
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Orion Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
X-Chem Expands Collaboration with Orion for Early Drug Discovery
Details : The collaboration reinforces X-Chem’s position as a partner with capabilities that extend well beyond screening, offering discovery solutions designed to accelerate success in small molecule drug.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
April 30, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Orion Pharma
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : TNX-4200
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Tonix Pharmaceuticals Holding Corp
Deal Size : Undisclosed
Deal Type : Collaboration
Tonix And X-Chem Collaborate to Develop AI-Based Broad-Spectrum Antivirals
Details : The collaboration aims to accelerate the development of Tonix’s oral broad-spectrum antivirals, including TNX-4200, an oral broad-spectrum antiviral program.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 08, 2024
Lead Product(s) : TNX-4200
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Tonix Pharmaceuticals Holding Corp
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Evotec
Deal Size : Undisclosed
Deal Type : Collaboration
Evotec and X-Chem Collaborate to Accelerate Early-Stage Drug Discovery
Details : The collaboration aims to accelerate early-stage drug discovery by using X-Chem’s DEL technology which streamlines hit finding by simultaneously screening up to billions of DNA-tagged compounds.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 05, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Evotec
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : iBRD9
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Recipient : Rumi Scientific
Deal Size : Undisclosed
Deal Type : Partnership
Details : Under the partnership, X-Chem will develop lead candidate, iBRD9, a BRD9 inhibitor, which is an epigenetic reader, as a novel therapeutic target for the treatment of Huntington’s Disease (HD).
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 05, 2023
Lead Product(s) : iBRD9
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Recipient : Rumi Scientific
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Relay Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
X-Chem Announces Achievement of Collaboration Milestone
Details : Under the collaboration, Relay Therapeutics utilized X-Chem’s DNA-Encoded Library platform to perform hit finding intended to discover molecules with differentiated pharmacological properties.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 05, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Relay Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Kymera Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership
X-Chem and Kymera Expand Existing Partnership
Details : The expanded partnership comprises 12 targets and grants Kymera exclusive rights to compounds discovered within the collaboration. X-Chem will apply its world-leading DEL platform to support Kymera’s discovery of small molecules and best-in-class prote...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 31, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Kymera Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership

X-Chem and Sironax Begin Neurodegenerative Disease Drug Discovery Research Partnership
Details : X-Chem will screen its unique DNA-encoded libraries against difficult-to-drug targets implicated in neurodegenerative disease to discover hits. In turn, Sironax will prosecute these hits into transformational medicines for degenerative disease.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 05, 2023

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : BioDuro
Deal Size : Undisclosed
Deal Type : Partnership
Details : Combined with BioDuro-Sundia’s one-stop drug discovery platform, customers can access world-class discovery technologies and support, covering hit identification and optimization, evaluation of lead and candidate compounds, and quickly advance to precl...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
August 07, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : BioDuro
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery
Recipient : Excelra
Deal Size : Undisclosed
Deal Type : Collaboration
X-Chem and Excelra's GOSTAR Join Forces to Advance Drug Discovery for Challenging Targets
Details : This synergistic new partnership between Excelra's GOSTAR and X-Chem's RosalindAI will enable to predict small molecules, chemical, biological, and physical properties, accelerating time and resource-intensive stages of drug discovery to preclinical cand...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
February 09, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery
Recipient : Excelra
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Sleep
Study Phase : Discovery
Sponsor : Centessa Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
X-Chem Announces Achievement of Milestone In Orexia Collaboration
Details : After successfully reaching this development milestone in the collaboration, Orexia exercised an option to exclusively license the orexin receptor type 2 (OX2R) program from X-Chem, which comprises multiple novel OX2R-specific small molecule orexin posit...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
July 22, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Sleep
Highest Development Status : Discovery
Sponsor : Centessa Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
