Company profile for Gossamer Bio

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About

Gossamer Bio is a San Diego-based company focused on the discovery and development of novel and differentiated therapeutic products, to address high unmet needs amongst various targeted patient populations. Founded by the former Receptos executive team, Gossamer Bio’s strategy will be to leverage an asset-rich in-licensing environment, with a focus on areas of high unmet need, utilizing a team with a strong track record of e...
Gossamer Bio is a San Diego-based company focused on the discovery and development of novel and differentiated therapeutic products, to address high unmet needs amongst various targeted patient populations. Founded by the former Receptos executive team, Gossamer Bio’s strategy will be to leverage an asset-rich in-licensing environment, with a focus on areas of high unmet need, utilizing a team with a strong track record of execution in immunology, inflammation, fibrosis and oncology.

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CONTACT DETAILS

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Country
Country
U.S.A
Address
Address
3013 Science Park Road, Suite 200 San Diego, CA 92121
Telephone
Telephone
858-684-1300
youtube
YouTube
Twitter
Twitter

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NEWS #PharmaBuzz

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https://www.biospace.com/biospace-layoff-tracker

BIOSPACE
21 Mar 2026

https://www.biospace.com/business/gossamer-nearly-halves-workforce-in-savings-push-after-late-stage-hypertension-fail

BIOSPACE
19 Mar 2026

https://www.businesswire.com/news/home/20260317488156/en/Gossamer-Bio-Announces-Fourth-Quarter-and-Full-Year-2025-Financial-Results-and-Provides-Corporate-Update

BUSSINESSWIRE
17 Mar 2026

https://www.fiercebiotech.com/biotech/gossamer-bio-fails-phase-3-pulmonary-arterial-hypertension-trial-tries-thread-path-market

FIERCE BIOTECH
23 Feb 2026

https://www.businesswire.com/news/home/20260108468807/en/Gossamer-Bio-Announces-Inducement-Grant-Under-Nasdaq-Listing-Rule-5635c4

BUSINESSWIRE
08 Jan 2026

https://www.businesswire.com/news/home/20251209606832/en/Gossamer-Bio-Announces-Inducement-Grant-Under-Nasdaq-Listing-Rule-5635c4

BUSINESSWIRE
09 Dec 2025

Drugs in Development

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Details:

Respira is developing RT234 (vardenafil inhalation powder) as the first as-needed (PRN) therapy for use in pulmonary hypertension (PH).


Lead Product(s): Vardenafil Hydrochloride

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: RT234

Study Phase: Phase IIProduct Type: Miscellaneous

Recipient: Respira Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement September 25, 2025

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Gossamer Bio

U.S.A
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Health 2.0 Conference
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Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Details : Respira is developing RT234 (vardenafil inhalation powder) as the first as-needed (PRN) therapy for use in pulmonary hypertension (PH).

Product Name : RT234

Product Type : Miscellaneous

Upfront Cash : Undisclosed

September 25, 2025

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Details:

Gossamer Bio continues developing GB002 (seralutinib), an inhaled inhibitor for pulmonary hypertension, while Chiesi will commercialize it outside the U.S.


Lead Product(s): Seralutinib

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: Chiesi Group

Deal Size: $326.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration May 06, 2024

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Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Details : Gossamer Bio continues developing GB002 (seralutinib), an inhaled inhibitor for pulmonary hypertension, while Chiesi will commercialize it outside the U.S.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Undisclosed

May 06, 2024

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Details:

Gossamer intends to use the net proceeds to fund the ongoing development and commercialization of GB002 (seralutinib), a tyrosine kinase inhibitor targeting PDGFRα/β, CSF1R, and c-KIT, for the treatment of pulmonary arterial hypertension (PAH).


Lead Product(s): Seralutinib

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: New Enterprise Associates

Deal Size: $212.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement July 20, 2023

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Gossamer Bio

U.S.A
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Health 2.0 Conference
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Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Details : Gossamer intends to use the net proceeds to fund the ongoing development and commercialization of GB002 (seralutinib), a tyrosine kinase inhibitor targeting PDGFRα/β, CSF1R, and c-KIT, for the treatment of pulmonary arterial hypertension (PAH).

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Undisclosed

July 20, 2023

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Details:

The FDA has now placed a clinical hold on all trials of GB5121, which was being tested for primary central nervous system lymphoma. Now, all work related to GB5121 has been discontinued and the ongoing studies shelved.


Lead Product(s): GB5121

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase I/ Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 03, 2023

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Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Details : The FDA has now placed a clinical hold on all trials of GB5121, which was being tested for primary central nervous system lymphoma. Now, all work related to GB5121 has been discontinued and the ongoing studies shelved.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

April 03, 2023

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Details:

The efficacy results generated with GB002 (seralutinib) in the context of a favorable safety and tolerability profile highlight compelling potential differentiation for seralutinib as an anti-proliferative, anti-inflammatory, and anti-fibrotic therapeutic candidate.


Lead Product(s): Seralutinib

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 06, 2022

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Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Details : The efficacy results generated with GB002 (seralutinib) in the context of a favorable safety and tolerability profile highlight compelling potential differentiation for seralutinib as an anti-proliferative, anti-inflammatory, and anti-fibrotic therapeuti...

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

December 06, 2022

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Details:

Gossamer intends to use the net proceeds from the proposed financing to fund research and development of its other product candidates and development programs and for working capital and general corporate purposes.


Lead Product(s): Seralutinib

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: EcoR1 Capital

Deal Size: $120.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement July 13, 2022

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Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Details : Gossamer intends to use the net proceeds from the proposed financing to fund research and development of its other product candidates and development programs and for working capital and general corporate purposes.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Undisclosed

July 13, 2022

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Details:

Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. The primary objective for this trial is to determine the effect of GB002 on improving pulmonary hemodynamics in subjects with WHO Group 1 PAH who are Functional Class II and III.


Lead Product(s): Seralutinib

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable June 09, 2022

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Gossamer Bio

U.S.A
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Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Details : Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. The primary objective for this trial is to determine the effect of GB002 on improving pulmonary hemodynamics in subjects with WHO Group 1 PAH who are Functional Class II and III.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

June 09, 2022

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Details:

Neither statistically significant nor clinically meaningful differences were observed for primary endpoint and secondary endpoints, including histologic and mucosal healing endpoints, for either GB004 treatment group relative to placebo at week 12.


Lead Product(s): GB004

Therapeutic Area: Immunology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 25, 2022

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Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Details : Neither statistically significant nor clinically meaningful differences were observed for primary endpoint and secondary endpoints, including histologic and mucosal healing endpoints, for either GB004 treatment group relative to placebo at week 12.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

April 25, 2022

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Details:

GB5121 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Central Nervous System Lymphoma.


Lead Product(s): GB5121

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 16, 2022

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Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Details : GB5121 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Central Nervous System Lymphoma.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

February 16, 2022

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Details:

Seralutinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Pulmonary Arterial Hypertension.


Lead Product(s): Seralutinib

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable March 25, 2021

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10

Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Gossamer Bio

U.S.A
arrow
Health 2.0 Conference
Not Confirmed

Details : Seralutinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Pulmonary Arterial Hypertension.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

March 25, 2021

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