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    Aspen says new Latam and Eli Lilly portfolio boosting earnings

    05 Mar 2025

    // REUTERS

    Aspen shells out $100M for Sandoz's China unit, pipeline

    04 Dec 2023

    // Zoey Becker FIERCE PHARMA

    Novo Nordisk taps Aspen to help produce insulin for Africa

    19 Sep 2023

    // Fraiser Kansteiner FIERCE PHARMA

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    South African-based Aspen is a supplier of branded and generic pharmaceuticals in more than 150 countries across the world and of consumer and nutritional products in selected territories. Aspen is represented in South Africa, Australia, Hong Kong, Malaysia, Philippines, Taiwan, Japan, Kenya, Nigeria, Tanzania, Uganda, Ireland, United Arab Emirates, France, Germany, the Netherlands, Mauritius, Brazil, Mexico, Venezuela and the United States of America. Acquisitions announced in 2013 will further extend the Group’s emerging market presence to the Commonwealth of Independent States, comprising Russia and the former Soviet Republics.

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    Aspen House, Aspen Park 98 Armstrong Avenue La Lucia Ridge, Durban
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    jkemmeren@nl.aspenpharma.com
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    US drug shortages reduce 16% YoY in Q1 2025; CNS drugs, antimicrobials face highest scarcities

    US drug shortages reduce 16% YoY in Q1 2025; CNS drugs, antimicrobials face highest scarcities

    The pharmaceutical industry in the United States continued to grapple with drug shortages during the first quarter (Q1) of 2025. According to the American Society of Health‑System Pharmacists (ASHP), the total number of active shortages stood at 270 as of March 31, 2025 — only slightly below the 277 reported in September 2024, but down 16.4 percent from an all‑time high of 323 reported in Q1 2024.These numbers imply that while dramatic surges in drug shortages may have subsided, underlying vulnerabilities in manufacturing, supply chains, and raw‑material sourcing continue to frustrate efforts towards a durable resolution.A deeper analysis of these drug scarcities reveals that 41 percent of the 270 active shortages first emerged in 2022 or earlier. This implies that many of the current disruptions have become chronic in nature and are exerting pressure on pharmacy operations. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available)CNS drugs dominate with 49 meds in short supply; antimicrobials face shortage of 39 drugsClass‑specific analysis reveals that central nervous system (CNS) agents remained the most disrupted category, with 49 distinct CNS drugs having faced scarcities during Q1. This group spans anxiolytics (anti-anxiety drugs) such as clonazepam and flurazepam, sedatives like lorazepam and midazolam, and stimulants such as methylphenidate and lisdexamfetamine. These shortages pose two challenges — controlling seizures and managing sedation in acute care settings. After CNS agents, antimicrobials was the second‑largest category, with shortages affecting 39 drugs. Key antibacterial and anti-fungal agents such as cefotaxime sodium powder for injection, clindamycin phosphate, rifampin, and metronidazole find themselves on ASHP’s active‑shortage roster, threatening both routine hospital protocols and emergency sepsis management.Fluids and electrolytes occupied the third spot, with 29 items facing shortage in Q1 2025. Hormone agents, including insulin analogs, ranked fourth with 24 drugs in short supply.Chemotherapy medications rounded out the top five categories, with 23 antineoplastic agents (a broad class of medications used to treat cancer) flagged as actively constrained in Q1 2025. Notable shortages included azacitidine, carboplatin, methotrexate, and streptozocin. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available) US faces 26 new shortages; Pharmacopeia list warns of 100 vulnerable medicationsThe first quarter saw the emergence of 26 new shortage declarations, emphasizing that even drugs previously deemed reliably sourced can fall into scarcity. The US has been facing a shortage of attention deficit hyperactivity disorder (ADHD) drugs since 2022. The new shortages included ADHD transdermal patch methylphenidate, peginterferon alfa‑2a (Pegasys) used in chronic hepatitis B and C, and bacitracin ophthalmic ointment.The fragility of the pharmaceutical supply chains has been particularly evident in the aftermath of natural disasters. Hurricane Helene’s flooding at Baxter’s Marion, North Carolina, facility deeply affected IV‑solution supply lines. Baxter supplies roughly 60 percent of the US’ IV fluids and the ASHP report listed “hurricane” as the reason behind nine percent of drug shortages, as of January 2025.Regulatory and policy interventions continue to evolve. The US Pharmacopeia’s inaugural Vulnerable Medicines List, launched in 2025, identifies 100 drugs at the highest risk of future shortages, with a particular focus on injectables (comprising 71 percent of the list) and essential hospital care.Antibiotics, medications for pain management and oncology are the other drugs on the list. Although 61 percent of these vulnerable medicines were not in active shortage at the time of listing, their inclusion is intended to galvanize manufacturers and purchasing organizations to bolster inventories.Meanwhile, the Government Accountability Office in the US has called on the Department of Health and Human Services (HHS) to establish a formal coordination mechanism, warning that elimination of the HHS supply‑chain coordinator role in May 2025 risks fragmenting federal response efforts. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available) Global shortages mirror US patterns; Europe launches monitoring platform Globally, we notice comparable trends. For instance, Europe has rolled out the European Shortages Monitoring Platform (ESMP) this year in order to centralize shortage reporting across member states. Critical‑medicine shortages in the EU — in areas such as oncology, ADHD, and critical care analgesics — mirror US patterns. The European Medicines Agency’s shortage list currently holds 37 human drugs.According to Health Canada’s May 12, 2025 update, its Tier 3 list had 18 drug shortages that are considered to have the greatest impact on Canada’s drug supply and health‑care system. Tier 3 designation is based on medical necessity and minimal availability of alternatives.In hematology and oncology, scarcity of essential drugs like Oncaspar for acute lymphoblastic leukemia, idarubicin and lomustine for leukemias and brain tumors, anagrelide for thrombocythemia, and preservative‑free methotrexate for various malignancies underscore the impact these drug shortages can have on treatment. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available) Our viewThe global pharma supply chain is dealing with a fresh wave of uncertainties, especially with the likelihood of tariffs on drugs imported into the US. Analysts warn that the proposed pharmaceutical tariffs could exacerbate supply issues.Over 50 percent of drugs used in the US are manufactured abroad. Generic sterile injectable drugs — like chemotherapy medications and IV saline — are particularly vulnerable due to their complex manufacturing processes and low profit margins. Generic drugs (which account for 90 percent of prescriptions filled in the US) could face increased pressure, as many rely on raw materials from China and India. This could result in more severe drug shortages in the future. 
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    NEWS #PharmaBuzz

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    Aspen says new Latam and Eli Lilly portfolio boosting earnings
    Aspen says new Latam and Eli Lilly portfolio boosting earnings

    05 Mar 2025

    // REUTERS

    https://www.reuters.com/business/healthcare-pharmaceuticals/african-drugmaker-aspen-posts-5-rise-half-year-earnings-2025-03-03/

    REUTERS
    05 Mar 2025
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    Aspen shells out $100M for Sandoz's China unit, pipeline
    Aspen shells out $100M for Sandoz's China unit, pipeline

    04 Dec 2023

    // Zoey Becker FIERCE PHARMA

    https://www.fiercepharma.com/pharma/south-africas-aspen-expands-reach-china-100m-buy-sandoz-chinese-business

    Zoey Becker FIERCE PHARMA
    04 Dec 2023
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    Novo Nordisk taps Aspen to help produce insulin for Africa
    Novo Nordisk taps Aspen to help produce insulin for Africa

    19 Sep 2023

    // Fraiser Kansteiner FIERCE PHARMA

    https://www.fiercepharma.com/pharma/following-eli-lilly-novo-nordisk-links-aspen-produce-insulin-africa

    Fraiser Kansteiner FIERCE PHARMA
    19 Sep 2023
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    Aspen and Lilly enter into agreement in South Africa and the rest of Sub-Saharan Africa
    Aspen and Lilly enter into agreement in South Africa and the rest of Sub-Saharan Africa

    30 Aug 2023

    // PRESS RELEASE

    https://www.aspenpharma.com/aspen-and-lilly-enter-into-agreement-in-south-africa-and-the-rest-of-sub-saharan-africa/

    PRESS RELEASE
    30 Aug 2023
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    Aspen revenue exceeds R40 billion with accelerated medium-term growth anticipated
    Aspen revenue exceeds R40 billion with accelerated medium-term growth anticipated

    30 Aug 2023

    // PRESS RELEASE

    https://www.aspenpharma.com/aspen-revenue-exceeds-r40-billion-with-accelerated-medium-term-growth-anticipated/

    PRESS RELEASE
    30 Aug 2023
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    Aspen hosts Mandela Day for 13th consecutive year, having reached 865 000 beneficiaries
    Aspen hosts Mandela Day for 13th consecutive year, having reached 865 000 beneficiaries

    18 Jul 2023

    // PRESS RELEASE

    https://www.aspenpharma.com/aspen-hosts-mandela-day-for-13th-consecutive-year-having-reached-865-000-beneficiaries/

    PRESS RELEASE
    18 Jul 2023
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    Drugs in Development

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    Aspen Announces Local Availability of Lilly’s Mounjaro

    Details:

    Mounjaro (tirzepatide) injection is an obesity treatment targeting GIP and GLP-1 hormone receptors. Currently it is indicated for the treatment of type 2 diabetes mellitus and obesity.


    Lead Product(s): Tirzepatide

    Therapeutic Area: Endocrinology Brand Name: Mounjaro

    Study Phase: Approved FDFProduct Type: Peptide

    Sponsor: Eli Lilly

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable December 20, 2024

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    Lead Product(s) : Tirzepatide

    Therapeutic Area : Endocrinology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Eli Lilly

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Aspen Announces Local Availability of Lilly’s Mounjaro

    Details : Mounjaro (tirzepatide) injection is an obesity treatment targeting GIP and GLP-1 hormone receptors. Currently it is indicated for the treatment of type 2 diabetes mellitus and obesity.

    Product Name : Mounjaro

    Product Type : Peptide

    Upfront Cash : Inapplicable

    December 20, 2024

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    Aspen, CEPI And The Bill & Melinda Gates Foundation Expand Commitments To Improve Access To Vaccines In Africa

    Details:

    PNEUMOSIL® (pneumococcal polysaccharide conjugate vaccine – adsorbed, 10 Valent), a well-designed vaccine, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countries.


    Lead Product(s): Pneumococcal Polysaccharide Conjugate Vaccine

    Therapeutic Area: Infections and Infectious Diseases Brand Name: Pneumosil

    Study Phase: Approved FDFProduct Type: Vaccine

    Sponsor: Gates Foundation

    Deal Size: $30.0 million Upfront Cash: Undisclosed

    Deal Type: Funding December 12, 2022

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    Lead Product(s) : Pneumococcal Polysaccharide Conjugate Vaccine

    Therapeutic Area : Infections and Infectious Diseases

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Gates Foundation

    Deal Size : $30.0 million

    Deal Type : Funding

    DEALS_DEV arrow-down

    Aspen, CEPI And The Bill & Melinda Gates Foundation Expand Commitments To Improve Access To Vaccin...

    Details : PNEUMOSIL® (pneumococcal polysaccharide conjugate vaccine – adsorbed, 10 Valent), a well-designed vaccine, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countries.

    Product Name : Pneumosil

    Product Type : Vaccine

    Upfront Cash : Undisclosed

    December 12, 2022

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    Aspen Concludes a Collaboration Agreement to Manufacture and Make Available Four Aspen-Branded Vaccines for Africa

    Details:

    PNEUMOSIL® (Pneumococcal Conjugate Vaccine – adsorbed, 10 Valent), a well-designed vaccine with relevant serotypes, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countries.


    Lead Product(s): 10-Valent Pneumococcal Polysaccharide Conjugate Vaccine

    Therapeutic Area: Infections and Infectious Diseases Brand Name: Undisclosed

    Study Phase: Approved FDFProduct Type: Vaccine

    Sponsor: Serum Institute of India

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Collaboration August 31, 2022

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    Lead Product(s) : 10-Valent Pneumococcal Polysaccharide Conjugate Vaccine

    Therapeutic Area : Infections and Infectious Diseases

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Serum Institute of India

    Deal Size : Undisclosed

    Deal Type : Collaboration

    DEALS_DEV arrow-down

    Aspen Concludes a Collaboration Agreement to Manufacture and Make Available Four Aspen-Branded Vac...

    Details : PNEUMOSIL® (Pneumococcal Conjugate Vaccine – adsorbed, 10 Valent), a well-designed vaccine with relevant serotypes, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countrie...

    Product Name : Undisclosed

    Product Type : Vaccine

    Upfront Cash : Undisclosed

    August 31, 2022

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    Australia Registers First Eye Drops to Slow Short-sightedness Progress in Children

    Details:

    EIKANCE (atropine sulfate monohydrate eye drops) are available on prescription for children aged 4 to 14 years, as a treatment to slow the progression of myopia and may be initiated in children when myopia progresses by 1 or more diopters per year.


    Lead Product(s): Atropine Sulfate

    Therapeutic Area: Ophthalmology Brand Name: Eikance

    Study Phase: Approved FDFProduct Type: Other Small Molecule

    Sponsor: Inapplicable

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable March 18, 2022

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    Lead Product(s) : Atropine Sulfate

    Therapeutic Area : Ophthalmology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Australia Registers First Eye Drops to Slow Short-sightedness Progress in Children

    Details : EIKANCE (atropine sulfate monohydrate eye drops) are available on prescription for children aged 4 to 14 years, as a treatment to slow the progression of myopia and may be initiated in children when myopia progresses by 1 or more diopters per year.

    Product Name : Eikance

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    March 18, 2022

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    Debiopharm And Aspen Partner To Launch Prostate Cancer Drug Trelstar® In South Africa

    Details:

    Debiopharm to enter into this new alliance with Aspen, a well-established and trusted pharmaceutical partner for the commercialization of Trelstar® in South Africa and recognize the therapeutic benefits that Trelstar® could bring to prostate cancer patients in this region.


    Lead Product(s): Triptorelin Pamoate

    Therapeutic Area: Oncology Brand Name: Trelstar

    Study Phase: Approved FDFProduct Type: Hormone

    Sponsor: Debiopharm

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Partnership January 02, 2022

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    Lead Product(s) : Triptorelin Pamoate

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Debiopharm

    Deal Size : Undisclosed

    Deal Type : Partnership

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    Debiopharm And Aspen Partner To Launch Prostate Cancer Drug Trelstar® In South Africa

    Details : Debiopharm to enter into this new alliance with Aspen, a well-established and trusted pharmaceutical partner for the commercialization of Trelstar® in South Africa and recognize the therapeutic benefits that Trelstar® could bring to prostate cancer pat...

    Product Name : Trelstar

    Product Type : Hormone

    Upfront Cash : Undisclosed

    January 02, 2022

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    Johnson & Johnson Discussions to License its COVID-19 Vaccine to Aspen Reach Advanced Stage

    Details:

    The license under discussion would enable Aspen, using COVID-19 vaccine JNJ-78436735, drug substance supplied by Johnson & Johnson, to produce Aspen-branded finished vaccine for sale to public sector markets in Africa.


    Lead Product(s): Ad26.COV2.S

    Therapeutic Area: Infections and Infectious Diseases Brand Name: JNJ-78436735

    Study Phase: Approved FDFProduct Type: Vaccine

    Sponsor: Johnson & Johnson

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement November 30, 2021

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    Lead Product(s) : Ad26.COV2.S

    Therapeutic Area : Infections and Infectious Diseases

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Johnson & Johnson

    Deal Size : Undisclosed

    Deal Type : Licensing Agreement

    DEALS_DEV arrow-down

    Johnson & Johnson Discussions to License its COVID-19 Vaccine to Aspen Reach Advanced Stage

    Details : The license under discussion would enable Aspen, using COVID-19 vaccine JNJ-78436735, drug substance supplied by Johnson & Johnson, to produce Aspen-branded finished vaccine for sale to public sector markets in Africa.

    Product Name : JNJ-78436735

    Product Type : Vaccine

    Upfront Cash : Undisclosed

    November 30, 2021

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    Acino Acquires Selected Aspen Brands in South Africa

    Details:

    The transaction includes Trustan, Altosec, Zuvamor, Ciavor, Grantryl and Aspen Granisetron brands. To secure uninterrupted patient access to these medicines, the parties have also signed a manufacturing and supply agreement.


    Lead Product(s): Esomeprazole Magnesium

    Therapeutic Area: Gastroenterology Brand Name: Trustan

    Study Phase: Approved FDFProduct Type: Other Small Molecule

    Sponsor: Acino Pharma

    Deal Size: $119.4 million Upfront Cash: Undisclosed

    Deal Type: Acquisition October 22, 2021

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    Lead Product(s) : Esomeprazole Magnesium

    Therapeutic Area : Gastroenterology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Acino Pharma

    Deal Size : $119.4 million

    Deal Type : Acquisition

    DEALS_DEV arrow-down

    Acino Acquires Selected Aspen Brands in South Africa

    Details : The transaction includes Trustan, Altosec, Zuvamor, Ciavor, Grantryl and Aspen Granisetron brands. To secure uninterrupted patient access to these medicines, the parties have also signed a manufacturing and supply agreement.

    Product Name : Trustan

    Product Type : Other Small Molecule

    Upfront Cash : Undisclosed

    October 22, 2021

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    Aspen Concludes Strategic Partnership with U.S-Based Avion Pharmaceuticals

    Details:

    Avion Pharmaceuticals gets exclusive rights to relaunch Cenestin® in the USA. Cenestin® is the only plant-derived mixture of nine conjugated estrogens indicated for treatment of moderate to severe symptoms of vasomotor, and vulvar and vaginal atrophy due to menopause.


    Lead Product(s): Conjugated Estrogens

    Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: Cenestin

    Study Phase: Approved FDFProduct Type: Other Small Molecule

    Sponsor: Avion Pharmaceuticals

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Partnership December 11, 2020

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    Lead Product(s) : Conjugated Estrogens

    Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Avion Pharmaceuticals

    Deal Size : Undisclosed

    Deal Type : Partnership

    DEALS_DEV arrow-down

    Aspen Concludes Strategic Partnership with U.S-Based Avion Pharmaceuticals

    Details : Avion Pharmaceuticals gets exclusive rights to relaunch Cenestin® in the USA. Cenestin® is the only plant-derived mixture of nine conjugated estrogens indicated for treatment of moderate to severe symptoms of vasomotor, and vulvar and vaginal atrophy d...

    Product Name : Cenestin

    Product Type : Other Small Molecule

    Upfront Cash : Undisclosed

    December 11, 2020

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    Aspen Concludes Agreement to Manufacture and Make Available Aspenovax Throughout Africa

    Details:

    The agreement aims to manufacture and make available Aspenovax, an Aspen-branded COVID-19 vaccine, across Africa.


    Lead Product(s): COVID-19 Vaccine

    Therapeutic Area: Infections and Infectious Diseases Brand Name: Aspenovax

    Study Phase: Approved FDFProduct Type: Vaccine

    Sponsor: Johnson & Johnson Innovative Medicine

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Agreement September 08, 2020

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    Lead Product(s) : COVID-19 Vaccine

    Therapeutic Area : Infections and Infectious Diseases

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Johnson & Johnson Innovative Medicine

    Deal Size : Undisclosed

    Deal Type : Agreement

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    Aspen Concludes Agreement to Manufacture and Make Available Aspenovax Throughout Africa

    Details : The agreement aims to manufacture and make available Aspenovax, an Aspen-branded COVID-19 vaccine, across Africa.

    Product Name : Aspenovax

    Product Type : Vaccine

    Upfront Cash : Undisclosed

    September 08, 2020

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    Divestment of Aspen’s European Thrombosis Business to Mylan and Withdrawal of Cautionary

    Details:

    Under the terms of the agreement, Mylan Ireland Limited will acquire the commercialisation rights and related intellectual property relating to Aspen’s Thrombosis Business in Europe which includes Arixtra, Fraxiparine, Mono-Embolex and Orgaran.


    Lead Product(s): Fondaparinux Sodium

    Therapeutic Area: Hematology Brand Name: Arixtra

    Study Phase: Approved FDFProduct Type: Other Small Molecule

    Sponsor: Viatris

    Deal Size: $757.2 million Upfront Cash: $310.4 million

    Deal Type: Acquisition August 09, 2020

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    10

    Aspen Pharmacare Holdings

    South Africa
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    APS Symposium
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    Lead Product(s) : Fondaparinux Sodium

    Therapeutic Area : Hematology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Viatris

    Deal Size : $757.2 million

    Deal Type : Acquisition

    DEALS_DEV arrow-down

    Divestment of Aspen’s European Thrombosis Business to Mylan and Withdrawal of Cautionary

    Details : Under the terms of the agreement, Mylan Ireland Limited will acquire the commercialisation rights and related intellectual property relating to Aspen’s Thrombosis Business in Europe which includes Arixtra, Fraxiparine, Mono-Embolex and Orgaran.

    Product Name : Arixtra

    Product Type : Other Small Molecule

    Upfront Cash : $310.4 million

    August 09, 2020

    Aspen API Comapny Banner

    Stock Recap
    #PipelineProspector

    Data Compilation
    #PharmaFlow

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