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    Looking for Direct Compression? Find Direct Compression Agents used in Apixaban to address drug delivery challenges on PharmaCompass.

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    Apixaban

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

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    01 2BASF

    02 2DFE Pharma

    03 5Microlex e.U

    04 1Prachin Chemical

    05 5Sigachi Industries

    06 2The Dow Chemical Company

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    PharmaCompass

    01

    Sigachi Industries

    ACECEL

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    APGA Annual Conference
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    02

    DFE Pharma

    PHARMACEL 102

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    DFE Pharma

    Germany
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Pharmacel 102

    Application : Direct Compression

    Excipient Details : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : PHARMACEL 102

    Applications : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., JP, IP

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Grade : Oral

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    03

    Prachin Chemical

    PARCROS

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    04

    Sigachi Industries

    HICEL

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    05

    DFE Pharma

    SUPERTAB 21AN

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    DFE Pharma

    Germany
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Supertab 21AN

    Application : Direct Compression

    Excipient Details : SuperTab® 11SD offers the best compactability of all grades of lactose, and it is well suited to direct compression applications. Due to the low moisture content, it is used in the formulations containing moisture sensitive drugs.

    Pharmacopoeia Ref : Conforms to Ph. Eur., Lactose ...

    Technical Specs : Density- Tapped density- 906 g/l, Bulk density- 722 g/l; Particle size- D10-15 ?m, D50- 170 ?m, D90- 340 ?m; Hausner ratio-1,25

    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : SUPERTAB 21AN

    Applications : SuperTab® 11SD offers the best compactability of all grades of lactose, and it is well suited to direct compression applications. Due to the low moisture content, it is used in the formulations containing moisture sensitive drugs.

    Pharmacopoeia Ref : Conforms to Ph. Eur., Lactose monograph / USP-NF, JP Anhydrous lactose monograph

    Technical Specs : Density- Tapped density- 906 g/l, Bulk density- 722 g/l; Particle size- D10-15 ?m, D50- 170 ?m, D90- 340 ?m; Hausner ratio-1,25

    Grade : Oral

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    06

    The Dow Chemical Company

    METHOCEL™

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    The Dow Chemical Company

    U.S.A
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    Dosage Form : Tablet, Capsule

    Grade :

    Brand Name : METHOCEL™

    Application : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Grade :

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    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Category : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Brand : METHOCEL™

    Applications : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Not Available

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    07

    Sigachi Industries

    HICEL SMCC

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    08

    BASF

    KOLLIPHOR SLS FINE

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    09

    Sigachi Industries

    HICELLAC

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    10

    Microlex e.U

    MICROLEX® MCC 101

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    11

    Microlex e.U

    MICROLEX® MCC 102

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® MCC 102

    Application : Direct Compression

    Excipient Details : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs :

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : MICROLEX® MCC 102

    Applications : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Not Available

    Grade : Oral

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    12

    Microlex e.U

    MICROLEX® LCM 80.M

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 80.m

    Application : Direct Compression, Granulation

    Excipient Details : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 80.M

    Applications : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Grade : Oral

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    13

    Microlex e.U

    MICROLEX® LCM 120.S

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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 120.s

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 120.S

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Grade : Oral

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    14

    Microlex e.U

    MICROLEX® LCA 60.M

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    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCA 60.m

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCA 120.m, Microlex® LCA 200.m

    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCA 60.M

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCA 120.m, Microlex® LCA 200.m

    Grade : Oral

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    15

    Sigachi Industries

    HICEL HFE

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