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Chemistry

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Also known as: (-)-menthone, 14073-97-3, L-menthone, Trans-menthone, (2s,5r)-2-isopropyl-5-methylcyclohexanone, P-menthone
Molecular Formula
C10H18O
Molecular Weight
154.25  g/mol
InChI Key
NFLGAXVYCFJBMK-BDAKNGLRSA-N
FDA UNII
5F709W4OG4

Menthone
Menthone is a metabolite found in or produced by Saccharomyces cerevisiae.
1 2D Structure

Menthone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-one
2.1.2 InChI
InChI=1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3/t8-,9+/m1/s1
2.1.3 InChI Key
NFLGAXVYCFJBMK-BDAKNGLRSA-N
2.1.4 Canonical SMILES
CC1CCC(C(=O)C1)C(C)C
2.1.5 Isomeric SMILES
C[C@@H]1CC[C@H](C(=O)C1)C(C)C
2.2 Other Identifiers
2.2.1 UNII
5F709W4OG4
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. (-)-menthone

2. 14073-97-3

3. L-menthone

4. Trans-menthone

5. (2s,5r)-2-isopropyl-5-methylcyclohexanone

6. P-menthone

7. L-menthan-3-one

8. Neomenthone

9. Menthone Racemic

10. Trans-menthan-3-one

11. 89-80-5

12. Trans-p-menthan-3-one

13. (1r,4s)-(-)-p-menthan-3-one

14. Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2s,5r)-

15. Dl-menthone

16. P-menthan-3-one, Trans-

17. Fema No. 2667

18. (2s,5r)-5-methyl-2-(propan-2-yl)cyclohexanone

19. (-)-(2s,5r)-menthone

20. (1r,4s)-p-menthan-3-one

21. (2s,5r)-5-methyl-2-(1-methylethyl)cyclohexanone

22. (2s,5r)-5-methyl-2-propan-2-ylcyclohexan-1-one

23. (2s-trans)-5-methyl-2-(1-methylethyl)cyclohexanone

24. Cyclohexanone, 5-methyl-2-(1-methylethyl)-, Trans-

25. (-)-(1r,4s)-menthone

26. (2s,5r)-5-methyl-2-(1-methylethyl)-cyclohexanone

27. Chebi:15410

28. (-)-5-methyl-2-(1-methylethyl)cyclohexanone

29. 5f709w4og4

30. Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2s-trans)-

31. Dsstox_cid_24384

32. Dsstox_rid_80188

33. Dsstox_gsid_44384

34. Menthone (natural)

35. P-menthan-3-one Racemic

36. L-p-menthan-3-one

37. (dl)-menthone

38. 5-methyl-2-(1-methylethyl)cyclohexanone

39. Cas-14073-97-3

40. Ccris 5747

41. Hsdb 1268

42. P-menthan-3-one, Dl-

43. Einecs 201-941-1

44. Einecs 214-049-2

45. Unii-9nh5j4v8fn

46. Menthon

47. Unii-5f709w4og4

48. Ai3-11106

49. Menthone G

50. Trans-p-menthone

51. 1-menthone

52. (-)menthone

53. 5-methyl-2-(1-methylethyl)cyclohexanone, Trans-

54. Ncgc00095606-01

55. Cyclohexan-1-one, 2-isopropyl-5-methyl-, Racemic

56. Einecs 237-926-1

57. Mfcd00001634

58. Menthan-3-one, Trans

59. Spectrum_001299

60. Rel-(2r,5s)-2-isopropyl-5-methylcyclohexanone

61. (-)-menthone,(s)

62. Menthone [fhfi]

63. Specplus_000437

64. Menthone, L-

65. L-menthone [mi]

66. Spectrum2_000691

67. Spectrum3_001272

68. Spectrum4_001648

69. Spectrum5_000495

70. (2s,5r)-2-isopropyl-5-methyl-cyclohexanone

71. Bmse000375

72. (-)-menthone, 90%

73. Ec 237-926-1

74. 9nh5j4v8fn

75. Schembl21709

76. Bspbio_002864

77. Kbiogr_002115

78. Kbioss_001779

79. Menthone, (-)-

80. Spectrum300564

81. Divk1c_006533

82. Spbio_000841

83. (1s)-trans-p-menthan-3-one

84. (-)-menthone [fcc]

85. (2s,5r)-5-methyl-2-(propan-2-yl)cyclohexan-1-one

86. Chembl276311

87. Dtxsid2044478

88. Dtxsid3044384

89. Kbio1_001477

90. Kbio2_001779

91. Kbio2_004347

92. Kbio2_006915

93. Kbio3_002364

94. Cyclohexanone, 5-methyl-2-(1-methylethyl)-, Trans-(+/-)-

95. Zinc967796

96. (-)-menthone, Analytical Standard

97. Hy-n7916

98. Tox21_111510

99. Tox21_302153

100. Ccg-38562

101. Mfcd00136033

102. Akos006343213

103. Tox21_111510_1

104. Lmpr0102090004

105. Sdccgmls-0066582.p001

106. 2-isopropyl-5-methylcyclohexanone, Trans

107. Ncgc00095606-02

108. Ncgc00178425-01

109. Ncgc00255957-01

110. As-17440

111. (2s,5r)2-isopropyl-5-methylcyclohexanone

112. Cs-0138798

113. 1-methyl-4-isopropylcyclohexan-3-one

114. C00843

115. (2s,5r)-2-isopropyl-5-methylcyclohexan-1-one

116. (2s, 5r)-trans-2-isopropyl-5-methylcyclohexanone

117. Q424902

118. Sr-05000002387

119. 5-methyl-2-(1-methylethyl)-(2s,5r)-cyclohexanone

120. L-menthone, Mixture Of Isomers, >=96%, Fcc, Fg

121. Sr-05000002387-1

122. W-108194

123. 5-methyl-2-(1-methylethyl)-(2s-trans)-cyclohexanone

124. (-)-menthone, Primary Pharmaceutical Reference Standard

125. Cyclohexanone, 5-methyl-2-(1-methylethyl)-, Trans-(.+/-.)-

126. 1/c10h18o/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9h,4-6h2,1-3h3/t8-,9+/m1/s

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 154.25 g/mol
Molecular Formula C10H18O
XLogP32.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass154.135765193 g/mol
Monoisotopic Mass154.135765193 g/mol
Topological Polar Surface Area17.1 Ų
Heavy Atom Count11
Formal Charge0
Complexity149
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Metabolism/Metabolites

...KETONES (EG CARVONE & MENTHONE) ARE REDUCED TO SECONDARY ALCOHOLS WHICH ARE THEN EXCRETED AS GLUCURONIDES. MENTHONE, ASYMMETRIC REDUCTION /TO/ NEO-MENTHOL, GLUCURONIDE CONJUGATION /TO/ MENTHYL GLUCURONIDE.

Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 149


ABOUT THIS PAGE

Looking for 14073-97-3 / Menthone API manufacturers, exporters & distributors?

Menthone manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Menthone API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Menthone manufacturer or Menthone supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Menthone manufacturer or Menthone supplier.

PharmaCompass also assists you with knowing the Menthone API Price utilized in the formulation of products. Menthone API Price is not always fixed or binding as the Menthone Price is obtained through a variety of data sources. The Menthone Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Menthone

Synonyms

(-)-menthone, 14073-97-3, L-menthone, Trans-menthone, (2s,5r)-2-isopropyl-5-methylcyclohexanone, P-menthone

Cas Number

14073-97-3

Unique Ingredient Identifier (UNII)

5F709W4OG4

About Menthone

Menthone is a metabolite found in or produced by Saccharomyces cerevisiae.

Menthone Manufacturers

A Menthone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Menthone, including repackagers and relabelers. The FDA regulates Menthone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Menthone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Menthone Suppliers

A Menthone supplier is an individual or a company that provides Menthone active pharmaceutical ingredient (API) or Menthone finished formulations upon request. The Menthone suppliers may include Menthone API manufacturers, exporters, distributors and traders.

Menthone GMP

Menthone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Menthone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Menthone GMP manufacturer or Menthone GMP API supplier for your needs.

Menthone CoA

A Menthone CoA (Certificate of Analysis) is a formal document that attests to Menthone's compliance with Menthone specifications and serves as a tool for batch-level quality control.

Menthone CoA mostly includes findings from lab analyses of a specific batch. For each Menthone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Menthone may be tested according to a variety of international standards, such as European Pharmacopoeia (Menthone EP), Menthone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Menthone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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