Sapropterin Dihydrochloride

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

12 API Suppliers, 8 USDMF, 1 EU WC, 8 NDC API, 7 Listed Suppliers

DEVELOPMENTS

2 Drug(s) in Development

2 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Imports

DOSSIERs // Finished Dosage Formulations

33 Dossiers, 12 FDA Orange Book, 4 Europe, 5 Canada, 11 Australia, 1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

Suppliers, 13 SPI Pharma, 6 BASF, 5 Gangwal Chemicals, 4 Gangwal Healthcare, 4 Boai NKY Pharmaceuticals Ltd, 3 Roquette, 3 Microlex e.U, 2 Kerry, 2 Rochem International Inc, 2 Alcedo Pharmachem, 2 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 2 Pharmatrans-Sanaq, 1 Bioplus Life Sciences, 1 Pharm-RX Chemical, 1 Ingredion Pharma Solutions, 1 Prachin Chemical, 1 DKSH, 1 Pfanstiehl, 1 NEWEDGE Overseas, 1 Minakem, 1 Sigachi Industries, 1 Chynops Pharma, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Ulanqab Kema New Material, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Jai Radhe Sales

EXCIPIENTS BY APPLICATIONS

23 Fillers, Diluents & Binders, 17 Direct Compression, 16 Disintegrants & Superdisintegrants, 14 Chewable & Orodispersible Aids, 11 Taste Masking, 7 Granulation, 6 Lubricants & Glidants, 5 Thickeners and Stabilizers, 4 Co-Processed Excipients, 3 Parenteral, 3 Solubilizers, 2 Coating Systems & Additives, 1 API Stability Enhancers, 1 Film Formers & Plasticizers

GLOBAL SALES INFORMATION

10 US Medicaid Prescriptions, 3 Finished Drug Prices

MARKET PLACE

14 APIs, 1 DOSSIERS // FDF

PATENTS

42 US Patents, 4 Health Canada Patents

DIGITAL CONTENT

1 Data Compilations & Company Tracker #PharmaFlow, 30 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

17,642

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

204.00

Annual Reports

434.00

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as:

Molecular Formula

C₉H₁₇Cl₂N₅O₃

Molecular Weight

314.17 g/mol

InChI Key

RKSUYBCOVNCALL-NTVURLEBSA-N

1 2D Structure

Sapropterin Dihydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-1H-pteridin-4-one;dihydrochloride

2.1.2 InChI

InChI=1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1

2.1.3 InChI Key

RKSUYBCOVNCALL-NTVURLEBSA-N

2.1.4 Canonical SMILES

CC(C(C1CNC2=C(N1)C(=O)N=C(N2)N)O)O.Cl.Cl

2.1.5 Isomeric SMILES

C[C@@H]([C@@H]([C@H]1CNC2=C(N1)C(=O)N=C(N2)N)O)O.Cl.Cl

2.2 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₉H₁₇Cl₂N₅O₃
Molecular Weight	314.17 g/mol
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	313.0708448 g/mol
Monoisotopic Mass	313.0708448 g/mol
Topological Polar Surface Area	132 A^2
Heavy Atom Count	19
Formal Charge	0
Complexity	405
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

Find Sapropterin Hydrochloride manufacturers, exporters & distributors on PharmaCompass

Sapropterin Dihydrochloride

Sapropterin Dihydrochloride

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

12 API Suppliers

8 USDMF

1 EU WC

8 NDC API

7 Listed Suppliers

DEVELOPMENTS

2 Drug(s) in Development

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Imports

DOSSIERs // Finished Dosage Formulations

33 Dossiers

12 FDA Orange Book

4 Europe

5 Canada

11 Australia

1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

Suppliers

13 SPI Pharma

6 BASF

5 Gangwal Chemicals

4 Gangwal Healthcare

4 Boai NKY Pharmaceuticals Ltd

3 Roquette

3 Microlex e.U

2 Kerry

2 Rochem International Inc

2 Alcedo Pharmachem

2 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

2 Pharmatrans-Sanaq

1 Bioplus Life Sciences

1 Pharm-RX Chemical

1 Ingredion Pharma Solutions

1 Prachin Chemical

1 DKSH

1 Pfanstiehl

1 NEWEDGE Overseas

1 Minakem

1 Sigachi Industries

1 Chynops Pharma

1 Shijiazhuang Huaxu Pharmaceutical

1 Ulanqab Kema New Material

1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Jai Radhe Sales

EXCIPIENTS BY APPLICATIONS

23 Fillers, Diluents & Binders

17 Direct Compression

16 Disintegrants & Superdisintegrants

14 Chewable & Orodispersible Aids

11 Taste Masking

7 Granulation

6 Lubricants & Glidants

5 Thickeners and Stabilizers

4 Co-Processed Excipients

3 Parenteral

3 Solubilizers

2 Coating Systems & Additives

1 API Stability Enhancers

1 Film Formers & Plasticizers

GLOBAL SALES INFORMATION

10 US Medicaid Prescriptions

3 Finished Drug Prices

MARKET PLACE

14 APIs

1 DOSSIERS // FDF

PATENTS

42 US Patents

4 Health Canada Patents

DIGITAL CONTENT

1 Data Compilations & Company Tracker #PharmaFlow

30 News