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Looking for 1648843-04-2 / SX-682 API manufacturers, exporters & distributors?

SX-682 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of SX-682 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right SX-682 manufacturer or SX-682 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred SX-682 manufacturer or SX-682 supplier.

PharmaCompass also assists you with knowing the SX-682 API Price utilized in the formulation of products. SX-682 API Price is not always fixed or binding as the SX-682 Price is obtained through a variety of data sources. The SX-682 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

SX-682

Synonyms

1648843-04-2, Unii-h5212r2dpm, H5212r2dpm, (2-(((5-((4-fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid, [2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid, (2-(((5-((4-fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronicacid

Cas Number

1648843-04-2

Unique Ingredient Identifier (UNII)

H5212R2DPM

About SX-682

CXCR1/2 Inhibitor SX-682 is an orally bioavailable, selective and reversible antagonist of C-X-C motif chemokine receptors 1 (CXCR1) and 2 (CXCR2), with potential anti-inflammatory and antineoplastic activities. Upon administration CXCR1/2 inhibitor SX-682 selectively and allosterically binds to CXCR 1 and 2 and inhibits their activation by tumor-secreted chemokines. This inhibits CXCR1/2-mediated signaling, reduces both recruitment and migration of immunosuppressive myeloid-derived suppressor cells (MDSCs) and neutrophils in the tumor microenvironment (TME), inhibits inflammatory processes and abrogates the immunosuppressive-induced nature of the TME. This allows effector cells, such as natural killer (NK) cells and cytotoxic T-lymphocytes (CTLs), to kill and eliminate cancer cells. This inhibits tumor cell migration, metastasis, angiogenesis and tumor cell proliferation. CXCR1 and 2, G protein-coupled receptor proteins located on myeloid cells and certain tumor cells, play key roles in the immunosuppressive nature of the TME, tumor metastasis, therapy-resistance and myeloid cell suppression. They play a key role in inflammation and their expression is elevated in several inflammatory-driven diseases.

SX-682 Manufacturers

A SX-682 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of SX-682, including repackagers and relabelers. The FDA regulates SX-682 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. SX-682 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

SX-682 Suppliers

A SX-682 supplier is an individual or a company that provides SX-682 active pharmaceutical ingredient (API) or SX-682 finished formulations upon request. The SX-682 suppliers may include SX-682 API manufacturers, exporters, distributors and traders.

SX-682 GMP

SX-682 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of SX-682 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right SX-682 GMP manufacturer or SX-682 GMP API supplier for your needs.

SX-682 CoA

A SX-682 CoA (Certificate of Analysis) is a formal document that attests to SX-682's compliance with SX-682 specifications and serves as a tool for batch-level quality control.

SX-682 CoA mostly includes findings from lab analyses of a specific batch. For each SX-682 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

SX-682 may be tested according to a variety of international standards, such as European Pharmacopoeia (SX-682 EP), SX-682 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (SX-682 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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