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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS

CEP/COS Certifications

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JDMF

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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FINISHED DOSAGE FORMULATIONS

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PATENTS & EXCLUSIVITIES

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US Patents

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Chemistry

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Also known as: 214047-00-4, Matrixyl, (2s,5s,8s,11s,14s)-5,14-bis(4-aminobutyl)-8,11-bis((r)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oic acid, N2-(1-oxohexadecyl)-l-lysyl-l-threonyl-l-threonyl-l-lysyl-l-serine, Palmitoyl pentapeptide-3, Palmitoyl pentapeptide 4
Molecular Formula
C39H75N7O10
Molecular Weight
802.1  g/mol
InChI Key
WSGCRSMLXFHGRM-DEVHWETNSA-N
FDA UNII
KK181SM5JG

Matrixyl
1 2D Structure

Matrixyl

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[(2S)-6-amino-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid
2.1.2 InChI
InChI=1S/C39H75N7O10/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-23-32(50)42-29(21-17-19-24-40)36(52)45-34(28(3)49)38(54)46-33(27(2)48)37(53)43-30(22-18-20-25-41)35(51)44-31(26-47)39(55)56/h27-31,33-34,47-49H,4-26,40-41H2,1-3H3,(H,42,50)(H,43,53)(H,44,51)(H,45,52)(H,46,54)(H,55,56)/t27-,28-,29+,30+,31+,33+,34+/m1/s1
2.1.3 InChI Key
WSGCRSMLXFHGRM-DEVHWETNSA-N
2.2 Other Identifiers
2.2.1 UNII
KK181SM5JG
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Pal-kttks

2. Palmitoyl-lysyl-threonyl-threonyl-lysyl-serine

2.3.2 Depositor-Supplied Synonyms

1. 214047-00-4

2. Matrixyl

3. (2s,5s,8s,11s,14s)-5,14-bis(4-aminobutyl)-8,11-bis((r)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oic Acid

4. N2-(1-oxohexadecyl)-l-lysyl-l-threonyl-l-threonyl-l-lysyl-l-serine

5. Palmitoyl Pentapeptide-3

6. Palmitoyl Pentapeptide 4

7. Palmitoyl Pentapeptide

8. (2s)-2-[[(2s)-6-amino-2-[[(2s,3r)-2-[[(2s,3r)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic Acid

9. Pal-kttks

10. Oristar Popp

11. Mfcd09842091

12. Lipopentapeptide 3

13. C39h75n7o10

14. Palmitoyl Pentapeptide?

15. Wsgcrsmlxfhgrm-devhwetnsa-n

16. Pal-lys-thr-thr-lys-ser

17. Kk181sm5jg

18. Schembl352420

19. Chembl451881

20. Hy-p0045

21. Akos027326911

22. As-72359

23. Cs-0005656

24. C74034

25. A902886

26. (2s)-2-[(2s)-6-amino-2-[(2s,3r)-2-[(2s,3r)-2-[(2s)-6-amino-2-hexadecanamidohexanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]hexanamido]-3-hydroxypropanoic Acid

27. (2s,5s,8s,11s,14s)-5,14-bis(4-aminobutyl)-8,11-bis((r)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oic Acid (palmitoyl-lys-thr-thr-lys-ser-oh)

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 802.1 g/mol
Molecular Formula C39H75N7O10
XLogP30.8
Hydrogen Bond Donor Count11
Hydrogen Bond Acceptor Count12
Rotatable Bond Count35
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area296
Heavy Atom Count56
Formal Charge0
Complexity1130
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API SUPPLIERS

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01

Faran Shimi Pharmaceutical

Iran

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothFaran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

Flag Iran
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Faran Shimi Pharmaceutical

02

Macale Biotechnology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AAPS National Biotech
Not Confirmed
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Macale Biotechnology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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AAPS National Biotech
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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03

Tianjin YR Chemspec Technology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AAPS National Biotech
Not Confirmed
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Tianjin YR Chemspec Technology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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AAPS National Biotech
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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04

Natural Biolabs

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AAPS National Biotech
Not Confirmed
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Natural Biolabs

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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AAPS National Biotech
Not Confirmed
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05

Suzhou Pharmaceutical Technology C...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AAPS National Biotech
Not Confirmed
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Suzhou Pharmaceutical Technology C...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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AAPS National Biotech
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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06

Suzhou Pharmaceutical Technology C...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AAPS National Biotech
Not Confirmed
arrow

Suzhou Pharmaceutical Technology C...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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AAPS National Biotech
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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07

Hangzhou Longshine Bio-Tech

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AAPS National Biotech
Not Confirmed
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Hangzhou Longshine Bio-Tech

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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AAPS National Biotech
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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08

Trulux

Australia

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AAPS National Biotech
Not Confirmed
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Trulux

Australia

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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AAPS National Biotech
Not Confirmed
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Listed Suppliers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothFaran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

Flag Iran
Digital Content Digital Content

Matrixyl

About the Company : Faran Shimi Pharmaceutical Company, established in 2001 and affiliated with Golrang Pharmaceutical Investment Co, manufactures high-quality Active Pharmaceutical Ingredients (APIs)...

Faran Shimi Pharmaceutical Company, established in 2001 and affiliated with Golrang Pharmaceutical Investment Co, manufactures high-quality Active Pharmaceutical Ingredients (APIs) and finished dosage forms. For the past three years, the company focused on extracting alkaloid opiates, controlled substances, and narcotics. The APIs are widely used by major pharmaceutical companies nationwide and exported to the Middle East. All production adheres to local GMP standards in an SOP-driven environment with modern systems and utilities, ensuring the highest quality and safety.
Faran Shimi Pharmaceutical

02

Arvo
Not Confirmed
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Arvo
Not Confirmed

Matrixyl

About the Company : Established in 2011 and situated in Hangzhou, Zhejiang, China, Hangzhou Longshine Bio-Tech CO., Ltd is dedicated to providing services for pharmaceutical and chemical products, cat...

Established in 2011 and situated in Hangzhou, Zhejiang, China, Hangzhou Longshine Bio-Tech CO., Ltd is dedicated to providing services for pharmaceutical and chemical products, catering to both export and import markets. The company consists of two primary business departments: the Professional Sourcing/Product Team and the Quality Team. Backed by experienced partners, Longshine has evolved into a trustworthy supplier of high-quality products and received ISO9001:2008 certification in 2017.
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03

Arvo
Not Confirmed
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Arvo
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Matrixyl

About the Company : Xi'an Macale Biotechnology Co., Ltd., established in 2012, is a high-tech enterprise specializing in R&D, production, and sales. Located in Xi'an, Shaanxi, it covers 35,000 sqm wit...

Xi'an Macale Biotechnology Co., Ltd., established in 2012, is a high-tech enterprise specializing in R&D, production, and sales. Located in Xi'an, Shaanxi, it covers 35,000 sqm with a 20,000 sqm building. The company benefits from rich plant resources in the mountainous regions of southern Shaanxi, focusing on Chinese medicinal materials and intermediates. Macale Bio has three multifunctional extraction and purification lines, a GMP production line, a pilot line, and a fully equipped laboratory with advanced detection equipment.
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04

Arvo
Not Confirmed
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Arvo
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Matrixyl

About the Company : Naturabio Laboratories Ltd. is a leading supply chain management company specializing in Active Pharmaceutical Ingredients (APIs) and Intermediates. Established with a focus on ser...

Naturabio Laboratories Ltd. is a leading supply chain management company specializing in Active Pharmaceutical Ingredients (APIs) and Intermediates. Established with a focus on serving the pharmaceutical industry, we provide comprehensive solutions that include GMP consultation, customized project development, and licensing of Finished Dosage Forms.
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05

Arvo
Not Confirmed
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Arvo
Not Confirmed

Matrixyl

About the Company : Suzhou Pharmaceutical Technology Co.,Ltd Is A Corporation Which Engaged In The R&D And Manufacture Of Chemicals, Pharmaceuticals And Intermediates. We Have Earned Ourselves A Good ...

Suzhou Pharmaceutical Technology Co.,Ltd Is A Corporation Which Engaged In The R&D And Manufacture Of Chemicals, Pharmaceuticals And Intermediates. We Have Earned Ourselves A Good Reputation At Home And Abroad With Advanced Technology, Standardized Management And Well Established Service Systerm. We Have Developed To A Very Famous Group Corporation Enterprise In Chemical Industry Step By Step. Over The Past Years, We Are Engaged In The Exporting Business, Our Products Have Reached Far To The USA, Europe, South Asia, Middle East And So On, Also Our Company Has Established Long Term And Stable Business Relationships With Our Customers.
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06

Arvo
Not Confirmed
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Arvo
Not Confirmed

Matrixyl

About the Company : Suzhou Pharmaceutical Technology Co.,Ltd Is A Corporation Which Engaged In The R&D And Manufacture Of Chemicals, Pharmaceuticals And Intermediates. We Have Earned Ourselves A Good ...

Suzhou Pharmaceutical Technology Co.,Ltd Is A Corporation Which Engaged In The R&D And Manufacture Of Chemicals, Pharmaceuticals And Intermediates. We Have Earned Ourselves A Good Reputation At Home And Abroad With Advanced Technology, Standardized Management And Well Established Service Systerm. We Have Developed To A Very Famous Group Corporation Enterprise In Chemical Industry Step By Step. Over The Past Years, We Are Engaged In The Exporting Business, Our Products Have Reached Far To The USA, Europe, South Asia, Middle East And So On, Also Our Company Has Established Long Term And Stable Business Relationships With Our Customers.
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07

Arvo
Not Confirmed
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Arvo
Not Confirmed

Matrixyl

About the Company : YR Chemspec® is a qualified manufacturer and supplier, audited and approved by SGS and ISO, adhering strictly to the ISO 9001:2015 Quality Management System. Committed to fosterin...

YR Chemspec® is a qualified manufacturer and supplier, audited and approved by SGS and ISO, adhering strictly to the ISO 9001:2015 Quality Management System. Committed to fostering innovation, we collaborate with leading universities and institutes to drive high-quality development in the industry. Our key industry-university-research projects focus on advancing scientific and technological breakthroughs in areas such as Vitamin Derivatives, Fermented Actives, Plant Extracts, PVP Polymers, and Polyquaternium series products.
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08

Trulux

Australia
Arvo
Not Confirmed
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Trulux

Australia
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Arvo
Not Confirmed

Matrixyl

About the Company : Trulux, Australia's leading contract manufacturer of skincare, haircare, health, and beauty products. We are dedicated to creating high-quality formulations that meet the unique ne...

Trulux, Australia's leading contract manufacturer of skincare, haircare, health, and beauty products. We are dedicated to creating high-quality formulations that meet the unique needs of our clients. Whether you're looking for custom product development, manufacturing, or private label solutions
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