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    Find listed supplier of Ripretinib Active Pharmaceutical Ingredient on PharmaCompass.com

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    Ripretinib

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    Dr. Reddy's Laboratories

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    Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.
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    - About The Company
    Founded in 1984, DRL is well-known for its generic APIs and its track record in drug product development. It is one of the earliest pharma API manufacturers with a diverse portfolio that provides high-quality, low-cost APIs t...
    Founded in 1984, DRL is well-known for its generic APIs and its track record in drug product development. It is one of the earliest pharma API manufacturers with a diverse portfolio that provides high-quality, low-cost APIs to leading pharma companies in 80+ countries. It has 8 USFDA-inspected facilities – 6 in India & 1 each in Mexico & the UK & are inspected by international regulatory authorities on a regular basis. Its facilities are supplemented by formulation facilities that provide a wide range of dosage forms. "Product(s) under patent(s) are offered only for R&D purposes U/S 107A of the Patent Act and not for commercial sale.”
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    Teva API

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    Ripretinib

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    Teva API is a standalone business unit within Teva Pharmaceutical Industries, the world’s largest generic drug manufacturer. Employing over 4,000 professionals at 15 international plant sites and 6 R&D centers, Teva API is ...
    Teva API is a standalone business unit within Teva Pharmaceutical Industries, the world’s largest generic drug manufacturer. Employing over 4,000 professionals at 15 international plant sites and 6 R&D centers, Teva API is a leading international supplier of active pharmaceutical ingredients (APIs) with the industry’s broadest portfolio of over 350 products. Its leadership in cutting-edge development, large-scale production capacity and global support make it an ideal API partner of choice. Over its more than 85 years of existence, Teva API has acquired and established top-rated manufacturing and development facilities around the world.
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    Beijing Sjar Technology Development

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      Beijing Sjar Technology Development Co., Ltd. founded in 2014, it is a high-tech enterprise which specialized in the research and development of active pharmaceutical ingredients and their intermediates, electronic chemical m...
      Beijing Sjar Technology Development Co., Ltd. founded in 2014, it is a high-tech enterprise which specialized in the research and development of active pharmaceutical ingredients and their intermediates, electronic chemical materials and intermediates, large-scale production, sales and services, and provide customized synthetic services according to customer requirements. Sjar-Tech locates in Beijing Economic and Technological Development Zone, has its own R&D and development laboratory. Sjar-Tech has set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience.
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      Looking for 1442472-39-0 / Ripretinib API manufacturers, exporters & distributors?

      Ripretinib manufacturers, exporters & distributors 1

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      PharmaCompass offers a list of Ripretinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ripretinib manufacturer or Ripretinib supplier for your needs.

      Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ripretinib manufacturer or Ripretinib supplier.

      PharmaCompass also assists you with knowing the Ripretinib API Price utilized in the formulation of products. Ripretinib API Price is not always fixed or binding as the Ripretinib Price is obtained through a variety of data sources. The Ripretinib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

      API | Excipient name

      Ripretinib

      Synonyms

      1442472-39-0, Dcc-2618, N-{4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3- yl]-2-fluorophenyl}-n'-phenylurea, Urea, n-[4-bromo-5-[1-ethyl-1,2-dihydro-7-(methylamino)-2-oxo-1,6- naphthyridin-3-yl]-2-fluorophenyl]-n'-phenyl-39-0, Ripretinib free base, Ripretinib [usan]

      Cas Number

      1442472-39-0

      Unique Ingredient Identifier (UNII)

      9XW757O13D

      About Ripretinib

      Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) KIT and platelet-derived growth factor receptor alpha (PDGFR-alpha; PDGFRa), with potential antineoplastic activity. Upon oral administration, ripretinib targets and binds to both wild-type and mutant forms of KIT and PDGFRa specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. This abrogates KIT/PDGFRa-mediated tumor cell signaling and prevents proliferation in KIT/PDGFRa-driven cancers. DCC-2618 also inhibits several other kinases, including vascular endothelial growth factor receptor type 2 (VEGFR2; KDR), angiopoietin-1 receptor (TIE2; TEK), PDGFR-beta and macrophage colony-stimulating factor 1 receptor (FMS; CSF1R), thereby further inhibiting tumor cell growth. KIT and PDGFRa are tyrosine kinase receptors that are upregulated or mutated in a variety of cancer cell types; mutated forms play a key role in the regulation of tumor cell proliferation and resistance to chemotherapy.

      Ripretinib Manufacturers

      A Ripretinib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ripretinib, including repackagers and relabelers. The FDA regulates Ripretinib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ripretinib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

      click here to find a list of Ripretinib manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

      Ripretinib Suppliers

      A Ripretinib supplier is an individual or a company that provides Ripretinib active pharmaceutical ingredient (API) or Ripretinib finished formulations upon request. The Ripretinib suppliers may include Ripretinib API manufacturers, exporters, distributors and traders.

      click here to find a list of Ripretinib suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

      Ripretinib Manufacturers | Traders | Suppliers

      Ripretinib Manufacturers, Traders, Suppliers 1
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      We have 3 companies offering Ripretinib

      Get in contact with the supplier of your choice:

      1. Dr. Reddy's Laboratories
      2. Teva API
      3. Beijing Sjar Technology Development
      Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
      For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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