DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Virtual Booth

Contact Supplier

Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

ACCESS ALL DATA
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

30 Drugs in Development

30 Drugs in Development

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

1PROSPECTS

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

API/FDF Prices: Book a Demo

API REF. PRICE (USD/KG)

$ 0

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Regulatory FDF Prices

MARKET PLACE

API

FDF

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Fluzoparib, 1358715-18-0, Fuzuopali, Shr-3162, Shr3162, Twf0ml1ck8

Molecular Formula

C₂₂H₁₆F₄N₆O₂

Molecular Weight

472.4 g/mol

InChI Key

XJGXCBHXFWBOTN-UHFFFAOYSA-N

FDA UNII

TWF0ML1CK8

FLUZOPARIB is a small molecule drug with a maximum clinical trial phase of III (across all indications) and has 21 investigational indications.

1 2D Structure

Fuzuloparib

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[[4-fluoro-3-[2-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[1,5-a]pyrazine-7-carbonyl]phenyl]methyl]-2H-phthalazin-1-one

2.1.2 InChI

InChI=1S/C22H16F4N6O2/c23-16-6-5-12(10-17-13-3-1-2-4-14(13)19(33)29-28-17)9-15(16)20(34)31-7-8-32-18(11-31)27-21(30-32)22(24,25)26/h1-6,9H,7-8,10-11H2,(H,29,33)

2.1.3 InChI Key

XJGXCBHXFWBOTN-UHFFFAOYSA-N

2.2 Other Identifiers

2.2.1 UNII

TWF0ML1CK8

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Fluzoparib

2. 4-((4-fluoro-3-(2-(trifluoromethyl)-6,8-dihydro-5h-(1,2,4)triazolo(1,5-a)pyrazine-7-carbonyl)phenyl)methyl)-2h-phthalazin-1-one

3. Shr3162

2.3.2 Depositor-Supplied Synonyms

1. Fluzoparib

2. 1358715-18-0

3. Fuzuopali

4. Shr-3162

5. Shr3162

6. Twf0ml1ck8

7. 4-[[4-fluoro-3-[2-(trifluoromethyl)-6,8-dihydro-5h-[1,2,4]triazolo[1,5-a]pyrazine-7-carbonyl]phenyl]methyl]-2h-phthalazin-1-one

8. Hs10160

9. Hs-10160

10. 1(2h)-phthalazinone, 4-((3-((5,6-dihydro-2-(trifluoromethyl)(1,2,4)triazolo(1,5-a)pyrazin-7(8h)-yl)carbonyl)-4-fluorophenyl)methyl)-

11. 4-((3-((5,6-dihydro-2-(trifluoromethyl)(1,2,4)triazolo(1,5-a)pyrazin-7(8h)-yl)carbonyl)-4-fluorophenyl)methyl)-1(2h)-phthalazinone

12. Airuiyi

13. 4-((4-fluoro-3-(2-(trifluoromethyl)-6,8-dihydro-5h-(1,2,4)triazolo(1,5-a)pyrazine-7-carbonyl)phenyl)methyl)-2h-phthalazin-1-one

14. Refchem:141090

15. 4-((4-fluoro-3-(2-(trifluoromethyl)-5h,6h,7h,8h-(1,2,4)triazolo(1,5-a)pyrazine-7-carbonyl)phenyl)methyl)-1,2-dihydrophthalazin-1-one

16. Unii-twf0ml1ck8

17. Fluzoparib (shr-3162)

18. 4-(4-fluoro-3-(2-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine-7-carbonyl)benzyl)phthalazin-1(2h)-one

19. Fluzoparib?

20. 25i

21. Fuzuloparib [inn]

22. Fluzoparib [who-dd]

23. Orb1298619

24. Chembl3930624

25. Schembl10025553

26. Schembl29361923

27. Schembl30641389

28. Gtpl13763

29. C22h16f4n6o2

30. Dtxsid801374052

31. Glxc-23874

32. Hms5086g20

33. Ex-a8180

34. Shr3162; Fuzuopali; Fuzuloparibum

35. S9712

36. Ms-28738

37. Hy-114778

38. Cs-0064303

39. G17612

2.4 Create Date

2012-03-05

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₁₆F₄N₆O₂
Molecular Weight	472.4 g/mol
XLogP3	2.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Exact Mass	Da
Monoisotopic Mass	Da
Topological Polar Surface Area	92.5
Heavy Atom Count	34
Formal Charge	0
Complexity	839
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Treatment of prostate cancer

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Poly(ADP-ribose) Polymerase Inhibitors

Chemicals and drugs that inhibit the action of POLY(ADP-RIBOSE)POLYMERASES.

Drugs in Development

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Privacy policy
Terms and conditions
Disclaimers
Product listings are provided for informational purposes only. We do not supply or sell any products. Any products that may be covered by patent(s) are supplied solely for uses permitted under Section 107A of the Indian Patents Act and not for commercial sale.

Find Fuzuloparib manufacturers, exporters & distributors on PharmaCompass

Fuzuloparib

ACCESS ALL DATA

CHEMISTRY

Discover Molecule Insights

DEVELOPMENTS

30 Drugs in Development

ACTIVE PHARMA INGREDIENTS

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

FINISHED DOSAGE FORMULATIONS

1PROSPECTS

30DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

API REF. PRICE (USD/KG)

$ 0

GLOBAL SALES INFORMATION

MARKET PLACE

DIGITAL CONTENT

What are you looking for?