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Chemistry

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Also known as: 887148-69-8, Monepantel [inn], Aad1566, Chebi:78621, 82ma79vj33, N-(2-cyano-1-((2s)-5-cyano-2-(trifluoromethyl)phenoxy)propan-2-yl)-4-(trifluoromethylsulfanyl)benzamide
Molecular Formula
C20H13F6N3O2S
Molecular Weight
473.4  g/mol
InChI Key
WTERNLDOAPYGJD-SFHVURJKSA-N
FDA UNII
82MA79VJ33

Monepantel
1 2D Structure

Monepantel

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[(2S)-2-cyano-1-[5-cyano-2-(trifluoromethyl)phenoxy]propan-2-yl]-4-(trifluoromethylsulfanyl)benzamide
2.1.2 InChI
InChI=1S/C20H13F6N3O2S/c1-18(10-28,11-31-16-8-12(9-27)2-7-15(16)19(21,22)23)29-17(30)13-3-5-14(6-4-13)32-20(24,25)26/h2-8H,11H2,1H3,(H,29,30)/t18-/m0/s1
2.1.3 InChI Key
WTERNLDOAPYGJD-SFHVURJKSA-N
2.1.4 Canonical SMILES
CC(COC1=C(C=CC(=C1)C#N)C(F)(F)F)(C#N)NC(=O)C2=CC=C(C=C2)SC(F)(F)F
2.1.5 Isomeric SMILES
C[C@@](COC1=C(C=CC(=C1)C#N)C(F)(F)F)(C#N)NC(=O)C2=CC=C(C=C2)SC(F)(F)F
2.2 Other Identifiers
2.2.1 UNII
82MA79VJ33
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 887148-69-8

2. Monepantel [inn]

3. Aad1566

4. Chebi:78621

5. 82ma79vj33

6. N-(2-cyano-1-((2s)-5-cyano-2-(trifluoromethyl)phenoxy)propan-2-yl)-4-(trifluoromethylsulfanyl)benzamide

7. Zolvix

8. Benzamide, N-[(1s)-1-cyano-2-[5-cyano-2-(trifluoromethyl)phenoxy]-1-methylethyl]-4-[(trifluoromethyl)thio]-

9. N-[(2s)-2-cyano-1-[5-cyano-2-(trifluoromethyl)phenoxy]propan-2-yl]-4-(trifluoromethylsulfanyl)benzamide

10. Monepantelum

11. Unii-82ma79vj33

12. Benzamide, N-((1s)-1-cyano-2-(5-cyano-2-(trifluoromethyl)phenoxy)-1-methylethyl)-4-((trifluoromethyl)thio)-

13. Monepantel [mi]

14. Chembl256563

15. Schembl1547706

16. Zolvix Component Monepantel

17. Zinc29045455

18. Monepantel Component Of Zolvix

19. Cs-6054

20. Monepantel [ema Epar Veterinary]

21. Ncgc00522551-01

22. Hy-14774

23. A901727

24. Q27147876

25. Benzamide, N-[(1s)-1-cyano-2-[5-cyano-2-(trifluoromethyl)phenoxy]-1-methylethyl]-4-[(trifluoromethyl)thio]-;monepantel

26. N-[(1s)-1-cyano-2-(5-cyano-2-trifluoromethyl-phenoxy)-1-methyl-ethyl]-4-trifluoromethylsulfanyl-benzamide

27. N-{(2s)-2-cyano-1-[5-cyano-2-(trifluoromethyl)phenoxy]propan-2-yl}-4-[(trifluoromethyl)sulfanyl]benzamide

2.4 Create Date
2009-11-19
3 Chemical and Physical Properties
Molecular Weight 473.4 g/mol
Molecular Formula C20H13F6N3O2S
XLogP35.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Exact Mass473.06326681 g/mol
Monoisotopic Mass473.06326681 g/mol
Topological Polar Surface Area111 Ų
Heavy Atom Count32
Formal Charge0
Complexity763
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Zolvix oral solution is a broad spectrum anthelmintic for the treatment and control of gastro-intestinal nematode infections and associated diseases in sheep including lambs, hoggets, breeding rams and ewes.

Spectrum of activity includes fourth larvae and adults of:

- Haemonchus contortus*;

- Teladorsagia circumcincta*;

- Teladorsagia trifurcata*;

- Teladorsagia davtiani*;

- Trichostrongylus axei*;

- Trichostrongylus colubriformis;

- Trichostrongylus vitrinus;

- Cooperia curticei;

- Cooperia oncophora;

- Nematodirus battus;

- Nematodirus filicollis;

- Nematodirus spathiger;

- Chabertia ovina;

- Oesophagostomum venulosum.

* including inhibited larvae.

The veterinary medicinal product is effective against strains of these parasites resistant to (pro)benzimidazoles, levamisole, morantel, macrocyclic lactones and H. contortus strains resistant to salicylanilides.


5 Pharmacology and Biochemistry
5.1 ATC Code

QP52AX09


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Monepantel manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Monepantel API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Monepantel manufacturer or Monepantel supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Monepantel manufacturer or Monepantel supplier.

PharmaCompass also assists you with knowing the Monepantel API Price utilized in the formulation of products. Monepantel API Price is not always fixed or binding as the Monepantel Price is obtained through a variety of data sources. The Monepantel Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Monepantel

Synonyms

887148-69-8, Monepantel [inn], Aad1566, Chebi:78621, 82ma79vj33, N-(2-cyano-1-((2s)-5-cyano-2-(trifluoromethyl)phenoxy)propan-2-yl)-4-(trifluoromethylsulfanyl)benzamide

Cas Number

887148-69-8

Unique Ingredient Identifier (UNII)

82MA79VJ33

Monepantel Manufacturers

A Monepantel manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Monepantel, including repackagers and relabelers. The FDA regulates Monepantel manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Monepantel API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Monepantel Suppliers

A Monepantel supplier is an individual or a company that provides Monepantel active pharmaceutical ingredient (API) or Monepantel finished formulations upon request. The Monepantel suppliers may include Monepantel API manufacturers, exporters, distributors and traders.

Monepantel GMP

Monepantel Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Monepantel GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Monepantel GMP manufacturer or Monepantel GMP API supplier for your needs.

Monepantel CoA

A Monepantel CoA (Certificate of Analysis) is a formal document that attests to Monepantel's compliance with Monepantel specifications and serves as a tool for batch-level quality control.

Monepantel CoA mostly includes findings from lab analyses of a specific batch. For each Monepantel CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Monepantel may be tested according to a variety of international standards, such as European Pharmacopoeia (Monepantel EP), Monepantel JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Monepantel USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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