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Chemistry

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Also known as: Ethidium chloride, 602-52-8, Novidium chloride, 3,8-diamino-5-ethyl-6-phenylphenanthridinium chloride, Nsc-84423, 7xpk80d0xv
Molecular Formula
C21H20ClN3
Molecular Weight
349.9  g/mol
InChI Key
BITVSRNAFFZUFW-UHFFFAOYSA-N
FDA UNII
7XPK80D0XV

Homidium Chloride
Homidium Chloride is the chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor. (NCI04)
1 2D Structure

Homidium Chloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine chloride
2.1.2 InChI
InChI=1S/C21H19N3.ClH/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14;/h3-13,23H,2,22H2,1H3;1H
2.1.3 InChI Key
BITVSRNAFFZUFW-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
7XPK80D0XV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3,8-diamino-5-ethyl-6-phenylphenanthridinium Chloride

2.3.2 Depositor-Supplied Synonyms

1. Ethidium Chloride

2. 602-52-8

3. Novidium Chloride

4. 3,8-diamino-5-ethyl-6-phenylphenanthridinium Chloride

5. Nsc-84423

6. 7xpk80d0xv

7. 2,7-diamino-9-phenyl-10-ethylphenanthridinium Chloride

8. Nsc-522843

9. Nsc84423

10. Nsc522843

11. Refchem:923037

12. 210-018-2

13. Babidium Chloride

14. 5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine;chloride

15. 3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium Chloride

16. Wln: T B666 Hkj Ez H2 Ir& Lz &q &g

17. Einecs 210-018-2

18. Phenanthridinium,8-diamino-5-ethyl-6-phenyl Chloride

19. Unii-7xpk80d0xv

20. Nsc 522843

21. Phenanthridinium,8-diamino-5-ethyl-6-phenyl-, Chloride

22. Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl Chloride

23. Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-, Chloride

24. Ethidium Chloride (et)

25. Chembl27580

26. Schembl612343

27. Orb1740456

28. Dtxsid5037078

29. Ns00080368

30. Q27268986

31. 2,7-diamino-10-ethyl-9-phenylphenanthridinium Chloride

32. 3,8-diamino-5-ethyl-6-phenylphenanthridin-5-iumchloride

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 349.9 g/mol
Molecular Formula C21H20ClN3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area55.9
Heavy Atom Count25
Formal Charge0
Complexity419
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Trypanocidal Agents

Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.


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Homidium Chloride manufacturers, exporters & distributors 1

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Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Homidium Chloride manufacturer or Homidium Chloride supplier.

API | Excipient name

Homidium Chloride

Synonyms

Ethidium chloride, 602-52-8, Novidium chloride, 3,8-diamino-5-ethyl-6-phenylphenanthridinium chloride, Nsc-84423, 7xpk80d0xv

Cas Number

602-52-8

Unique Ingredient Identifier (UNII)

7XPK80D0XV

About Homidium Chloride

Homidium Chloride is the chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor. (NCI04)

Homidium Chloride Manufacturers

A Homidium Chloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Homidium Chloride, including repackagers and relabelers. The FDA regulates Homidium Chloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Homidium Chloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Homidium Chloride Suppliers

A Homidium Chloride supplier is an individual or a company that provides Homidium Chloride active pharmaceutical ingredient (API) or Homidium Chloride finished formulations upon request. The Homidium Chloride suppliers may include Homidium Chloride API manufacturers, exporters, distributors and traders.

Homidium Chloride GMP

Homidium Chloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Homidium Chloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Homidium Chloride GMP manufacturer or Homidium Chloride GMP API supplier for your needs.

Homidium Chloride CoA

A Homidium Chloride CoA (Certificate of Analysis) is a formal document that attests to Homidium Chloride's compliance with Homidium Chloride specifications and serves as a tool for batch-level quality control.

Homidium Chloride CoA mostly includes findings from lab analyses of a specific batch. For each Homidium Chloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Homidium Chloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Homidium Chloride EP), Homidium Chloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Homidium Chloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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