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List of Ripretinib NDC API suppliers/manufacturers & exporters

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01 Cambrex Charles City, Inc (4)

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01 Ripretinib (4)

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01 U.S.A (4)

URL Supplier Web Content
Ripretinib
POWDER (1kg/kg)
BULK INGREDIENT
59116-5333
2020-02-24
2024-12-31
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Ripretinib
POWDER (1kg/kg)
BULK INGREDIENT
59116-5332
2020-02-24
2024-12-31
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Ripretinib
POWDER (1kg/kg)
BULK INGREDIENT
59116-5331
2020-02-24
2024-12-31
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Ripretinib
POWDER (1kg/kg)
BULK INGREDIENT
59116-5330
2020-02-24
2024-12-31
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Looking for 1442472-39-0 / Ripretinib API manufacturers, exporters & distributors?

Ripretinib manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ripretinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ripretinib manufacturer or Ripretinib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ripretinib manufacturer or Ripretinib supplier.

PharmaCompass also assists you with knowing the Ripretinib API Price utilized in the formulation of products. Ripretinib API Price is not always fixed or binding as the Ripretinib Price is obtained through a variety of data sources. The Ripretinib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ripretinib

Synonyms

1442472-39-0, Dcc-2618, N-{4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3- yl]-2-fluorophenyl}-n'-phenylurea, Urea, n-[4-bromo-5-[1-ethyl-1,2-dihydro-7-(methylamino)-2-oxo-1,6- naphthyridin-3-yl]-2-fluorophenyl]-n'-phenyl-39-0, Ripretinib free base, Ripretinib [usan]

Cas Number

1442472-39-0

Unique Ingredient Identifier (UNII)

9XW757O13D

About Ripretinib

Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) KIT and platelet-derived growth factor receptor alpha (PDGFR-alpha; PDGFRa), with potential antineoplastic activity. Upon oral administration, ripretinib targets and binds to both wild-type and mutant forms of KIT and PDGFRa specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. This abrogates KIT/PDGFRa-mediated tumor cell signaling and prevents proliferation in KIT/PDGFRa-driven cancers. DCC-2618 also inhibits several other kinases, including vascular endothelial growth factor receptor type 2 (VEGFR2; KDR), angiopoietin-1 receptor (TIE2; TEK), PDGFR-beta and macrophage colony-stimulating factor 1 receptor (FMS; CSF1R), thereby further inhibiting tumor cell growth. KIT and PDGFRa are tyrosine kinase receptors that are upregulated or mutated in a variety of cancer cell types; mutated forms play a key role in the regulation of tumor cell proliferation and resistance to chemotherapy.

Ripretinib Manufacturers

A Ripretinib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ripretinib, including repackagers and relabelers. The FDA regulates Ripretinib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ripretinib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ripretinib manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ripretinib Suppliers

A Ripretinib supplier is an individual or a company that provides Ripretinib active pharmaceutical ingredient (API) or Ripretinib finished formulations upon request. The Ripretinib suppliers may include Ripretinib API manufacturers, exporters, distributors and traders.

click here to find a list of Ripretinib suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ripretinib NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ripretinib as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Ripretinib API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Ripretinib as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Ripretinib and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ripretinib NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Ripretinib suppliers with NDC on PharmaCompass.

Ripretinib Manufacturers | Traders | Suppliers

Ripretinib Manufacturers, Traders, Suppliers 1
40

We have 1 companies offering Ripretinib

Get in contact with the supplier of your choice:

  1. Cambrex Corporation
Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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