Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Zenas BioPharma Completes Phase 3 Trial Enrollment for Obexelimab
Details : ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19. It is being investigated for Immunoglobulin G4-Related Disease.
Product Name : ZB012
Product Type : Antibody
Upfront Cash : Inapplicable
December 11, 2024
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Morgan Stanley
Deal Size : $225.0 million
Deal Type : Public Offering
Zenas BioPharma Announces Pricing of Upsized Initial Public Offering
Details : The net proceeds to advance the clinical development of its lead asset ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19.
Product Name : ZB012
Product Type : Antibody
Upfront Cash : Undisclosed
December 09, 2024
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Morgan Stanley
Deal Size : $225.0 million
Deal Type : Public Offering
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Morgan Stanley
Deal Size : $258.7 million
Deal Type : Public Offering
Zenas BioPharma Closes Full Exercise Of Underwriters’ Option in IPO
Details : The net proceeds to advance the clinical development of its lead asset ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19.
Product Name : ZB012
Product Type : Antibody
Upfront Cash : Undisclosed
September 19, 2024
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Morgan Stanley
Deal Size : $258.7 million
Deal Type : Public Offering
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : SR One Capital Management
Deal Size : $200.0 million
Deal Type : Series C Financing
Zenas BioPharma Upsizes $200 Million Series C Financing for Immunology Programs
Details : The company plans to advance the clinical development of ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits CD19-expressing B-cell lineages.
Product Name : ZB012
Product Type : Antibody
Upfront Cash : Undisclosed
July 05, 2024
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : SR One Capital Management
Deal Size : $200.0 million
Deal Type : Series C Financing
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ZB-O12 (obexelimab) is an investigational Phase 3-stage, novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19 and generates an encouraging treatment effect in patients with multiple autoimmune diseases...
Product Name : ZB012
Product Type : Antibody
Upfront Cash : Inapplicable
November 01, 2023
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Bristol Myers Squibb
Deal Size : Undisclosed
Deal Type : Collaboration
Zenas BioPharma Announces Strategic License and Collaboration Agreement with Bristol Myers Squibb
Details : The collaboration aims to develop and commercialize ZB-O12 (obexelimab), an investigational bifunctional, non-cytolytic, humanized monoclonal antibody that binds CD19 and FcγRIIb, for autoimmune diseases in Japan, South Korea, Taiwan, Singapore, Hong Ko...
Product Name : ZB012
Product Type : Antibody
Upfront Cash : $50.0 million
May 09, 2023
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Bristol Myers Squibb
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Veligrotug
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Viridian Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ZB001 (Viridian VRDN-001) is a differentiated humanized monoclonal antibody targeting insulin-like growth factor 1 receptor (IGF-1R) for the treatment of TED.
Product Name : VRDN-001
Product Type : Antibody
Upfront Cash : Inapplicable
December 05, 2022
Lead Product(s) : Veligrotug
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Viridian Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Enavate Sciences
Deal Size : $118.0 million
Deal Type : Series B Financing
Details : ZB-O12 (obexelimab) is a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19. Simultaneous binding to CD19 and FcƳRIIB by obexelimab mimics a natural antigen-antibody complex and down-regulates B-cel...
Product Name : ZB012
Product Type : Antibody
Upfront Cash : Undisclosed
July 11, 2022
Lead Product(s) : Obexelimab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Enavate Sciences
Deal Size : $118.0 million
Deal Type : Series B Financing
Lead Product(s) : Veligrotug
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Viridian Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zenas BioPharma licensed the exclusive rights to develop, manufacture and commercialize ZB001 (Viridian VRDN-001) and other compounds targeting IGF-1R in non-oncology indications in the greater China area from Viridian Therapeutics in 2020.
Product Name : VRDN-001
Product Type : Antibody
Upfront Cash : Inapplicable
January 08, 2022
Lead Product(s) : Veligrotug
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Viridian Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable