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    Chemistry

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    Also known as:
    Molecular Formula
    C9H17Cl2N5O3
    Molecular Weight
    314.17  g/mol
    InChI Key
    RKSUYBCOVNCALL-NTVURLEBSA-N
    Sapropterin Hydrochloride
    1 2D Structure

    Sapropterin Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-1H-pteridin-4-one;dihydrochloride
    2.1.2 InChI
    InChI=1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1
    2.1.3 InChI Key
    RKSUYBCOVNCALL-NTVURLEBSA-N
    2.1.4 Canonical SMILES
    CC(C(C1CNC2=C(N1)C(=O)N=C(N2)N)O)O.Cl.Cl
    2.1.5 Isomeric SMILES
    C[C@@H]([C@@H]([C@H]1CNC2=C(N1)C(=O)N=C(N2)N)O)O.Cl.Cl
    2.2 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 314.17 g/mol
    Molecular Formula C9H17Cl2N5O3
    Hydrogen Bond Donor Count8
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count2
    Exact Mass313.0708448 g/mol
    Monoisotopic Mass313.0708448 g/mol
    Topological Polar Surface Area132 A^2
    Heavy Atom Count19
    Formal Charge0
    Complexity405
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3

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C.BERNASCONI 5 6830 - CHIASSO SDNF SWITZERLAND","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1743791400,"product":"SAPROPTERINE API D01APIM2A4 BATCH NO.A250314007 TOLVAPTAN","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"DIPHARMA S A","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"PAR FORMULATIONS PRIVATE LTD","customerCountry":"INDIA","quantity":"18.30","actualQuantity":"18.3","unit":"KGS","unitRateFc":"37500","totalValueFC":"694252.5","currency":"USD","unitRateINR":"3247500","date":"05-Apr-2025","totalValueINR":"59429250","totalValueInUsd":"694252.5","indian_port":"Madras Air","hs_no":"29339990","bill_no":"9311654","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"PIAZZA COL. 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    04-Mar-2022
    23-Sep-2025
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    Looking for / Sapropterin Hydrochloride API manufacturers, exporters & distributors?

    Sapropterin Hydrochloride manufacturers, exporters & distributors 1

    48

    PharmaCompass offers a list of Sapropterin Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sapropterin Hydrochloride manufacturer or Sapropterin Hydrochloride supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sapropterin Hydrochloride manufacturer or Sapropterin Hydrochloride supplier.

    PharmaCompass also assists you with knowing the Sapropterin Hydrochloride API Price utilized in the formulation of products. Sapropterin Hydrochloride API Price is not always fixed or binding as the Sapropterin Hydrochloride Price is obtained through a variety of data sources. The Sapropterin Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Sapropterin Hydrochloride

    Sapropterin Dihydrochloride Manufacturers

    A Sapropterin Dihydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sapropterin Dihydrochloride, including repackagers and relabelers. The FDA regulates Sapropterin Dihydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sapropterin Dihydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Sapropterin Dihydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Sapropterin Dihydrochloride Suppliers

    A Sapropterin Dihydrochloride supplier is an individual or a company that provides Sapropterin Dihydrochloride active pharmaceutical ingredient (API) or Sapropterin Dihydrochloride finished formulations upon request. The Sapropterin Dihydrochloride suppliers may include Sapropterin Dihydrochloride API manufacturers, exporters, distributors and traders.

    click here to find a list of Sapropterin Dihydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Sapropterin Dihydrochloride USDMF

    A Sapropterin Dihydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Sapropterin Dihydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Sapropterin Dihydrochloride DMFs exist exist since differing nations have different regulations, such as Sapropterin Dihydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Sapropterin Dihydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Sapropterin Dihydrochloride USDMF includes data on Sapropterin Dihydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sapropterin Dihydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Sapropterin Dihydrochloride suppliers with USDMF on PharmaCompass.

    Sapropterin Dihydrochloride WC

    A Sapropterin Dihydrochloride written confirmation (Sapropterin Dihydrochloride WC) is an official document issued by a regulatory agency to a Sapropterin Dihydrochloride manufacturer, verifying that the manufacturing facility of a Sapropterin Dihydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Sapropterin Dihydrochloride APIs or Sapropterin Dihydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Sapropterin Dihydrochloride WC (written confirmation) as part of the regulatory process.

    click here to find a list of Sapropterin Dihydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

    Sapropterin Dihydrochloride NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Sapropterin Dihydrochloride as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Sapropterin Dihydrochloride API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Sapropterin Dihydrochloride as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Sapropterin Dihydrochloride and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Sapropterin Dihydrochloride NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Sapropterin Dihydrochloride suppliers with NDC on PharmaCompass.

    Sapropterin Dihydrochloride GMP

    Sapropterin Dihydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Sapropterin Dihydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sapropterin Dihydrochloride GMP manufacturer or Sapropterin Dihydrochloride GMP API supplier for your needs.

    Sapropterin Dihydrochloride CoA

    A Sapropterin Dihydrochloride CoA (Certificate of Analysis) is a formal document that attests to Sapropterin Dihydrochloride's compliance with Sapropterin Dihydrochloride specifications and serves as a tool for batch-level quality control.

    Sapropterin Dihydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Sapropterin Dihydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Sapropterin Dihydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Sapropterin Dihydrochloride EP), Sapropterin Dihydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sapropterin Dihydrochloride USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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