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    Looking for Direct Compression? Find Direct Compression Agents used in Apalutamide to address drug delivery challenges on PharmaCompass.

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    01 DKSH (2)

    02 Gangwal Healthcare (4)

    03 Aeon Procare (2)

    04 DFE Pharma (1)

    05 Microlex e.U (2)

    06 Prachin Chemical (1)

    07 Sigachi Industries (5)

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    DKSH

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    TALC

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    Applications:

    Talc is widely used as a dissolution retardant in the development of controlled release products. It is also used for direct compression and as a glidant in solid dosage forms such as tablets.

    Ingredient(s): Talc Excipient

    Dosage Form: Capsule, Tablet

    Category: Controlled & Modified Release, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders

    Route of Administration (Grade): Oral
    Pharmacopoeia Reference: Not Available

    Technical Specifications: Not Available

    Talc

    BioFIT 2023

    Not Confirmed

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    Gangwal Healthcare

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      PROBLEND®

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      Applications:

      ProBlend® is a co-processed excipient containing Silicified Microcrystalline Cellulose which is a glidant, lubricant, diluent, binder, and disintegrant. It is used in direct compression of solid oral dosage forms and MUPS formulations.

      Ingredient(s): Microcrystalline Cellulose

      Dosage Form: Capsule, Tablet

      Category: Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: USP-NF

      Technical Specifications: NA

      Gangwal Healthcare ProBlend®

      BioFIT 2023

      Not Confirmed

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      Gangwal Healthcare

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        MICROLOSE® M25

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        Applications:

        Microlose® M25 is a co-processed DC excipient containing Lactose Monohydrate and Microcrystalline Cellulose that is used as a filler, binder, and disintegrant in oral solid dosage forms.

        Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

        Dosage Form: Capsule, Tablet

        Category: Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants

        Route of Administration (Grade): Oral
        Pharmacopoeia Reference: In-house

        Technical Specifications: NA

        Gangwal Healthcare Microlose® M25

        BioFIT 2023

        Not Confirmed

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        Prachin Chemical

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          PARCROS

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          Applications:

          Croscarmellose sodium, a cellulose-based super disintegrant, provides excellent results in tablet disintegration. It is used in both wet granulation and direct compression.

          Ingredient(s): Croscarmellose Sodium

          Dosage Form: Tablet

          Category: Direct Compression, Disintegrants & Superdisintegrants, Granulation

          Route of Administration (Grade): Oral
          Pharmacopoeia Reference: IP/BP/USP/EP

          Technical Specifications: NA
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          Sigachi Industries

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            ACECEL

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            Applications:

            AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.

            Ingredient(s): Microcrystalline Cellulose

            Dosage Form: Tablet

            Category: Direct Compression, Fillers, Diluents & Binders, Granulation

            Route of Administration (Grade): Oral
            Pharmacopoeia Reference: Not Available

            Technical Specifications: Not Available
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            DFE Pharma

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            PHARMACEL 102

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            Applications:

            Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

            Ingredient(s): Microcrystalline Cellulose

            Dosage Form: Tablet

            Category: Direct Compression

            Route of Administration (Grade): Oral
            Pharmacopoeia Reference: Conforms to USP-NF, Ph.Eur., JP, IP

            Technical Specifications: Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

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            Aeon Procare

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              TALC

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              Applications:

              Talc is a widely used as a dissolution retardant in the development of controlled release products. Talc is also used as a lubricant in tablet formulations.

              Ingredient(s): Talc Excipient

              Dosage Form: Granule / Pellet, Tablet

              Category: Controlled & Modified Release, Lubricants & Glidants

              Route of Administration (Grade): Oral & Topical
              Pharmacopoeia Reference: Not Available

              Technical Specifications: Not Available
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              Sigachi Industries

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                HICEL

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                Applications:

                HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.

                Ingredient(s): Microcrystalline Cellulose

                Dosage Form: Tablet

                Category: Direct Compression, Fillers, Diluents & Binders, Granulation

                Route of Administration (Grade): Oral
                Pharmacopoeia Reference: Not Available

                Technical Specifications: Not Available
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                Sigachi Industries

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                  HICEL HFE

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                  Applications:

                  HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

                  Ingredient(s): Mannitol, Microcrystalline Cellulose

                  Dosage Form: Orodispersible Tablet

                  Category: Direct Compression, Disintegrants & Superdisintegrants

                  Route of Administration (Grade): Oral
                  Pharmacopoeia Reference: Not Available

                  Technical Specifications: Not Available
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                  Sigachi Industries

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                    HICELLAC

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                    Applications:

                    HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

                    Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

                    Dosage Form: Tablet

                    Category: Direct Compression, Granulation

                    Route of Administration (Grade): Oral
                    Pharmacopoeia Reference: Not Available

                    Technical Specifications: Not Available
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                    Sigachi Industries

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                      HICEL SMCC

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                      Applications:

                      HiCel SMCC has unique combination which result in optimum compaction & superior flow properties.

                      Ingredient(s): Microcrystalline Cellulose, Silicon Dioxide

                      Dosage Form: Tablet

                      Category: Direct Compression, Fillers, Diluents & Binders, Lubricants & Glidants

                      Route of Administration (Grade): Oral
                      Pharmacopoeia Reference: Not Available

                      Technical Specifications: Not Available
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                      Microlex e.U

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                        MICROLEX® MCC 101

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                        Applications:

                        Tablets made from these granules are typically easily disintegrated using conventional super disintegrates even when hard tablets are compressed.

                        Ingredient(s): Microcrystalline Cellulose

                        Dosage Form: Tablet

                        Category: Direct Compression, Granulation

                        Route of Administration (Grade): Oral
                        Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                        Technical Specifications: Not Available
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                        Microlex e.U

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                          MICROLEX® MCC 102

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                          Applications:

                          The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

                          Ingredient(s): Microcrystalline Cellulose

                          Dosage Form: Tablet

                          Category: Direct Compression

                          Route of Administration (Grade): Oral
                          Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE