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  • Development Update

Details:

GSK, has stopped its Phase II trial of anti-LAG3 cell depleting monoclonal antibody, GSK2831781 (derived from Immutep’s IMP731 antibody), in patients with active ulcerative colitis. The trial was stopped based on the assessment of clinical data of planned interim analysis.


Lead Product(s): IMP731

Therapeutic Area: Gastroenterology Product Name: GSK2831781

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Immutep

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 22, 2021

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Details:

GSK, has discontinued its Phase II clinical trial evaluating an anti-LAG3 cell depleting monoclonal antibody, GSK2831781 (IMP731), in patients with active ulcerative colitis. The collaboration remains in place and GSK2831781 continues to be under an exclusive license with GSK.


Lead Product(s): IMP731

Therapeutic Area: Gastroenterology Product Name: GSK2831781

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: GSK

Deal Size: $100.0 million Upfront Cash: Undisclosed

Deal Type: Licensing Agreement January 22, 2021

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