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1. Bicifadine Hydrochloride
1. 71195-57-8
2. 1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane
3. 1-(p-tolyl)-3-azabicyclo[3.1.0]hexane
4. Cl-220075
5. 5-(p-tolyl)-3-azabicyclo[3.1.0]hexane
6. Schembl38793
7. 3-azabicyclo[3.1.0]hexane, 1-(4-methylphenyl)-
8. Chembl511099
9. Dtxsid20867995
10. Hms3743c09
11. Mcv-4147
12. Nih-9542
13. Bdbm50417944
14. Akos006271730
15. At33554
16. Db04889
17. Dov-220075
18. Db-014713
19. 1-(p-tolyl)-3-azabicyclo[3.1.0]-hexane
20. Am20041063
21. Cs-0455133
22. Ft-0718156
23. 195b578
24. A837110
25. 3-azabicyclo[3.1.0]hexane,1-(4-methylphenyl)-,hydrochloride(1:1)
| Molecular Weight | 173.25 g/mol |
|---|---|
| Molecular Formula | C12H15N |
| XLogP3 | 2.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 173.120449483 g/mol |
| Monoisotopic Mass | 173.120449483 g/mol |
| Topological Polar Surface Area | 12 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 205 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For the treatment of pain.
Bicifadine is a chemically distinct molecule with a unique profile of pharmacological activity. Its primary pharmacological action is to enhance and prolong the actions of norepinephrine and serotonin by inhibiting the transport proteins that terminate the physiological actions of the two biogenic amines. Bicifadine is not a narcotic and is well-tolerated and, in preclinical studies, has been shown not to act at any opiate receptor. Bicifadine does not exhibit any anti-inflammatory activity and does not inhibit prostaglandin synthetase in vitro.
The primary enzymes responsible for the primary metabolism of bicifadine in humans are MAO-B and CYP2D6.
Preclinical studies and clinical trials indicate that bicifadine's analgesic properties result through the enhancement and prolongation of norepinephrine and serotonin actions, however other actions may be involved.
ABOUT THIS PAGE
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PharmaCompass offers a list of Bicifadine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Bicifadine manufacturer or Bicifadine supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Bicifadine manufacturer or Bicifadine supplier.
PharmaCompass also assists you with knowing the Bicifadine API Price utilized in the formulation of products. Bicifadine API Price is not always fixed or binding as the Bicifadine Price is obtained through a variety of data sources. The Bicifadine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Bicifadine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bicifadine, including repackagers and relabelers. The FDA regulates Bicifadine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bicifadine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Bicifadine supplier is an individual or a company that provides Bicifadine active pharmaceutical ingredient (API) or Bicifadine finished formulations upon request. The Bicifadine suppliers may include Bicifadine API manufacturers, exporters, distributors and traders.
Bicifadine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Bicifadine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bicifadine GMP manufacturer or Bicifadine GMP API supplier for your needs.
A Bicifadine CoA (Certificate of Analysis) is a formal document that attests to Bicifadine's compliance with Bicifadine specifications and serves as a tool for batch-level quality control.
Bicifadine CoA mostly includes findings from lab analyses of a specific batch. For each Bicifadine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Bicifadine may be tested according to a variety of international standards, such as European Pharmacopoeia (Bicifadine EP), Bicifadine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bicifadine USP).
