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Chemistry

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Also known as: Nicotinamide adenine dinucleotide, Nad+, Enzopride, Diphosphopyridine nucleotide, 53-84-9, Adenine-nicotinamide dinucleotide
Molecular Formula
C21H28N7O14P2+
Molecular Weight
664.4  g/mol
InChI Key
BAWFJGJZGIEFAR-NNYOXOHSSA-O

Beta Nicotinamide Adenine Dinucleotide
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
1 2D Structure

Beta Nicotinamide Adenine Dinucleotide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
2.1.2 InChI
InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
2.1.3 InChI Key
BAWFJGJZGIEFAR-NNYOXOHSSA-O
2.1.4 Canonical SMILES
C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
2.1.5 Isomeric SMILES
C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Adenine Dinucleotide, Dihydronicotinamide

2. Coenzyme I

3. Dihydronicotinamide Adenine Dinucleotide

4. Dinucleotide, Dihydronicotinamide Adenine

5. Dinucleotide, Nicotinamide-adenine

6. Diphosphopyridine Nucleotide

7. Dpn

8. Nad

9. Nadh

10. Nadide

11. Nicotinamide Adenine Dinucleotide

12. Nicotinamide-adenine Dinucleotide

13. Nucleotide, Diphosphopyridine

2.2.2 Depositor-Supplied Synonyms

1. Nicotinamide Adenine Dinucleotide

2. Nad+

3. Enzopride

4. Diphosphopyridine Nucleotide

5. 53-84-9

6. Adenine-nicotinamide Dinucleotide

7. Nad

8. Nadidum [inn-latin]

9. Nadida [inn-spanish]

10. Nad(+)

11. Chebi:15846

12. [[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2r,3s,4r,5r)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl Hydrogen Phosphate

13. 151411-04-0

14. Nicotinamide-adenine Dinucleotide

15. Brn 3584133

16. Sr-05000001677

17. Nadide [usan:ban:inn:jan]

18. Nad Cation

19. [[(2r,3s,4r,5r)-5-[(3r)-3-aminocarbonyl-3,4-dihydro-2h-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl Phosphate

20. 121053-11-0

21. Naj

22. Txe

23. Spectrum_000973

24. Nicotinamide Adenine Dinucleotide (nad+)

25. [[(2~{r},3~{s},4~{r},5~{r})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-4-[[5-[4-cyano-2-[(~{e})-hydroxyiminomethyl]phenoxy]-1-oxidanyl-3~{h}-2,1$l^{4}-benzoxaborol-1-yl]oxy]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl Hydrogen Phosphate

26. 9jm

27. Adenosine 5'-(trihydrogen Diphosphate), P'-5'-ester With 3-(aminocarbonyl)-1-beta-d-ribofuranosylpyridinium, Inner Salt

28. Prestwick3_000741

29. Pyridinium, 3-carbamoyl-1-beta-d-ribofuranosyl-, Hydroxide, 5'-ester With Adenosine 5'-5'-(trihydrogen Pyrophosphate), Inner Salt

30. Spectrum2_001056

31. Spectrum3_000511

32. Spectrum4_000065

33. Spectrum5_001291

34. Bmse000053

35. Nadide (jan/usan/inn)

36. Bspbio_000722

37. Bspbio_002061

38. Kbiogr_000589

39. Kbioss_001453

40. Divk1c_000189

41. Spbio_001012

42. Bpbio1_000796

43. Chembl3039307

44. Schembl14478781

45. Kbio1_000189

46. Kbio2_001453

47. Kbio2_004021

48. Kbio2_006589

49. Kbio3_001561

50. Ninds_000189

51. Zinc8214766

52. Idi1_000189

53. 65085-09-8

54. C00003

55. D00002

56. 036d253

57. Sr-05000001677-1

58. Sr-05000001677-3

59. Brd-a11132253-001-01-7

60. Q26987253

61. 1-[5-o-[(5'-adenylyloxy)phosphonyl]-beta-d-ribofuranosyl]-3-(aminocarbonyl)pyridinium

62. Coconut Oil, Polymer With Benzoic Acid, Glycerol, Pentaerythritol And Phthalic Anhydride

63. 865-05-4

64. Adenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-d-ribitol-5-yl] Dihydrogen Diphosphate}

2.3 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 664.4 g/mol
Molecular Formula C21H28N7O14P2+
XLogP3-5.9
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count18
Rotatable Bond Count11
Exact Mass664.11694759 g/mol
Monoisotopic Mass664.11694759 g/mol
Topological Polar Surface Area318 Ų
Heavy Atom Count44
Formal Charge1
Complexity1130
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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A30,A.I.E"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745433000,"product":"BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE(B-NADH) (IMPORT UNDER100% EOU)BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE (B-NADH)","address":"Koyikkalethu Veeyapuram","city":"Alappuzha","supplier":"HUNAN FUBAO BIOCHEMICAL TRADE COLTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"MOLECULES BIO LABS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"845","totalValueFC":"12793.2","currency":"USD","unitRateINR":"73008","date":"24-Apr-2025","totalValueINR":"1095120","totalValueInUsd":"12793.2","indian_port":"Cochin Air","hs_no":"29362990","bill_no":"9668215","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"FIRST FLOOR, BUILDING 1101010, HUMAN FLAG BIO-TECHNOLOGY CO.,LTD.. 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30-Apr-2025
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ABOUT THIS PAGE

Looking for 53-84-9 / Nicotinamide Adenine Dinucleotide API manufacturers, exporters & distributors?

Nicotinamide Adenine Dinucleotide manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Nicotinamide Adenine Dinucleotide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Nicotinamide Adenine Dinucleotide manufacturer or Nicotinamide Adenine Dinucleotide supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Nicotinamide Adenine Dinucleotide manufacturer or Nicotinamide Adenine Dinucleotide supplier.

PharmaCompass also assists you with knowing the Nicotinamide Adenine Dinucleotide API Price utilized in the formulation of products. Nicotinamide Adenine Dinucleotide API Price is not always fixed or binding as the Nicotinamide Adenine Dinucleotide Price is obtained through a variety of data sources. The Nicotinamide Adenine Dinucleotide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Nicotinamide Adenine Dinucleotide

Synonyms

Nad+, Enzopride, Diphosphopyridine nucleotide, 53-84-9, Adenine-nicotinamide dinucleotide, Nad

Cas Number

53-84-9

About Nicotinamide Adenine Dinucleotide

A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)

Nad Manufacturers

A Nad manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nad, including repackagers and relabelers. The FDA regulates Nad manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nad API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Nad manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Nad Suppliers

A Nad supplier is an individual or a company that provides Nad active pharmaceutical ingredient (API) or Nad finished formulations upon request. The Nad suppliers may include Nad API manufacturers, exporters, distributors and traders.

click here to find a list of Nad suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Nad USDMF

A Nad DMF (Drug Master File) is a document detailing the whole manufacturing process of Nad active pharmaceutical ingredient (API) in detail. Different forms of Nad DMFs exist exist since differing nations have different regulations, such as Nad USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Nad DMF submitted to regulatory agencies in the US is known as a USDMF. Nad USDMF includes data on Nad's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Nad USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Nad suppliers with USDMF on PharmaCompass.

Nad NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Nad as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Nad API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Nad as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Nad and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Nad NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Nad suppliers with NDC on PharmaCompass.

Nad GMP

Nad Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Nad GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Nad GMP manufacturer or Nad GMP API supplier for your needs.

Nad CoA

A Nad CoA (Certificate of Analysis) is a formal document that attests to Nad's compliance with Nad specifications and serves as a tool for batch-level quality control.

Nad CoA mostly includes findings from lab analyses of a specific batch. For each Nad CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Nad may be tested according to a variety of international standards, such as European Pharmacopoeia (Nad EP), Nad JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nad USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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