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    List of all Manufacturers, Suppliers & Exporters of Ripretinib API listed on PharmaCompass with details of regulatory filings

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    Ripretinib

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    01 Dr. Reddy's Laboratories (1)

    02 Teva API (1)

    03 Beijing Sjar Technology Development (1)

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    Dr. Reddy's Laboratories

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    Teva API

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    Beijing Sjar Technology Development

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      Looking for 1442472-39-0 / Ripretinib API manufacturers, exporters & distributors?

      Ripretinib manufacturers, exporters & distributors 1

      79

      PharmaCompass offers a list of Ripretinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ripretinib manufacturer or Ripretinib supplier for your needs.

      Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ripretinib manufacturer or Ripretinib supplier.

      PharmaCompass also assists you with knowing the Ripretinib API Price utilized in the formulation of products. Ripretinib API Price is not always fixed or binding as the Ripretinib Price is obtained through a variety of data sources. The Ripretinib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

      API | Excipient name

      Ripretinib

      Synonyms

      1442472-39-0, Dcc-2618, N-{4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3- yl]-2-fluorophenyl}-n'-phenylurea, Urea, n-[4-bromo-5-[1-ethyl-1,2-dihydro-7-(methylamino)-2-oxo-1,6- naphthyridin-3-yl]-2-fluorophenyl]-n'-phenyl-39-0, Ripretinib free base, Ripretinib [usan]

      Cas Number

      1442472-39-0

      Unique Ingredient Identifier (UNII)

      9XW757O13D

      About Ripretinib

      Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) KIT and platelet-derived growth factor receptor alpha (PDGFR-alpha; PDGFRa), with potential antineoplastic activity. Upon oral administration, ripretinib targets and binds to both wild-type and mutant forms of KIT and PDGFRa specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. This abrogates KIT/PDGFRa-mediated tumor cell signaling and prevents proliferation in KIT/PDGFRa-driven cancers. DCC-2618 also inhibits several other kinases, including vascular endothelial growth factor receptor type 2 (VEGFR2; KDR), angiopoietin-1 receptor (TIE2; TEK), PDGFR-beta and macrophage colony-stimulating factor 1 receptor (FMS; CSF1R), thereby further inhibiting tumor cell growth. KIT and PDGFRa are tyrosine kinase receptors that are upregulated or mutated in a variety of cancer cell types; mutated forms play a key role in the regulation of tumor cell proliferation and resistance to chemotherapy.

      Ripretinib Manufacturers

      A Ripretinib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ripretinib, including repackagers and relabelers. The FDA regulates Ripretinib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ripretinib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

      click here to find a list of Ripretinib manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

      Ripretinib Suppliers

      A Ripretinib supplier is an individual or a company that provides Ripretinib active pharmaceutical ingredient (API) or Ripretinib finished formulations upon request. The Ripretinib suppliers may include Ripretinib API manufacturers, exporters, distributors and traders.

      click here to find a list of Ripretinib suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

      Ripretinib Manufacturers | Traders | Suppliers

      Ripretinib Manufacturers, Traders, Suppliers 1
      78

      We have 3 companies offering Ripretinib

      Get in contact with the supplier of your choice:

      1. Dr. Reddy's Laboratories
      2. Teva API
      3. Beijing Sjar Technology Development
      Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
      For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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