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Find Clinical Drug Pipeline Developments & Deals by Zenas BioPharma

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                          Top Deals by Deal Size (USD bn)

                          01

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19. It is being investigated for Immunoglobulin G4-Related Disease.

                          Product Name : ZB012

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Obexelimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : The net proceeds to advance the clinical development of its lead asset ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19.

                          Product Name : ZB012

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          December 09, 2024

                          Lead Product(s) : Obexelimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Morgan Stanley

                          Deal Size : $225.0 million

                          Deal Type : Public Offering

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                          03

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : The net proceeds to advance the clinical development of its lead asset ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19.

                          Product Name : ZB012

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          September 19, 2024

                          Lead Product(s) : Obexelimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Morgan Stanley

                          Deal Size : $258.7 million

                          Deal Type : Public Offering

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                          04

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : The company plans to advance the clinical development of ZB012 (obexelimab), a novel bifunctional antibody with first-in-class potential that inhibits CD19-expressing B-cell lineages.

                          Product Name : ZB012

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          July 05, 2024

                          Lead Product(s) : Obexelimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : SR One Capital Management

                          Deal Size : $200.0 million

                          Deal Type : Series C Financing

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                          05

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : ZB-O12 (obexelimab) is an investigational Phase 3-stage, novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19 and generates an encouraging treatment effect in patients with multiple autoimmune diseases...

                          Product Name : ZB012

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 01, 2023

                          Lead Product(s) : Obexelimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : The collaboration aims to develop and commercialize ZB-O12 (obexelimab), an investigational bifunctional, non-cytolytic, humanized monoclonal antibody that binds CD19 and FcγRIIb, for autoimmune diseases in Japan, South Korea, Taiwan, Singapore, Hong Ko...

                          Product Name : ZB012

                          Product Type : Antibody

                          Upfront Cash : $50.0 million

                          May 09, 2023

                          Lead Product(s) : Obexelimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Bristol Myers Squibb

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : ZB001 (Viridian VRDN-001) is a differentiated humanized monoclonal antibody targeting insulin-like growth factor 1 receptor (IGF-1R) for the treatment of TED.

                          Product Name : VRDN-001

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          December 05, 2022

                          Lead Product(s) : Veligrotug

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Viridian Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : ZB-O12 (obexelimab) is a novel bifunctional antibody with first-in-class potential that inhibits B-cell lineages that express CD19. Simultaneous binding to CD19 and FcƳRIIB by obexelimab mimics a natural antigen-antibody complex and down-regulates B-cel...

                          Product Name : ZB012

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          July 11, 2022

                          Lead Product(s) : Obexelimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Enavate Sciences

                          Deal Size : $118.0 million

                          Deal Type : Series B Financing

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                          09

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : Zenas BioPharma licensed the exclusive rights to develop, manufacture and commercialize ZB001 (Viridian VRDN-001) and other compounds targeting IGF-1R in non-oncology indications in the greater China area from Viridian Therapeutics in 2020.

                          Product Name : VRDN-001

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 08, 2022

                          Lead Product(s) : Veligrotug

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Viridian Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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