1. 2'-deoxy-2'-beta-fluoro-4'-azidocytidine
2. 4'-azido-2'-deoxy-2'-fluorocytidine
3. 4-amino-1-((2r,3r,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-5-((imino-l,5-azanylidene)amino)tetrahydrofuran-2-yl)pyrimidin-2-one
4. 4-amino-1-((2r,3s,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-5-((imino-l,5-azanylidene)amino)tetrahydrofuran-2-yl)pyrimidin-2-one
5. Ro-0622
1. Ro-0622
2. 1011529-10-4
3. 4-amino-1-((2r,3s,4r,5r)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1h)-one
4. 4-amino-1-[(2r,3s,4r,5r)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
5. Chembl519846
6. Fncro-0622
7. 4'-c-azido-2'-deoxy-2'-fluoro-beta-d-arabinocytidine
8. Schembl15866623
9. Dtxsid901027757
10. Glxc-25994
11. Hy-19314
12. Cs-0015081
13. A848947
14. 2(1h)-pyrimidinone, 4-amino-1-(4-c-azido-2-deoxy-2-fluoro-b-d-arabinofuranosyl)-
15. 4-amino-1-[(2r,3s,4r,5r)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
| Molecular Weight | 286.22 g/mol |
|---|---|
| Molecular Formula | C9H11FN6O4 |
| XLogP3 | -0.8 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 3 |
| Exact Mass | 286.08258102 g/mol |
| Monoisotopic Mass | 286.08258102 g/mol |
| Topological Polar Surface Area | 123 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 533 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 1 |
| Covalently Bonded Unit Count | 1 |
Azvudine is a nucleoside reverse transcriptase inhibitor that acts against HIV, HBV, and HCV. Some studies also show that it is able to modulate the expression of proteins like P-glycoprotein (P-gp), MRP2, and BCRP; in one instance, it was also able to increase the activity of P-gp. In 2020, the compound was tested in numerous clinical trials for the treatment of mild and common COVID-19.
