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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: S-adenosylmethionine, Ademetionine, Adomet, 485-80-3, Donamet, S-adenosyl methionine
Molecular Formula
C15H23N6O5S+
Molecular Weight
399.4  g/mol
InChI Key
MEFKEPWMEQBLKI-AIRLBKTGSA-O

Ademetionine
Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
1 2D Structure

Ademetionine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium
2.1.2 InChI
InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7-,8+,10+,11+,14+,27?/m0/s1
2.1.3 InChI Key
MEFKEPWMEQBLKI-AIRLBKTGSA-O
2.1.4 Canonical SMILES
C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
2.1.5 Isomeric SMILES
C[S+](CC[C@@H](C(=O)O)N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Ademetionine

2. Adomet

3. Fo 1561

4. Fo-1561

5. Fo1561

6. Gumbaral

7. S Adenosyl L Methionine

8. S Adenosylmethionine

9. S Adenosylmethionine Sulfate Tosylate

10. S Amet

11. S-adenosylmethionine

12. S-adenosylmethionine Sulfate Tosylate

13. Sam-e

14. Samyr

2.2.2 Depositor-Supplied Synonyms

1. S-adenosylmethionine

2. Ademetionine

3. Adomet

4. 485-80-3

5. Donamet

6. S-adenosyl Methionine

7. Adenosylmethionine

8. Chebi:15414

9. Active Methionine

10. Chembl224120

11. Methionine, S-adenosyl-

12. (r)-s-adenosyl-l-methionine

13. (s)-s-adenosyl-l-methionine

14. S-(5'-deoxyadenosin-5'-yl)-l-methionine

15. Adenosine, 5'-[[(3s)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-

16. S-adenosyl-methionine

17. (s,s)-adomet

18. [(3s)-3-amino-3-carboxypropyl]-[[(2s,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium

19. S-(5'-adenosyl)-l-methionine

20. 2-s-adenosyl-l-methionine

21. Sam

22. Ncgc00167546-02

23. S-adenosyl-l-methionine Disulphate Tosylate

24. Ademethionine

25. Adome

26. Adenosine, 5'-((l-3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-, Hydroxide, Inner Salt

27. Bmse000059

28. Schembl25177

29. Schembl59293

30. Schembl599664

31. Gtpl4786

32. Chebi:33440

33. Chebi:33442

34. Dtxsid20110014

35. S-(5'-adenosyl)methionine-s-ium

36. Zinc4214738

37. Zinc4228231

38. Bdbm50513996

39. Akos025310126

40. Am84912

41. Ncgc00167546-01

42. S-adenosylmethionine (protonated Carboxy Group)

43. Q27115647

44. Q27115649

45. Q56071634

46. 5'-deoxyadenosine-5'-l-methionine Disulfate Ditosylate

47. 5'-deoxyadenosine-5'-l-methionine Disulphate Ditosylate

48. (3s)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine

49. [(3s)-3-amino-3-carboxypropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonium

50. 5'-[[(3s)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine

51. (3s)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine, Inner Salt

52. (r)-[(3s)-3-amino-3-carboxypropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonium

53. (s)-[(3s)-3-amino-3-carboxypropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonium

54. [(3r)-3-amino-3-carboxypropyl]({[(2s,3s,4r,5r)-5-(6-amino-9h-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium

55. [(3s)-3-amino-3-carboxypropyl]({[(2s,3s,4r,5r)-5-(6-amino-9h-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium

56. [1-(adenin-9-yl)-1,5-dideoxy-beta-d-ribofuranos-5-yl][(3s)-3-amino-3-carboxypropyl](methyl)sulfonium

57. 5 Inverted Exclamation Marka-[[(3s)-3-amino-3-carboxypropyl]methylsulfonio]-5 Inverted Exclamation Marka-deoxyadenosine

58. 5invertedexclamationmarka-[[(3s)-3-amino-3-carboxypropyl]methylsulfonio]-5invertedexclamationmarka-deoxyadenosine

2.3 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 399.4 g/mol
Molecular Formula C15H23N6O5S+
XLogP3-3.5
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass399.14506403 g/mol
Monoisotopic Mass399.14506403 g/mol
Topological Polar Surface Area184 Ų
Heavy Atom Count27
Formal Charge1
Complexity533
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

A - Alimentary tract and metabolism

A16 - Other alimentary tract and metabolism products

A16A - Other alimentary tract and metabolism products

A16AA - Amino acids and derivatives

A16AA02 - Ademetionine


Listed Suppliers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothZhejiang Hengkang Pharm Group is a dynamic pharmaceutical entity, spanning drug research, large-scale production, and global marketing.

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Digital Content Digital Content

Ademetionine

About the Company : Established in 2004 and headquartered in Hangzhou, Hengkang established multiple factories, research and sales centers in Zhejiang, Shandong, and Henan. With facilities conforming ...

Established in 2004 and headquartered in Hangzhou, Hengkang established multiple factories, research and sales centers in Zhejiang, Shandong, and Henan. With facilities conforming to global API standards, along with professional R&D and marketing teams, Hengkang’s operations span major pharmaceutical markets such as China, Europe, the CIS region, Japan, and South Korea. Hengkang has established long-term and stable relationships with nearly 70 countries overseas and hundreds of domestic enterprises. Note: Product(s) under patent(s) are offered only for R&D purposes as per the Patent Act & not for commercial sale.
Zhejiang Hengkang Pharmaceutical

02

Bioquim

Spain
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBioquim: An European GMP-certified company manufacturing bulk APIs, specializing in sterile lyophilization and chemical synthesis.

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Digital Content Digital Content

S-Adenosyl Methionine

About the Company : Bioquim is a European company specializing in bulk oral and sterile APIs for the pharmaceutical industry. With over 40 years of experience, the company supplies corticosteroids, pe...

Bioquim is a European company specializing in bulk oral and sterile APIs for the pharmaceutical industry. With over 40 years of experience, the company supplies corticosteroids, peptides, amino acids, penicillin derivatives, non-penicillin antibiotics, and HPAPIs for human and veterinary use. Bioquim operates GMP-compliant, state-of-the-art facilities and also offers Custom Synthesis and Contract Manufacturing services, supported by expertise in chemical synthesis and sterile API lyophilization. Note: Product(s) under patent(s) are offered only for R&D purposes as per the Patent Act & not for commercial sale.
Bioquim

03

Enomark

India
BePharma
Not Confirmed
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Enomark

India
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BePharma
Not Confirmed

S-Adenosyl Methionine

About the Company : ENOMARK Group of Companies stands as a prominent Contract Manufacturer, boasting a cutting-edge manufacturing facility in Ahmadabad (Gujarat) that complies with WHO-GMP standards. ...

ENOMARK Group of Companies stands as a prominent Contract Manufacturer, boasting a cutting-edge manufacturing facility in Ahmadabad (Gujarat) that complies with WHO-GMP standards. ENOMARK is known for its extensive product portfolio, which includes Tablets, Capsules, Dry Syrups, Protein Powders, Soft Gelatin Capsules, Gummy Candy, Liquid Orals, Oral Spray, Effervescent Tablets, Sachets and Oil.
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04

BePharma
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BePharma
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S-adenosyl-L-methionine

About the Company : At Gnosis by Lesaffre, we harness the power of microorganisms to transform compounds into usable nutritional actives, probiotics, and nutritional yeasts that benefit human wellbein...

At Gnosis by Lesaffre, we harness the power of microorganisms to transform compounds into usable nutritional actives, probiotics, and nutritional yeasts that benefit human wellbeing. Our process is natural, is sustainable, and will shape the future of the industry. Our process is called biotransformation. We strive to create a world that moves better, digests better, ages better, feels better, and, ultimately, lives better thanks to microorganisms and biotransformation
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05

Samoh Pharm Co.Ltd

South Korea
BePharma
Not Confirmed
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Samoh Pharm Co.Ltd

South Korea
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BePharma
Not Confirmed

S-Adenosyl Methionine

About the Company : SAM-OH is the most important and reliable organization for import and export business in Korea. We are grateful to be your worldwide partner in fields of Pharmaceuticals, Veterinar...

SAM-OH is the most important and reliable organization for import and export business in Korea. We are grateful to be your worldwide partner in fields of Pharmaceuticals, Veterinary Pharmaceuticals, Functional Foods, Cosmetics and Fine Chemicals.Since foundation of the organization in 1983, SAM-OH has devoted itself to adopting, developing, research coordinating, marketing, trading, wholesaling and producing goods in related area mainly for human health and beauty which are the wishes of human being.Accomplishing our objectives, our organization has been to find partners all over the world, and this creative and innovative work will be continued.
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06

BePharma
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BePharma
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Ademetionine

About the Company : Sandoo Pharmaceuticals and Chemcials Co.,Ltd was established in 2009, with a young and active team, located in Ningbo, China. Specializes in exporting and importing pharmaceutica...

Sandoo Pharmaceuticals and Chemcials Co.,Ltd was established in 2009, with a young and active team, located in Ningbo, China. Specializes in exporting and importing pharmaceutical intermediates and chemical products as well as active pharmaceutical ingredients.
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07

BePharma
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BePharma
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S-ADENOSYL-L-METHIONINE DISULFATE TOSYLATE

About the Company : Shandong Luning Pharmaceutical Co., Ltd. is part of Shandong Luning Group. Founded in 2008, it is a well-known pharmaceutical and chemical production company. Its main products inc...

Shandong Luning Pharmaceutical Co., Ltd. is part of Shandong Luning Group. Founded in 2008, it is a well-known pharmaceutical and chemical production company. Its main products include finished drugs, APIs, pharmaceutical intermediates, bioengineering, daily chemicals,water treatment chemical engineering, fine chemicals and chemical raw materials. The company occupies 20 million square meters, the total assets of 84 million US dollars, employs more than 200 people, we have our own mature R & D team and R & D center. We have passed the ISO9001, ISO14001, OHSAH18001, GMP and FDA certification, and have independent import and export rights
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08

BePharma
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BePharma
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Ademetionine

About the Company : Suzhou Pharmaceutical Technology Co.,Ltd Is A Corporation Which Engaged In The R&D And Manufacture Of Chemicals, Pharmaceuticals And Intermediates. We Have Earned Ourselves A Good ...

Suzhou Pharmaceutical Technology Co.,Ltd Is A Corporation Which Engaged In The R&D And Manufacture Of Chemicals, Pharmaceuticals And Intermediates. We Have Earned Ourselves A Good Reputation At Home And Abroad With Advanced Technology, Standardized Management And Well Established Service Systerm. We Have Developed To A Very Famous Group Corporation Enterprise In Chemical Industry Step By Step. Over The Past Years, We Are Engaged In The Exporting Business, Our Products Have Reached Far To The USA, Europe, South Asia, Middle East And So On, Also Our Company Has Established Long Term And Stable Business Relationships With Our Customers.
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09

BePharma
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BePharma
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Ademetionine

About the Company : Viyash, true to its name, literally represents honesty and leadership in every sense. We are an integrated pharmaceutical company with a strong portfolio of niche formulations, ...

Viyash, true to its name, literally represents honesty and leadership in every sense. We are an integrated pharmaceutical company with a strong portfolio of niche formulations, APIs and advanced intermediates Viyash and its subsidiaries operate 10 API / Intermediate facilities with a combined capacity ~2000 KL and diversified capabilities in every aspect - small / large volume, potent / non-potent, regulated / semi-regulated markets. In addition, we also operate one formulation manufacturing facility in New Jersey, USA with a capacity of ~ 1.2 Bn units.
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API Reference Price

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Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1711391400,"product":"ADEMETIONINE 1,4 BUTANEDISULFONATE BATCH NO. 1E240203 AS PERINV","address":"208,ISCON ELEGANCE,CIRCLE-P,PRAHLAD","city":"AHMEDABAD , GUJARAT","supplier":"SHANDONG JINCHENG BIO PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"LA RENON HEALTHCARE PRIVATE LTD","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"315","totalValueFC":"158854.7","currency":"USD","unitRateINR":"26381.3","date":"26-Mar-2024","totalValueINR":"13190625","totalValueInUsd":"158854.7","indian_port":"Ahmedabad Air","hs_no":"29349990","bill_no":"2737911","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"JIAO WANG FU XIAN ROAD NORTH, DONGYI ROAD WEST, ZICHUAN ECONOMIC DEVELOPMENT ZONE,ZIBO CITY,SHANDONG PRO CHINA","customerAddress":"208,ISCON ELEGANCE,CIRCLE-P,PRAHLAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715625000,"product":"ADEMETIONINE 1,4 BUTANEDISULFONATE BATCH NO. 1E240401 AS PERINV","address":"208,ISCON ELEGANCE,CIRCLE-P,PRAHLAD","city":"AHMEDABAD , GUJARAT","supplier":"SHANDONG JINCHENG BIO PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"LA RENON HEALTHCARE PRIVATE LTD","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"290","totalValueFC":"146732.3","currency":"USD","unitRateINR":"24461.5","date":"14-May-2024","totalValueINR":"12230750","totalValueInUsd":"146732.3","indian_port":"Ahmedabad Air","hs_no":"29349990","bill_no":"3474199","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"JIAO WANG FU XIAN ROAD NORTH, DONGYI ROAD WEST, ZICHUAN ECONOMIC DEVELOPMENT ZONE,ZIBO CITY,SHANDONG PRO CHINA","customerAddress":"208,ISCON ELEGANCE,CIRCLE-P,PRAHLAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724869800,"product":"ADEMETIONINE 1,4-BUTANEDISULFONATE (FORM10\/ IL\/BD-013555RC\/BD-002665 DT 19\/06\/2023)","address":"304,MOHAN PLACE,L.S.C.BLOCK-C","city":"DELHI","supplier":"SHANDONG JINCHENG BIO PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"AKUMS DRUGS AND PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"285","totalValueFC":"144150.4","currency":"USD","unitRateINR":"24182.3","date":"29-Aug-2024","totalValueINR":"12091125","totalValueInUsd":"144150.4","indian_port":"Delhi Air","hs_no":"29349990","bill_no":"5317047","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"JIAO WANG FU XIAN ROAD NORTH DONG YI ROAD WEST ZICHUAN ECONOMIC DEVELOPMENT ZONE ZIBO CITY SHANDONG PROV CHINA","customerAddress":"304,MOHAN PLACE,L.S.C.BLOCK-C"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730831400,"product":"ADEMETIONINE 1,4 BUTANEDISULFONATE BATCH NO. 1E241001 AS PERINV","address":"208,ISCON ELEGANCE,CIRCLE-P,PRAHLAD","city":"AHMEDABAD , GUJARAT","supplier":"SHANDONG JINCHENG BIO PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"LA RENON HEALTHCARE PRIVATE LTD","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"290","totalValueFC":"145965.3","currency":"USD","unitRateINR":"24635.5","date":"06-Nov-2024","totalValueINR":"12317750","totalValueInUsd":"145965.3","indian_port":"Ahmedabad Air","hs_no":"29349990","bill_no":"6524523","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"JIAO WANG FU XIAN ROAD NORTH, DONG YI ROAD WEST, ZICHUAN ECONOMIC DEVE LOPMENT ZONE,ZIBO CITY,SHANDONG PRO CHINA","customerAddress":"208,ISCON ELEGANCE,CIRCLE-P,PRAHLAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732818600,"product":"ADEMETIONINE 1,4-BUTANEDISULFONATE","address":"194 ARVIND CHAMBERS 07 SAI SERVICE","city":"MUMBAI,MAHARASHTRA","supplier":"SHANDONG JINCHENG BIO PHARMACEUTICAL COLTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"RIFA PHARMA","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"400","totalValueFC":"809.1","currency":"USD","unitRateINR":"34140","date":"29-Nov-2024","totalValueINR":"68280","totalValueInUsd":"809.1","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"6956823","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"JIAO WANG FU XIAN ROAD NORTH, DONG YI ROAD WEST, ZICHUAN ECONOMIC DEVE LOPMENT ZONE, ZIBO CITY, SHANDONG P China","customerAddress":"194 ARVIND CHAMBERS 07 SAI SERVICE"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1738693800,"product":"NUCLEIC ACIDS AND THEIR SALTS; WHETHER OR NOT CHEMICALLY DEFINED OTHER HETEROCYCLIC COMPOUNDS,ADEMETIONINE 1,4 S29+C0+NANUCLEIC ACIDS AND THEIR SALTS; WHETHER OR NOT CHEMICALLY DEF","address":"3-4, CORPORATE PARK,","city":"MUMBAI. MAHARASHTRA","supplier":"ABBOTT PRODUCTS OPERATIONS AG","supplierCountry":"SWITZERLAND","foreign_port":"AMSTERDAM, SCHIPHOL","customer":"ABBOTT INDIA LTD","customerCountry":"INDIA","quantity":"1066.73","actualQuantity":"1066.73","unit":"KGS","unitRateFc":"386.6","totalValueFC":"413021","currency":"USD","unitRateINR":"33671.1","date":"05-Feb-2025","totalValueINR":"35917991.4","totalValueInUsd":"413021","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"8192012","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"AMSTERDAM, SCHIPHOL","supplierAddress":"HEGENHEIMERMATTWEG 127CH-4123 ALLSC HWIL 1 SDNF SWITZERLAND","customerAddress":"3-4, CORPORATE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1766946600,"product":"ADEMETIONINE 1,4-BUTANEDISULFONATE ADEMETIONINE 1,4-BUTANEDISULFONATE","address":"304,MOHAN PLACE,L.S.C.BLOCK-C","city":"DELHI","supplier":"SHANDONG JINCHENG BIO PHARMACEUTICAL COLTD","supplierCountry":"CHINA","foreign_port":"CHENGDU","customer":"AKUMS DRUGS AND PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"260","totalValueFC":"395412.7","currency":"USD","unitRateINR":"23725","date":"29-Dec-2025","totalValueINR":"35587500","totalValueInUsd":"395412.7","indian_port":"Delhi Air","hs_no":"29349990","bill_no":"4","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHENGDU","supplierAddress":"JIAO WANG FU XIAN ROAD NORTH DONG Y I ROAD WEST ZICHUAN ECONOMIC DEVELO PMENT ZONE ZIBO CITY SHANDONG PROVI CHINA","customerAddress":"304,MOHAN PLACE,L.S.C.BLOCK-C"}]
27-Jan-2022
29-Dec-2025
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

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API Imports and Exports

Importing Country Total Quantity
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Drugs in Development

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Details:

S-Adenosylmethionine is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Jarrow Formulas

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 14, 2024

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01

Cedars-Sinai

U.S.A
arrow
BePharma
Not Confirmed

Cedars-Sinai

U.S.A
arrow
BePharma
Not Confirmed

Lead Product(s) : Ademetionine,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Jarrow Formulas

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : S-Adenosylmethionine is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

February 14, 2024

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  • Development Update

Details:

Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Depressive Disorder, Major.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Psychiatry/Psychology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Vitamins/Minerals/Inorganic Salts

Sponsor: Algorithme Pharma Inc.

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable November 10, 2020

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02

MSI Methylation Sciences Inc

Country
arrow
BePharma
Not Confirmed

MSI Methylation Sciences Inc

Country
arrow
BePharma
Not Confirmed

Details : Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Depressive Disorder, Major.

Product Name : Undisclosed

Product Type : Vitamins/Minerals/Inorganic Salts

Upfront Cash : Inapplicable

November 10, 2020

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  • Development Update

Details:

SAMEUp (S-Adenosyl Methionine) is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in clinical studies for the treatment of Depression.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Psychiatry/Psychology Brand Name: SAMEUp

Study Phase: UndisclosedProduct Type: Vitamins/Minerals/Inorganic Salts

Sponsor: Hippocrates Research

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 30, 2019

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03

Nutrilinea

Country
arrow
BePharma
Not Confirmed

Nutrilinea

Country
arrow
BePharma
Not Confirmed

Details : SAMEUp (S-Adenosyl Methionine) is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in clinical studies for the treatment of Depression.

Product Name : SAMEUp

Product Type : Vitamins/Minerals/Inorganic Salts

Upfront Cash : Inapplicable

April 30, 2019

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  • Development Update

Details:

S-Adenosyl Methionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in clinical studies for the treatment of Carcinoma, Hepatocellular.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Vitamins/Minerals/Inorganic Salts

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable June 07, 2017

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04

Beijing Insight Science & Technology

Country
arrow
BePharma
Not Confirmed

Beijing Insight Science & Technology

Country
arrow
BePharma
Not Confirmed

Details : S-Adenosyl Methionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in clinical studies for the treatment of Carcinoma, Hepatocellular.

Product Name : Undisclosed

Product Type : Vitamins/Minerals/Inorganic Salts

Upfront Cash : Inapplicable

June 07, 2017

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Details:

Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Cholestasis, Intrahepatic, Liver Diseases, Alcoholic.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Vitamins/Minerals/Inorganic Salts

Sponsor: Ascent | Datamap | ClinIntel | Catalent Pharma Solutions

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable July 25, 2014

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05

BePharma
Not Confirmed
BePharma
Not Confirmed

Lead Product(s) : Ademetionine,Inapplicable

Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

Highest Development Status : Phase III

Partner/Sponsor/Collaborator : Ascent | Datamap | ClinIntel | Catalent Pharma Solutions

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Cholestasis, Intrahepatic, Liver Diseases, Alcoholic.

Product Name : Undisclosed

Product Type : Vitamins/Minerals/Inorganic Salts

Upfront Cash : Inapplicable

July 25, 2014

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Details:

Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hepatitis, Alcoholic.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Vitamins/Minerals/Inorganic Salts

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 31, 2013

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06

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hepatitis, Alcoholic.

Product Name : Undisclosed

Product Type : Vitamins/Minerals/Inorganic Salts

Upfront Cash : Inapplicable

December 31, 2013

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Details:

Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hepatitis B.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Infections and Infectious Diseases Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Vitamins/Minerals/Inorganic Salts

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 02, 2013

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07

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Ademethionine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hepatitis B.

Product Name : Undisclosed

Product Type : Vitamins/Minerals/Inorganic Salts

Upfront Cash : Inapplicable

December 02, 2013

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Details:

S-Adenosyl-L-Methionine is a Plant Extract/Herbal drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.


Lead Product(s): Ademetionine,Inapplicable

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Plant Extract/Herbal

Sponsor: PPD

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 21, 2012

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08

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : S-Adenosyl-L-Methionine is a Plant Extract/Herbal drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.

Product Name : Undisclosed

Product Type : Plant Extract/Herbal

Upfront Cash : Inapplicable

December 21, 2012

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FDF Dossiers

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01

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Samyr 

Dosage Form :

Dosage Strength : 20 Cpr Gastrores 400 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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02

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Samyr 

Dosage Form :

Dosage Strength : 20 Cpr Gastrores 200 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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03

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Transmetil

Dosage Form :

Dosage Strength : 10 Cpr Gastrores 500 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Donamet

Dosage Form :

Dosage Strength : 10 Cpr Gastrores 500 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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05

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Samyr 

Dosage Form :

Dosage Strength : 5 Ampoule 400 Mg + 5 Vials Solv 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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06

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Transmetil

Dosage Form :

Dosage Strength : 5 Vials 500 Mg + 5 Vials Solv 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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07

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Donamet

Dosage Form :

Dosage Strength : 5 Vials 500 Mg + 5 Vials Solv 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

08

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Samyr 200

Dosage Form :

Dosage Strength : 5 Bottles 200 Mg + 5 Vials Solv 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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09

Farmak JSC

Ukraine
BePharma
Not Confirmed
arrow

Farmak JSC

Ukraine
arrow
BePharma
Not Confirmed

SCHEMBL25176

Brand Name : Hep-Art

Dosage Form : Lyophilizate

Dosage Strength : 400MG

Packaging : Vial & 5ML Solvent

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Ukraine

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10

Farmak JSC

Ukraine
BePharma
Not Confirmed
arrow

Farmak JSC

Ukraine
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Product Under Development

Dosage Form : Tablet

Dosage Strength : 400MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Ukraine

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Europe

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01

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Samyr 

Dosage Form :

Dosage Strength : 20 Cpr Gastrores 400 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

02

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Samyr 

Dosage Form :

Dosage Strength : 20 Cpr Gastrores 200 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

03

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Donamet

Dosage Form :

Dosage Strength : 10 Cpr Gastrores 500 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

04

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Transmetil

Dosage Form :

Dosage Strength : 5 Vials 500 Mg + 5 Vials Solv 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

05

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Donamet

Dosage Form :

Dosage Strength : 5 Vials 500 Mg + 5 Vials Solv 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

06

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Samyr 200

Dosage Form :

Dosage Strength : 5 Bottles 200 Mg + 5 Vials Solv 5 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

07

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

Ademetionine

Brand Name : Heptral®

Dosage Form : Solution For Injection

Dosage Strength : 500mg

Packaging :

Approval Date : 12-03-2021

Application Number :

Regulatory Info :

Registration Country : Moldova

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08

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

Ademetionine

Brand Name : Heptral®

Dosage Form : Gastro-Resistant Tablet

Dosage Strength : 400mg

Packaging :

Approval Date : 12-05-2021

Application Number :

Regulatory Info :

Registration Country : Moldova

blank

09

Farmak JSC

Ukraine
BePharma
Not Confirmed
arrow

Farmak JSC

Ukraine
arrow
BePharma
Not Confirmed

S-Adenosylmethionine

Brand Name : Product Under Development

Dosage Form : Tablet

Dosage Strength : 400MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Ukraine

blank

10

BePharma
Not Confirmed
arrow
arrow
BePharma
Not Confirmed

Ademetionine

Brand Name : Breathe

Dosage Form : Solution For Injection

Dosage Strength : 400mg

Packaging :

Approval Date : 10-09-2020

Application Number :

Regulatory Info :

Registration Country : Moldova

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ABOUT THIS PAGE

Looking for 485-80-3 / Ademetionine API manufacturers, exporters & distributors?

Ademetionine manufacturers, exporters & distributors 1

44

PharmaCompass offers a list of Ademetionine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ademetionine manufacturer or Ademetionine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ademetionine manufacturer or Ademetionine supplier.

PharmaCompass also assists you with knowing the Ademetionine API Price utilized in the formulation of products. Ademetionine API Price is not always fixed or binding as the Ademetionine Price is obtained through a variety of data sources. The Ademetionine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ademetionine

Synonyms

S-adenosylmethionine, Adomet, 485-80-3, Donamet, S-adenosyl methionine, Adenosylmethionine

Cas Number

485-80-3

About Ademetionine

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)

Knoll Brand of Brand of Ademetionine Tosilate Disulfate Manufacturers

A Knoll Brand of Brand of Ademetionine Tosilate Disulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Knoll Brand of Brand of Ademetionine Tosilate Disulfate, including repackagers and relabelers. The FDA regulates Knoll Brand of Brand of Ademetionine Tosilate Disulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Knoll Brand of Brand of Ademetionine Tosilate Disulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Knoll Brand of Brand of Ademetionine Tosilate Disulfate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Knoll Brand of Brand of Ademetionine Tosilate Disulfate Suppliers

A Knoll Brand of Brand of Ademetionine Tosilate Disulfate supplier is an individual or a company that provides Knoll Brand of Brand of Ademetionine Tosilate Disulfate active pharmaceutical ingredient (API) or Knoll Brand of Brand of Ademetionine Tosilate Disulfate finished formulations upon request. The Knoll Brand of Brand of Ademetionine Tosilate Disulfate suppliers may include Knoll Brand of Brand of Ademetionine Tosilate Disulfate API manufacturers, exporters, distributors and traders.

click here to find a list of Knoll Brand of Brand of Ademetionine Tosilate Disulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Knoll Brand of Brand of Ademetionine Tosilate Disulfate USDMF

A Knoll Brand of Brand of Ademetionine Tosilate Disulfate DMF (Drug Master File) is a document detailing the whole manufacturing process of Knoll Brand of Brand of Ademetionine Tosilate Disulfate active pharmaceutical ingredient (API) in detail. Different forms of Knoll Brand of Brand of Ademetionine Tosilate Disulfate DMFs exist exist since differing nations have different regulations, such as Knoll Brand of Brand of Ademetionine Tosilate Disulfate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Knoll Brand of Brand of Ademetionine Tosilate Disulfate DMF submitted to regulatory agencies in the US is known as a USDMF. Knoll Brand of Brand of Ademetionine Tosilate Disulfate USDMF includes data on Knoll Brand of Brand of Ademetionine Tosilate Disulfate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Knoll Brand of Brand of Ademetionine Tosilate Disulfate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Knoll Brand of Brand of Ademetionine Tosilate Disulfate suppliers with USDMF on PharmaCompass.

Knoll Brand of Brand of Ademetionine Tosilate Disulfate GMP

Knoll Brand of Brand of Ademetionine Tosilate Disulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Knoll Brand of Brand of Ademetionine Tosilate Disulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Knoll Brand of Brand of Ademetionine Tosilate Disulfate GMP manufacturer or Knoll Brand of Brand of Ademetionine Tosilate Disulfate GMP API supplier for your needs.

Knoll Brand of Brand of Ademetionine Tosilate Disulfate CoA

A Knoll Brand of Brand of Ademetionine Tosilate Disulfate CoA (Certificate of Analysis) is a formal document that attests to Knoll Brand of Brand of Ademetionine Tosilate Disulfate's compliance with Knoll Brand of Brand of Ademetionine Tosilate Disulfate specifications and serves as a tool for batch-level quality control.

Knoll Brand of Brand of Ademetionine Tosilate Disulfate CoA mostly includes findings from lab analyses of a specific batch. For each Knoll Brand of Brand of Ademetionine Tosilate Disulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Knoll Brand of Brand of Ademetionine Tosilate Disulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Knoll Brand of Brand of Ademetionine Tosilate Disulfate EP), Knoll Brand of Brand of Ademetionine Tosilate Disulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Knoll Brand of Brand of Ademetionine Tosilate Disulfate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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