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Chemistry

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Also known as: 869884-78-6, Rx-1741, Rx-103, N-[[(5s)-3-[2-fluoro-4'-[[(1h-1,2,3-triazol-5-ylmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-oxo-5-oxazolidinyl]methyl]acetamide, Rx103, Rx-01_667
Molecular Formula
C22H23FN6O3
Molecular Weight
438.5  g/mol
InChI Key
BTTNOGHPGJANSW-IBGZPJMESA-N
FDA UNII
53PC6LO35W

RX-1741
Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.
1 2D Structure

RX-1741

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[[(5S)-3-[3-fluoro-4-[4-[(2H-triazol-4-ylmethylamino)methyl]phenyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
2.1.2 InChI
InChI=1S/C22H23FN6O3/c1-14(30)25-12-19-13-29(22(31)32-19)18-6-7-20(21(23)8-18)16-4-2-15(3-5-16)9-24-10-17-11-26-28-27-17/h2-8,11,19,24H,9-10,12-13H2,1H3,(H,25,30)(H,26,27,28)/t19-/m0/s1
2.1.3 InChI Key
BTTNOGHPGJANSW-IBGZPJMESA-N
2.1.4 Canonical SMILES
CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)C3=CC=C(C=C3)CNCC4=NNN=C4)F
2.1.5 Isomeric SMILES
CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)C3=CC=C(C=C3)CNCC4=NNN=C4)F
2.2 Other Identifiers
2.2.1 UNII
53PC6LO35W
2.3 Synonyms
2.3.1 MeSH Synonyms

1. N-((3-(2-fluoro-4'-(((1h-1,2,3-triazol-5-ylmethyl)amino)methyl)(1,1'-biphenyl)-4-yl)-2-oxo-5-oxazolidinyl)methyl)acetamide

2. Rx 1741

3. Rx-1741

4. Rx1741

2.3.2 Depositor-Supplied Synonyms

1. 869884-78-6

2. Rx-1741

3. Rx-103

4. N-[[(5s)-3-[2-fluoro-4'-[[(1h-1,2,3-triazol-5-ylmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-oxo-5-oxazolidinyl]methyl]acetamide

5. Rx103

6. Rx-01_667

7. 53pc6lo35w

8. Mmv688327

9. Rx-013

10. Rx1741

11. (s)-n-((3-(4'-((((1h-1,2,3-triazol-5-yl)methyl)amino)methyl)-2-fluoro-[1,1'-biphenyl]-4-yl)-2-oxooxazolidin-5-yl)methyl)acetamide

12. N-[[(5s)-3-[3-fluoro-4-[4-[(2h-triazol-4-ylmethylamino)methyl]phenyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

13. N-{[(5s)-3-(2-fluoro-4'-{[(1h-1,2,3-triazol-5-ylmethyl)amino]methyl}biphenyl-4-yl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide

14. Radezolid [usan]

15. And Rx-01_667

16. Rx-o1_667

17. Radezolid [usan:inn]

18. Unii-53pc6lo35w

19. Rx 1741

20. (5s)-n-[3-(2-fluoro-4'-{[(1h-[1,2,3]triazol-4-ylmethyl)-amino]-methyl)-biphenyl-4-yl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide

21. (5s)-n-[3-(2-fluoro-4'-{[(1h-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-biphenyl-4-yl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide

22. N-(((5s)-3-(2-fluoro-4'-(((1h-1,2,3-triazol-5-ylmethyl)amino)methyl)biphenyl-4-yl)-2-oxo-1,3-oxazolidin-5-yl)methyl)acetamide

23. Rd8

24. Radezolid [inn]

25. Radezolid (usan/inn)

26. Radezolid [who-dd]

27. Chembl455461

28. Schembl1035776

29. Schembl10109382

30. Gtpl10849

31. Dtxsid301007238

32. Ex-a1247

33. Zinc40379938

34. Cs-0688

35. Db12339

36. Rx-01-667

37. Ac-36840

38. Hy-14800

39. D09369

40. A902025

41. Q7280139

42. Acetamide, N-(((5s)-3-(2-fluoro-4'-(((1h-1,2,3-triazol-5-ylmethyl)amino)methyl)(1,1'-biphenyl)-4-yl)-2-oxo-5-oxazolidinyl)methyl)-

43. N-((3-(2-fluoro-4'-(((1h-1,2,3-triazol-5-ylmethyl)amino)methyl)(1,1'-biphenyl)-4-yl)-2-oxo-5-oxazolidinyl)methyl)acetamide

44. N-({(5s)-3-[2-fluoro-4'-({[(1h-1,2,3-triazol-4-yl)methyl]amino}methyl)[1,1'-biphenyl]-4-yl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide

45. N-[[(5s)-3-[3-fluoro-4-[4-[(1h-triazol-5-ylmethylamino)methyl]phenyl]phenyl]-2-oxo-oxazolidin-5-yl]methyl]acetamide

46. N-{ [(5s)-3-(2-fluoro-4'-{[(1h-1,2,3-triazol-5-ylmethyl)amino]methyl}biphenyl-4-yl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 438.5 g/mol
Molecular Formula C22H23FN6O3
XLogP31.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Exact Mass438.18156678 g/mol
Monoisotopic Mass438.18156678 g/mol
Topological Polar Surface Area112 Ų
Heavy Atom Count32
Formal Charge0
Complexity647
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


ABOUT THIS PAGE

Looking for 869884-78-6 / RX-1741 API manufacturers, exporters & distributors?

RX-1741 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of RX-1741 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right RX-1741 manufacturer or RX-1741 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred RX-1741 manufacturer or RX-1741 supplier.

PharmaCompass also assists you with knowing the RX-1741 API Price utilized in the formulation of products. RX-1741 API Price is not always fixed or binding as the RX-1741 Price is obtained through a variety of data sources. The RX-1741 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

RX-1741

Synonyms

869884-78-6, Rx-103, N-[[(5s)-3-[2-fluoro-4'-[[(1h-1,2,3-triazol-5-ylmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-oxo-5-oxazolidinyl]methyl]acetamide, Rx103, Rx-01_667, 53pc6lo35w

Cas Number

869884-78-6

Unique Ingredient Identifier (UNII)

53PC6LO35W

About RX-1741

Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.

RX 1741 Manufacturers

A RX 1741 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of RX 1741, including repackagers and relabelers. The FDA regulates RX 1741 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. RX 1741 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

RX 1741 Suppliers

A RX 1741 supplier is an individual or a company that provides RX 1741 active pharmaceutical ingredient (API) or RX 1741 finished formulations upon request. The RX 1741 suppliers may include RX 1741 API manufacturers, exporters, distributors and traders.

RX 1741 GMP

RX 1741 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of RX 1741 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right RX 1741 GMP manufacturer or RX 1741 GMP API supplier for your needs.

RX 1741 CoA

A RX 1741 CoA (Certificate of Analysis) is a formal document that attests to RX 1741's compliance with RX 1741 specifications and serves as a tool for batch-level quality control.

RX 1741 CoA mostly includes findings from lab analyses of a specific batch. For each RX 1741 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

RX 1741 may be tested according to a variety of international standards, such as European Pharmacopoeia (RX 1741 EP), RX 1741 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (RX 1741 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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