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Chemistry

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Also known as: 82571-53-7, Ozagrel [inn], Oky-046, (e)-3-(4-((1h-imidazol-1-yl)methyl)phenyl)acrylic acid, Ozagrel free acid, Kct-0809
Molecular Formula
C13H12N2O2
Molecular Weight
228.25  g/mol
InChI Key
SHZKQBHERIJWAO-AATRIKPKSA-N
FDA UNII
L256JB984D

pulmoza
Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.
1 2D Structure

pulmoza

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid
2.1.2 InChI
InChI=1S/C13H12N2O2/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15/h1-8,10H,9H2,(H,16,17)/b6-5+
2.1.3 InChI Key
SHZKQBHERIJWAO-AATRIKPKSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)O
2.1.5 Isomeric SMILES
C1=CC(=CC=C1CN2C=CN=C2)/C=C/C(=O)O
2.2 Other Identifiers
2.2.1 UNII
L256JB984D
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3-(4-(1h-imidazol-1-ylmethyl)phenyl)-2-propenoic Acid

2. 4-(1-imidazoylmethyl)cinnamic Acid

3. Oky 046

4. Oky-046

5. Ozagrel, Monohydrochloride

6. Ozagrel, Monohydrochloride, (e)-isomer

7. Sodium Ozagrel

2.3.2 Depositor-Supplied Synonyms

1. 82571-53-7

2. Ozagrel [inn]

3. Oky-046

4. (e)-3-(4-((1h-imidazol-1-yl)methyl)phenyl)acrylic Acid

5. Ozagrel Free Acid

6. Kct-0809

7. Domenan

8. (e)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic Acid

9. Chembl11662

10. (e)-p-(imidazol-1-ylmethyl)cinnamic Acid

11. L256jb984d

12. 82571-53-7 (free Base)

13. Ozagrel (inn)

14. Ozagrelum [latin]

15. Pulmoza

16. Ozagrelum

17. 3-[4-(1h-imidazol-1-ylmethyl)phenyl]-2e-propenoic Acid

18. 2-propenoic Acid, 3-[4-(1h-imidazol-1-ylmethyl)phenyl]-, (2e)-

19. Unii-l256jb984d

20. Cataclot (tn)

21. Ozagrel,(s)

22. Ozagrel, Oky-046

23. Ozagrel [mi]

24. 2-propenoic Acid, 3-(4-(1h-imidazol-1-ylmethyl)phenyl)-, (e)-

25. 3-[4-(1-imidazolylmethyl)phenyl]-2-propenoic Acid

26. Ozagrel [mart.]

27. Prestwick2_000979

28. Prestwick3_000979

29. Ozagrel [who-dd]

30. Schembl4210

31. Bspbio_001017

32. Bpbio1_001119

33. Gtpl9866

34. Oky046

35. Zinc5389

36. Dtxsid6048547

37. Chebi:92359

38. Chebi:134938

39. Hms2089o14

40. Hms3649m21

41. Hms3884n21

42. Bcp12147

43. Ex-a5744

44. Hy-b0428

45. Bdbm50017896

46. Mfcd00868231

47. S2496

48. Akos015889403

49. Ac-2080

50. Ccg-266782

51. Db12017

52. Ncgc00025195-02

53. As-71327

54. Ls-14195

55. Sbi-0207081.p001

56. Ab00514722

57. Sw197369-5

58. 3-(4-imidazol-1-ylmethyl-phenyl)-acrylic Acid

59. D08327

60. (e)-3-(4-((1h-imidazol-1-yl)methyl)phenyl)

61. Ab00514722-10

62. Ab00514722-12

63. Ab00514722-13

64. Ab00514722_14

65. Ab00514722_15

66. 4-(1h-imidazole-1-ylmethyl)benzenepropenoic Acid

67. 571o537

68. (e)-3-(4-imidazol-1-ylmethyl-phenyl)-acrylic Acid

69. Q-100843

70. Q7116436

71. Sr-01000597793-8

72. 3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic Acid

73. Brd-k19525698-003-01-1

74. Brd-k53061490-003-03-0

75. (e)-3-[4-(1h-imidiazol-1-ylmethyl)phenyl]-2-propenic Acid

76. (2e)-3-[4-(1h-imidazol-1-ylmethyl)phenyl]acrylic Acid

77. (2e)-3-{4-[(1h-imidazol-1-yl)methyl]phenyl}prop-2-enoic Acid

78. (e)-3-[p-(1h-imidazol-1-ylmethyl)phenyl]-2-propenoic Acid

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 228.25 g/mol
Molecular Formula C13H12N2O2
XLogP31.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass228.089877630 g/mol
Monoisotopic Mass228.089877630 g/mol
Topological Polar Surface Area55.1 Ų
Heavy Atom Count17
Formal Charge0
Complexity283
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine Antagonists

Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)


Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)


Fibrinolytic Agents

Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. (See all compounds classified as Fibrinolytic Agents.)


ABOUT THIS PAGE

Looking for 82571-53-7 / pulmoza API manufacturers, exporters & distributors?

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PharmaCompass offers a list of pulmoza API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right pulmoza manufacturer or pulmoza supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred pulmoza manufacturer or pulmoza supplier.

PharmaCompass also assists you with knowing the pulmoza API Price utilized in the formulation of products. pulmoza API Price is not always fixed or binding as the pulmoza Price is obtained through a variety of data sources. The pulmoza Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

pulmoza

Synonyms

82571-53-7, Ozagrel [inn], Oky-046, (e)-3-(4-((1h-imidazol-1-yl)methyl)phenyl)acrylic acid, Ozagrel free acid, Kct-0809

Cas Number

82571-53-7

Unique Ingredient Identifier (UNII)

L256JB984D

About pulmoza

Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.

pulmoza Manufacturers

A pulmoza manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of pulmoza, including repackagers and relabelers. The FDA regulates pulmoza manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. pulmoza API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

pulmoza Suppliers

A pulmoza supplier is an individual or a company that provides pulmoza active pharmaceutical ingredient (API) or pulmoza finished formulations upon request. The pulmoza suppliers may include pulmoza API manufacturers, exporters, distributors and traders.

pulmoza GMP

pulmoza Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of pulmoza GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right pulmoza GMP manufacturer or pulmoza GMP API supplier for your needs.

pulmoza CoA

A pulmoza CoA (Certificate of Analysis) is a formal document that attests to pulmoza's compliance with pulmoza specifications and serves as a tool for batch-level quality control.

pulmoza CoA mostly includes findings from lab analyses of a specific batch. For each pulmoza CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

pulmoza may be tested according to a variety of international standards, such as European Pharmacopoeia (pulmoza EP), pulmoza JP (Japanese Pharmacopeia) and the US Pharmacopoeia (pulmoza USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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