Find Afimetoran manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 2171019-55-7, Afimetoran [usan], Lxp7mzl0vf, Bms-986256, Unii-lxp7mzl0vf, Afimetoran [inn]
Molecular Formula
C26H32N6O
Molecular Weight
444.6  g/mol
InChI Key
SNFVHLQYHFQOEP-UHFFFAOYSA-N
FDA UNII
LXP7MZL0VF

Afimetoran
AFIMETORAN is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.
1 2D Structure

Afimetoran

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4-[2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-propan-2-yl-1H-indol-5-yl]piperidin-1-yl]acetamide
2.1.2 InChI
InChI=1S/C26H32N6O/c1-15(2)24-20-11-19(18-7-9-31(10-8-18)13-23(27)33)5-6-22(20)30-25(24)21-12-32-26(28-14-29-32)17(4)16(21)3/h5-6,11-12,14-15,18,30H,7-10,13H2,1-4H3,(H2,27,33)
2.1.3 InChI Key
SNFVHLQYHFQOEP-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
LXP7MZL0VF
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2171019-55-7

2. Afimetoran [usan]

3. Lxp7mzl0vf

4. Bms-986256

5. Unii-lxp7mzl0vf

6. Afimetoran [inn]

7. Bms 986256

8. Afimetoran (usan)

9. 2-(4-(2-(7,8-dimethyl(1,2,4)triazolo(1,5-a)pyridin-6-yl)-3-(propan-2-yl)-1h-indol-5-yl)piperidin-1-yl)acetamide

10. 1-piperidineacetamide, 4-(2-(7,8-dimethyl(1,2,4)triazolo(1,5-a)pyridin-6-yl)-3-(1-methylethyl)-1h-indol-5-yl)-

11. Refchem:110007

12. 2-(4-(2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1h-indol-5-yl)piperidin-1-yl)acetamide

13. Who 11516

14. 2-[4-[2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-propan-2-yl-1h-indol-5-yl]piperidin-1-yl]acetamide

15. 1-piperidineacetamide, 4-(2-(7,8-dimethyl(1,2,4)triazolo(1,5-a)pyridin-6-yl)-3- (1-methylethyl)-1h-indol-5-yl)-

16. Afimetoran [who-dd]

17. Orb1303504

18. Afimetoran (bms-986256)

19. Chembl4650329

20. Schembl19761011

21. C26h32n6o

22. Bdbm273241

23. Ex-a6745

24. Us10071079, Example 15

25. Mfcd34578322

26. Akos040757385

27. Da-70624

28. Ms-28017

29. Hy-139567

30. Cs-0213544

31. D11908

32. G18517

33. 2-(4-(2-(7,8-dimethyl(1,2,4)triazolo(1,5-a)pyridin-6-yl)-3-(propan-2-yl)-1h-indol- 5-yl)piperidin-1-yl)acetamide

34. 2-(4-(2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1h-indol-5-yl) Piperidin-1-yl)acetamide

35. 2-[4-[2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1h-indol-5-yl]-1-piperidyl]acetamide

2.4 Create Date
2018-01-29
3 Chemical and Physical Properties
Molecular Weight 444.6 g/mol
Molecular Formula C26H32N6O
XLogP33.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area92.3
Heavy Atom Count33
Formal Charge0
Complexity694
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Mechanism of Action

Afimetoran acts as an antagonist of TLR 7/8.


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Looking for 2171019-55-7 / Afimetoran API manufacturers, exporters & distributors?

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PharmaCompass offers a list of Afimetoran API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Afimetoran manufacturer or Afimetoran supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Afimetoran manufacturer or Afimetoran supplier.

API | Excipient name

Afimetoran

Synonyms

2171019-55-7, Afimetoran [usan], Lxp7mzl0vf, Bms-986256, Unii-lxp7mzl0vf, Afimetoran [inn]

Cas Number

2171019-55-7

Unique Ingredient Identifier (UNII)

LXP7MZL0VF

About Afimetoran

AFIMETORAN is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.

Afimetoran Manufacturers

A Afimetoran manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Afimetoran, including repackagers and relabelers. The FDA regulates Afimetoran manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Afimetoran API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Afimetoran Suppliers

A Afimetoran supplier is an individual or a company that provides Afimetoran active pharmaceutical ingredient (API) or Afimetoran finished formulations upon request. The Afimetoran suppliers may include Afimetoran API manufacturers, exporters, distributors and traders.

Afimetoran GMP

Afimetoran Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Afimetoran GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Afimetoran GMP manufacturer or Afimetoran GMP API supplier for your needs.

Afimetoran CoA

A Afimetoran CoA (Certificate of Analysis) is a formal document that attests to Afimetoran's compliance with Afimetoran specifications and serves as a tool for batch-level quality control.

Afimetoran CoA mostly includes findings from lab analyses of a specific batch. For each Afimetoran CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Afimetoran may be tested according to a variety of international standards, such as European Pharmacopoeia (Afimetoran EP), Afimetoran JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Afimetoran USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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