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Chemistry

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Also known as: 1044040-56-3, Shr1020, Shr-1020, Famitinib, (z), 945380-27-8, Unii-768fw21j3l
Molecular Formula
C23H27FN4O2
Molecular Weight
410.5  g/mol
InChI Key
GKEYKDOLBLYGRB-LGMDPLHJSA-N
FDA UNII
768FW21J3L

Famitinib
FAMITINIB is a small molecule drug with a maximum clinical trial phase of III (across all indications) and has 17 investigational indications.
1 2D Structure

Famitinib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-[2-(diethylamino)ethyl]-2-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-3-methyl-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4-one
2.1.2 InChI
InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-
2.1.3 InChI Key
GKEYKDOLBLYGRB-LGMDPLHJSA-N
2.2 Other Identifiers
2.2.1 UNII
768FW21J3L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5-(2-(diethylamino)ethyl0-2-9(z)-(5-fluoro-2-oxo-1h-indol-3-ylidene)methyl)-3-methyl-6,7-dihydro-1h-pyrrolo(3,2-c)pyridin-4(5h)-one

2. Shr1020

2.3.2 Depositor-Supplied Synonyms

1. 1044040-56-3

2. Shr1020

3. Shr-1020

4. Famitinib, (z)

5. 945380-27-8

6. Unii-768fw21j3l

7. 768fw21j3l

8. Famitinib [inn]

9. Famitinib [who-dd]

10. Chembl1278146

11. Shr 1020

12. 5-[2-(diethylamino)ethyl]-2-[(z)-(5-fluoro-2-oxo-1h-indol-3-ylidene)methyl]-3-methyl-6,7-dihydro-1h-pyrrolo[3,2-c]pyridin-4-one

13. Compound 9 [pmid: 21028894]

14. Compound 9 (pmid: 21028894)

15. (z)-5-(2-(diethylamino)ethyl)-2-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-3-methyl-6,7-dihydro-1h-pyrrolo(3,2-c)pyridin-4(5h)-one

16. 4h-pyrrolo(3,2-c)pyridin-4-one, 5-(2-(diethylamino)ethyl)-2-((5-fluoro-1,2-dihydro-2-oxo-3h-indol-3-ylidene)methyl)-1,5,6,7-tetrahydro-3-methyl-

17. 4h-pyrrolo(3,2-c)pyridin-4-one, 5-(2-(diethylamino)ethyl)-2-((z)-(5-fluoro-1,2-dihydro-2-oxo-3h-indol-3-ylidene)methyl)-1,5,6,7-tetrahydro-3-methyl-

18. 5-(2-(diethylamino)ethyl)-2-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-3-methyl-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one

19. 5-(2-(diethylamino)ethyl0-2-9(z)-(5-fluoro-2-oxo-1h-indol-3-ylidene)methyl)-3-methyl-6,7-dihydro-1h-pyrrolo(3,2-c)pyridin-4(5h)-one

20. 5-(2-diethylaminoethyl)-2-[(z)-(5-fluoro-2-oxo-1h-indol-3-ylidene)methyl]-3-methyl-6,7-dihydro-1h-pyrrolo[4,5-c]pyridin-4-one

21. (3z)-3-((5-(2-(diethylamino)ethyl)-3-methyl-4-oxo-1h,4h,5h,6h,7h-pyrrolo(3,2-c)pyridin-2-yl)methylidene)-5-fluoro-2,3-dihydro-1h-indol-2-one

22. (3z)-3-({5-[2-(diethylamino)ethyl]-3-methyl-4-oxo-1h,4h,5h,6h,7h-pyrrolo[3,2-c]pyridin-2-yl}methylidene)-5-fluoro-2,3-dihydro-1h-indol-2-one

23. 5-(2-diethylaminoethyl)-2-((z)-(5-fluoro-2-oxo-1h-indol-3-ylidene)methyl)-3-methyl-6,7-dihydro-1h-pyrrolo(4,5-c)pyridin-4-one

24. Famitinib (standard)

25. Starbld0044024

26. Famitinib (shr1020)

27. Schembl137251

28. Gtpl7886

29. Ex-a6762

30. Bdbm50331023

31. Db11741

32. Hy-108713r

33. Da-63367

34. Ms-27081

35. Ns00072868

36. G14485

37. Q27077275

38. (z)-2-(5-fluoro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-5-(2-diethylaminoethyl)-3-methyl-1,5,6,7-tetrahydropyrrolo-[3,2-c]pyridin-4-one

39. (z)-5-(2-(diethylamino)ethyl)-2-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-3-methyl-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one

2.4 Create Date
2007-08-13
3 Chemical and Physical Properties
Molecular Weight 410.5 g/mol
Molecular Formula C23H27FN4O2
XLogP32.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area68.4
Heavy Atom Count30
Formal Charge0
Complexity695
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1044040-56-3 / Famitinib API manufacturers, exporters & distributors?

Famitinib manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Famitinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Famitinib manufacturer or Famitinib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Famitinib manufacturer or Famitinib supplier.

PharmaCompass also assists you with knowing the Famitinib API Price utilized in the formulation of products. Famitinib API Price is not always fixed or binding as the Famitinib Price is obtained through a variety of data sources. The Famitinib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Famitinib

Synonyms

1044040-56-3, Shr1020, Shr-1020, Famitinib, (z), 945380-27-8, Unii-768fw21j3l

Cas Number

1044040-56-3

Unique Ingredient Identifier (UNII)

768FW21J3L

About Famitinib

FAMITINIB is a small molecule drug with a maximum clinical trial phase of III (across all indications) and has 17 investigational indications.

Famitinib Manufacturers

A Famitinib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Famitinib, including repackagers and relabelers. The FDA regulates Famitinib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Famitinib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Famitinib Suppliers

A Famitinib supplier is an individual or a company that provides Famitinib active pharmaceutical ingredient (API) or Famitinib finished formulations upon request. The Famitinib suppliers may include Famitinib API manufacturers, exporters, distributors and traders.

Famitinib GMP

Famitinib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Famitinib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Famitinib GMP manufacturer or Famitinib GMP API supplier for your needs.

Famitinib CoA

A Famitinib CoA (Certificate of Analysis) is a formal document that attests to Famitinib's compliance with Famitinib specifications and serves as a tool for batch-level quality control.

Famitinib CoA mostly includes findings from lab analyses of a specific batch. For each Famitinib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Famitinib may be tested according to a variety of international standards, such as European Pharmacopoeia (Famitinib EP), Famitinib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Famitinib USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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