Find Floctafenine manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 23779-99-9, Novodolan, Idarac, Diralgan, Idalon, 2,3-dihydroxypropyl 2-((8-(trifluoromethyl)quinolin-4-yl)amino)benzoate
Molecular Formula
C20H17F3N2O4
Molecular Weight
406.4  g/mol
InChI Key
APQPGQGAWABJLN-UHFFFAOYSA-N
FDA UNII
O04HVX6A9Q

Floctafenine
Floctafenine is an anti-inflammatory analgesic similar in action to aspirin. Floctafenine inhibits prostaglandin synthesis.
1 2D Structure

Floctafenine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2,3-dihydroxypropyl 2-[[8-(trifluoromethyl)quinolin-4-yl]amino]benzoate
2.1.2 InChI
InChI=1S/C20H17F3N2O4/c21-20(22,23)15-6-3-5-13-17(8-9-24-18(13)15)25-16-7-2-1-4-14(16)19(28)29-11-12(27)10-26/h1-9,12,26-27H,10-11H2,(H,24,25)
2.1.3 InChI Key
APQPGQGAWABJLN-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC=C(C(=C1)C(=O)OCC(CO)O)NC2=C3C=CC=C(C3=NC=C2)C(F)(F)F
2.2 Other Identifiers
2.2.1 UNII
O04HVX6A9Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Duralgin

2. Floctafenin

3. Idalon

4. Idarac

5. Novodolan

6. R 4318

7. Ru 15750

2.3.2 Depositor-Supplied Synonyms

1. 23779-99-9

2. Novodolan

3. Idarac

4. Diralgan

5. Idalon

6. 2,3-dihydroxypropyl 2-((8-(trifluoromethyl)quinolin-4-yl)amino)benzoate

7. Floctafenin

8. Ru 15750

9. R 4318

10. 2,3-dihydroxypropyl 2-[[8-(trifluoromethyl)quinolin-4-yl]amino]benzoate

11. 8-trifluoromethyl-7-deschloroglafenine

12. 2,3-dihydroxypropyl 2-((8-(trifluoromethyl)-quinolin-4-yl)amino)benzoate

13. Ru-15750

14. 2,3-dihydroxypropyl N-(8-(trifluoromethyl)-4-quinolyl)anthranilate

15. O04hvx6a9q

16. Benzoic Acid, 2-((8-(trifluoromethyl)-4-quinolinyl)amino)-, 2,3-dihydroxypropyl Ester

17. R-4138

18. R-4318

19. 2-(8'-trifluoromethyl-4'-quinolylamino)benzoic Acid 2,3-dihydroxy Propyl Ester

20. 4-(o-(2',3'-dihydroxypropyloxycarbonyl)phenyl)-amino-8-trifluoromethylquinoline

21. Benzoic Acid, 2-(8'-trifluoromethyl-4'-quinolylamino)-, 2,3-dihydroxypropyl Ester

22. Benzoic Acid, 2-[[8-(trifluoromethyl)-4-quinolinyl]amino]-, 2,3-dihydroxypropyl Ester

23. Floctafenina

24. Floctafeninum

25. Duralgin

26. Floctafeninum [inn-latin]

27. Floctafenina [inn-spanish]

28. Einecs 245-881-4

29. Unii-o04hvx6a9q

30. Brn 0457808

31. Floctafenine [usan:inn:ban:jan]

32. Idarac (tn)

33. Floctafenine [mi]

34. Floctafenine [inn]

35. Floctafenine [jan]

36. Floctafenine [usan]

37. Dsstox_cid_31484

38. Dsstox_rid_97369

39. Dsstox_gsid_57695

40. Schembl26841

41. Floctafenine [mart.]

42. Floctafenine [who-dd]

43. Floctafenine (jan/usan/inn)

44. Chembl2105075

45. Dtxsid8057695

46. Chebi:31612

47. Hy-a0259

48. Tox21_113688

49. Akos015998661

50. Db08976

51. Sb73211

52. Ncgc00249912-01

53. Cas-23779-99-9

54. Cs-0017604

55. Ft-0668555

56. D01267

57. A878143

58. Q5459971

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 406.4 g/mol
Molecular Formula C20H17F3N2O4
XLogP33.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Exact Mass406.11404151 g/mol
Monoisotopic Mass406.11404151 g/mol
Topological Polar Surface Area91.7 Ų
Heavy Atom Count29
Formal Charge0
Complexity548
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


4.2 ATC Code

N - Nervous system

N02 - Analgesics

N02B - Other analgesics and antipyretics

N02BG - Other analgesics and antipyretics

N02BG04 - Floctafenine


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Looking for 23779-99-9 / Floctafenine API manufacturers, exporters & distributors?

Floctafenine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Floctafenine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Floctafenine manufacturer or Floctafenine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Floctafenine manufacturer or Floctafenine supplier.

PharmaCompass also assists you with knowing the Floctafenine API Price utilized in the formulation of products. Floctafenine API Price is not always fixed or binding as the Floctafenine Price is obtained through a variety of data sources. The Floctafenine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Floctafenine

Synonyms

23779-99-9, Novodolan, Idarac, Diralgan, Idalon, 2,3-dihydroxypropyl 2-((8-(trifluoromethyl)quinolin-4-yl)amino)benzoate

Cas Number

23779-99-9

Unique Ingredient Identifier (UNII)

O04HVX6A9Q

About Floctafenine

Floctafenine is an anti-inflammatory analgesic similar in action to aspirin. Floctafenine inhibits prostaglandin synthesis.

Floctafenine Manufacturers

A Floctafenine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Floctafenine, including repackagers and relabelers. The FDA regulates Floctafenine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Floctafenine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Floctafenine Suppliers

A Floctafenine supplier is an individual or a company that provides Floctafenine active pharmaceutical ingredient (API) or Floctafenine finished formulations upon request. The Floctafenine suppliers may include Floctafenine API manufacturers, exporters, distributors and traders.

Floctafenine GMP

Floctafenine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Floctafenine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Floctafenine GMP manufacturer or Floctafenine GMP API supplier for your needs.

Floctafenine CoA

A Floctafenine CoA (Certificate of Analysis) is a formal document that attests to Floctafenine's compliance with Floctafenine specifications and serves as a tool for batch-level quality control.

Floctafenine CoA mostly includes findings from lab analyses of a specific batch. For each Floctafenine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Floctafenine may be tested according to a variety of international standards, such as European Pharmacopoeia (Floctafenine EP), Floctafenine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Floctafenine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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