Find Ziresovir manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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NDC API

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REF. STANDARDS OR IMPURITIES

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Chemistry

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Also known as: 1422500-60-4, Ak0529, Ziresovir [inn], Ro-0529, Ak-0529, Xcf42d7ag4
Molecular Formula
C22H25N5O3S
Molecular Weight
439.5  g/mol
InChI Key
GAAICKUTDBZCMT-UHFFFAOYSA-N
FDA UNII
XCF42D7AG4

Ziresovir
Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)).
1 2D Structure

Ziresovir

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[(3-aminooxetan-3-yl)methyl]-2-(1,1-dioxo-3,5-dihydro-2H-16,4-benzothiazepin-4-yl)-6-methylquinazolin-4-amine
2.1.2 InChI
InChI=1S/C22H25N5O3S/c1-15-6-7-18-17(10-15)20(24-12-22(23)13-30-14-22)26-21(25-18)27-8-9-31(28,29)19-5-3-2-4-16(19)11-27/h2-7,10H,8-9,11-14,23H2,1H3,(H,24,25,26)
2.1.3 InChI Key
GAAICKUTDBZCMT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC2=C(C=C1)N=C(N=C2NCC3(COC3)N)N4CCS(=O)(=O)C5=CC=CC=C5C4
2.2 Other Identifiers
2.2.1 UNII
XCF42D7AG4
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ak-0529

2. Ak0529

3. N-((3-aminooxetan-3-yl)methyl)-2-(1,1-dioxo-3,5-dihydro-2h-1lambda6,4-benzothiazepin-4-yl)-6-methylquinazolin-4-amine

4. Ro-0529

5. Ro0529

2.3.2 Depositor-Supplied Synonyms

1. 1422500-60-4

2. Ak0529

3. Ziresovir [inn]

4. Ro-0529

5. Ak-0529

6. Xcf42d7ag4

7. Chembl4468815

8. 4-(4-(((3-aminooxetan-3-yl)methyl)amino)-6-methylquinazolin-2-yl)-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine 1,1-dioxide

9. 4-quinazolinamine, N-((3-amino-3-oxetanyl)methyl)-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5h)-yl)-6-methyl-

10. N-((3-amino-3-oxetanyl)methyl)-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5h)-yl)-6-methyl-4-quinazolinamine

11. N-((3-aminooxetan-3-yl)methyl)-2-(1,1-dioxido-2,3-dihydro-1,4-benzothiazepin-4(5h)-yl)-6-methylquinazolin-4-amine

12. N-[(3-aminooxetan-3-yl)methyl]-2-(1,1-dioxo-3,5-dihydro-2h-1lambda6,4-benzothiazepin-4-yl)-6-methylquinazolin-4-amine

13. N-((3-aminooxetan-3-yl)methyl)-2-(1,1-dioxo-3,5-dihydro-2h-1lambda6,4-benzothiazepin-4-yl)-6-methylquinazolin-4-amine

14. N-[(3-aminooxetan-3-yl)methyl]-2-(1,1-dioxido-2,3-dihydro-1,4-benzothiazepin-4(5h)-yl)-6-methylquinazolin-4-amine

15. Unii-xcf42d7ag4

16. Ziresovir [who-dd]

17. Schembl14704847

18. Dtxsid901028129

19. Bdbm50516304

20. Db15145

21. Az171068

22. Hy-109142

23. Cs-0086934

24. A937667

25. 4-(4-(((3-aminooxetan-3-yl)methyl)amino)-6-methylquinazolin-2-yl)-2,3,4,5-tetrahydro-1h-1.lambda.6,4-benzothiazepine-1,1-dione

26. 4-(4-(((3-aminooxetan-3-yl)methyl)amino)-6-methylquinazolin-2-yl)-2,3,4,5-tetrahydro-1h-1lambda6,4-benzothiazepine-1,1-dione

27. 4-(4-(((3-aminooxetan-3-yl)methyl)amino)-6-methylquinazolin-2-yl)-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine1,1-dioxide

2.4 Create Date
2013-03-21
3 Chemical and Physical Properties
Molecular Weight 439.5 g/mol
Molecular Formula C22H25N5O3S
XLogP31.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass439.16781085 g/mol
Monoisotopic Mass439.16781085 g/mol
Topological Polar Surface Area119 Ų
Heavy Atom Count31
Formal Charge0
Complexity740
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


ABOUT THIS PAGE

Looking for 1422500-60-4 / Ziresovir API manufacturers, exporters & distributors?

Ziresovir manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ziresovir API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ziresovir manufacturer or Ziresovir supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ziresovir manufacturer or Ziresovir supplier.

PharmaCompass also assists you with knowing the Ziresovir API Price utilized in the formulation of products. Ziresovir API Price is not always fixed or binding as the Ziresovir Price is obtained through a variety of data sources. The Ziresovir Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ziresovir

Synonyms

1422500-60-4, Ak0529, Ziresovir [inn], Ro-0529, Ak-0529, Xcf42d7ag4

Cas Number

1422500-60-4

Unique Ingredient Identifier (UNII)

XCF42D7AG4

About Ziresovir

Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)).

Ziresovir Manufacturers

A Ziresovir manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ziresovir, including repackagers and relabelers. The FDA regulates Ziresovir manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ziresovir API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ziresovir Suppliers

A Ziresovir supplier is an individual or a company that provides Ziresovir active pharmaceutical ingredient (API) or Ziresovir finished formulations upon request. The Ziresovir suppliers may include Ziresovir API manufacturers, exporters, distributors and traders.

Ziresovir GMP

Ziresovir Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ziresovir GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ziresovir GMP manufacturer or Ziresovir GMP API supplier for your needs.

Ziresovir CoA

A Ziresovir CoA (Certificate of Analysis) is a formal document that attests to Ziresovir's compliance with Ziresovir specifications and serves as a tool for batch-level quality control.

Ziresovir CoA mostly includes findings from lab analyses of a specific batch. For each Ziresovir CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ziresovir may be tested according to a variety of international standards, such as European Pharmacopoeia (Ziresovir EP), Ziresovir JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ziresovir USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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