, Starch

        Dosage Form: Orodispersible Tablet, Tablet

        Category: Chewable & Orodispersible Aids, Direct Compression, Taste Masking

        Route of Administration (Grade): Oral
        Pharmacopoeia Reference: NA

        Technical Specifications: PSD D50: 150-170, Taped Density: 0.80

        SPI Pharma MS90

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        Gangwal Healthcare

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          MICROLOSE® M25

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          Applications:

          Microlose® M25 is a co-processed DC excipient containing Lactose Monohydrate and Microcrystalline Cellulose that is used as a filler, binder, and disintegrant in oral solid dosage forms.

          Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

          Dosage Form: Capsule, Tablet

          Category: Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants

          Route of Administration (Grade): Oral
          Pharmacopoeia Reference: In-house

          Technical Specifications: NA

          Gangwal Healthcare Microlose® M25

          Iran Expo

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          SPI Pharma

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          CS90

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          Applications:

          CS90 is a directly compressible calcium carbonate with starch used for chewable tablets due to its smooth mouthfeel and creamy texture.

          Ingredient(s): Calcium Carbonate Excipient, Starch

          Dosage Form: Orodispersible Tablet, Tablet

          Category: Chewable & Orodispersible Aids, Direct Compression, Taste Masking

          Route of Administration (Grade): Oral
          Pharmacopoeia Reference: NA

          Technical Specifications: PSD D50: 150-175, Tapped Density: 0.85

          SPI Pharma CS90

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          Gangwal Healthcare

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            STARLOSE® P40

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            Applications:

            STARLOSE® is a co-processed directly compressible (DC) excipient consisting of Maize Starch and Lactose Monohydrate which is used as a diluent and binding agent in oral solids.

            Ingredient(s): Lactose Monohydrate, Maize Starch

            Dosage Form: Capsule, Tablet

            Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

            Route of Administration (Grade): Oral
            Pharmacopoeia Reference: IP, EP, USP-NF

            Technical Specifications: NA

            Gangwal Healthcare STARLOSE® P40

            Iran Expo

            Not Confirmed

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            DFE Pharma

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            PHARMACEL 102

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            Applications:

            Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

            Ingredient(s): Microcrystalline Cellulose

            Dosage Form: Tablet

            Category: Direct Compression

            Route of Administration (Grade): Oral
            Pharmacopoeia Reference: Conforms to USP-NF, Ph.Eur., JP, IP

            Technical Specifications: Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

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            Sigachi Industries

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              ACECEL

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              Applications:

              AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.

              Ingredient(s): Microcrystalline Cellulose

              Dosage Form: Tablet

              Category: Direct Compression, Fillers, Diluents & Binders, Granulation

              Route of Administration (Grade): Oral
              Pharmacopoeia Reference: Not Available

              Technical Specifications: Not Available
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              Sigachi Industries

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                HICEL

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                Applications:

                HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.

                Ingredient(s): Microcrystalline Cellulose

                Dosage Form: Tablet

                Category: Direct Compression, Fillers, Diluents & Binders, Granulation

                Route of Administration (Grade): Oral
                Pharmacopoeia Reference: Not Available

                Technical Specifications: Not Available
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                Sigachi Industries

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                  HICEL HFE

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                  Applications:

                  HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

                  Ingredient(s): Mannitol, Microcrystalline Cellulose

                  Dosage Form: Orodispersible Tablet

                  Category: Direct Compression, Disintegrants & Superdisintegrants

                  Route of Administration (Grade): Oral
                  Pharmacopoeia Reference: Not Available

                  Technical Specifications: Not Available
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                    HICELLAC

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                    Applications:

                    HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

                    Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

                    Dosage Form: Tablet

                    Category: Direct Compression, Granulation

                    Route of Administration (Grade): Oral
                    Pharmacopoeia Reference: Not Available

                    Technical Specifications: Not Available
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                    Sigachi Industries

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                      HICEL SMCC

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                      Applications:

                      HiCel SMCC has unique combination which result in optimum compaction & superior flow properties.

                      Ingredient(s): Microcrystalline Cellulose, Silicon Dioxide

                      Dosage Form: Tablet

                      Category: Direct Compression, Fillers, Diluents & Binders, Lubricants & Glidants

                      Route of Administration (Grade): Oral
                      Pharmacopoeia Reference: Not Available

                      Technical Specifications: Not Available
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                      Microlex e.U

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                        MICROLEX® MCC 101

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                        Applications:

                        Tablets made from these granules are typically easily disintegrated using conventional super disintegrates even when hard tablets are compressed.

                        Ingredient(s): Microcrystalline Cellulose

                        Dosage Form: Tablet

                        Category: Direct Compression, Granulation

                        Route of Administration (Grade): Oral
                        Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                        Technical Specifications: Not Available
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                        Microlex e.U

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                          MICROLEX® MCC 102

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                          Applications:

                          The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

                          Ingredient(s): Microcrystalline Cellulose

                          Dosage Form: Tablet

                          Category: Direct Compression

                          Route of Administration (Grade): Oral
                          Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                          Technical Specifications: Not Available
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                          Microlex e.U

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                            MICROLEX® LCM 80.M

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                            Applications:

                            Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

                            Ingredient(s): Lactose Monohydrate

                            Dosage Form: Tablet

                            Category: Direct Compression, Granulation

                            Route of Administration (Grade): Oral
                            Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                            Technical Specifications: Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m
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                            Microlex e.U

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                              MICROLEX® LCM 120.S

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                              Applications:

                              It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

                              Ingredient(s): Lactose Monohydrate

                              Dosage Form: Tablet

                              Category: Direct Compression, Granulation

                              Route of Administration (Grade): Oral
                              Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                              Technical Specifications: Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s
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                              Sigachi Industries

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                                FILLERLAC

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                                Applications:

                                Lactose is widely used as a filler and diluent in tablets and capsules, and to a more limited extent in lyophilized products and infant formulas.

                                Ingredient(s): Lactose Monohydrate

                                Dosage Form: Tablet

                                Category: Direct Compression, Fillers, Diluents & Binders

                                Route of Administration (Grade): Oral and Parenteral
                                Pharmacopoeia Reference: Not Available

                                Technical Specifications: Not Available
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                                Seppic

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                                SEPISTAB ST 200

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                                Applications:

                                Capsule Filling, Direct Compression, Binding, Disintegration

                                Ingredient(s): Native & Pregelatinized Corn Starch

                                Dosage Form: Granule / Pellet, Tablet

                                Category: Direct Compression

                                Route of Administration (Grade): Oral
                                Pharmacopoeia Reference: Not Available

                                Technical Specifications: EXCiPACT
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