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    [{"orgOrder":0,"company":"Vor Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Inapplicable","leadProduct":"Gemtuzumab Ozogamicin","moa":"||CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Vor Biopharma \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Vor Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"Renaissance Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Public Offering","leadProduct":"VOR33","moa":"CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Inapplicable","leadProduct":"Gemtuzumab Ozogamicin","moa":"||CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Vor Biopharma \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Vor Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"Gemtuzumab Ozogamicin","moa":"||CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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Ozogamicin","moa":"||CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Vor Biopharma \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Vor Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Inapplicable","leadProduct":"Gemtuzumab Ozogamicin","moa":"||CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Vor Biopharma \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Vor Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"VCAR33","moa":"CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Vor Biopharma \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Vor Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Private Placement","leadProduct":"Gemtuzumab Ozogamicin","moa":"||CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor 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Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Inapplicable","leadProduct":"CD33 CAR-T Cell","moa":"||CD33","graph1":"Oncology","graph2":"Preclinical","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Vor Biopharma \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Vor Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"Gemtuzumab Ozogamicin","moa":"||CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Vor Biopharma \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Vor Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Private Placement","leadProduct":"VCAR33","moa":"CD33","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Vor Biopharma","amount2":0.059999999999999998,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.059999999999999998,"dosageForm":"Intravenous Infusion","sponsorNew":"Vor Biopharma \/ RA Capital Management","highestDevelopmentStatusID":"7","companyTruncated":"Vor Biopharma \/ RA Capital Management"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Protein","year":"2025","type":"Private Placement","leadProduct":"Telitacicept","moa":"BlyS\/APRIL","graph1":"Immunology","graph2":"Phase III","graph3":"Vor Biopharma","amount2":0.17999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Immunology","amount2New":0.17999999999999999,"dosageForm":"Subcutaneous Injection","sponsorNew":"Vor Biopharma \/ RA Capital Management","highestDevelopmentStatusID":"10","companyTruncated":"Vor Biopharma \/ RA Capital Management"},{"orgOrder":0,"company":"Vor Biopharma","sponsor":"RemeGen","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"CHINA","productType":"Protein","year":"2025","type":"Licensing Agreement","leadProduct":"Telitacicept","moa":"BlyS\/APRIL","graph1":"Immunology","graph2":"Phase III","graph3":"Vor Biopharma","amount2":4.1299999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Immunology","amount2New":4.1299999999999999,"dosageForm":"Subcutaneous Injection","sponsorNew":"Vor Biopharma \/ Vor Biopharma","highestDevelopmentStatusID":"10","companyTruncated":"Vor Biopharma \/ Vor Biopharma"}]

    Find Clinical Drug Pipeline Developments & Deals by Vor Biopharma

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                            01

                            Vor Biopharma

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                            Lead Product(s) : Telitacicept

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : RA Capital Management

                            Deal Size : $175.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Vor Bio Announces $175 Million Private Placement

                            Details : The proceeds will be used to fund the clinical development of Vor Bio pipeline, which includes RC18 (telitacicept), a novel, dual-target recombinant fusion protein.

                            Product Name : RC18

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            June 25, 2025

                            Lead Product(s) : Telitacicept

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : RA Capital Management

                            Deal Size : $175.0 million

                            Deal Type : Private Placement

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                            02

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : Telitacicept

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Recipient : RemeGen

                            Deal Size : $4,125.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Vor Bio Enters into Exclusive Global License Agreement with RemeGen

                            Details : Vor Bio receives ex-Greater China rights to develop and commercialize RC18 (telitacicept), a novel, dual-target recombinant fusion protein in global Phase 3 for generalized myasthenia gravis.

                            Product Name : RC18

                            Product Type : Protein

                            Upfront Cash : $45.0 million

                            June 25, 2025

                            Lead Product(s) : Telitacicept

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Recipient : RemeGen

                            Deal Size : $4,125.0 million

                            Deal Type : Licensing Agreement

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                            03

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : VCAR33

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : RA Capital Management

                            Deal Size : $55.6 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Vor Bio Announces $55.6 Million Private Placement

                            Details : Vor Bio will use the net proceeds to fund the clinical and preclinical development of its pipeline candidates, including VCAR33, which is being evaluated for the treatment of relapsed/refractory AML.

                            Product Name : VCAR33

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            December 27, 2024

                            Lead Product(s) : VCAR33

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : RA Capital Management

                            Deal Size : $55.6 million

                            Deal Type : Private Placement

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                            04

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vor Bio Shares Clinical Update on Shielded Transplants and FDA Support for Trial Design

                            Details : VOR33 (trem-cel) followed by Mylotarg is being investigated in patients with relapsed/refractory acute myeloid leukemia.

                            Product Name : VOR33

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 09, 2024

                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : VCAR33

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vor Bio Doses First AML Patient with VCAR33 (ALLO) and Provides Corporate Update

                            Details : VCAR33 is a CD33-directed CAR-T cell therapy made from healthy donor cells, under phase 1/2 development for treating relapsed/refractory acute myeloid leukemia.

                            Product Name : VCAR33

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            January 17, 2024

                            Lead Product(s) : VCAR33

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : Tremtelectogene Empogeditemcel,Ozogamicin

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First AML Patient Transplanted with Vor Bio Trem-cel Demonstrated Durable Engraftment Through Multiple Mylotar...

                            Details : Trem-cel (tremtelectogene empogeditemcel), is a genome-edited hematopoietic stem and progenitor allogeneic donor product candidate in order to remove the CD33 surface target protecting them from a targeted therapy post-transplant.

                            Product Name : Trem-cel

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            February 16, 2023

                            Lead Product(s) : Tremtelectogene Empogeditemcel,Ozogamicin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vor Bio to Present Clinical Data from First Patient Treated with Trem-cel at 2023 Tandem Meetings

                            Details : VOR33 (trem-cel) is our lead eHSC product candidate created by genetically modifying healthy donor HSCs in order to remove the CD33 surface target which is involved in causing AML and other blood related cancers thus, protecting them from a targeted ther...

                            Product Name : VOR33

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            January 19, 2023

                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vor Bio Demonstrates Potential of Base and Sequential Multiplex Editing of Hematopoietic Stem Cells for Next-g...

                            Details : VOR33 (Engineered Hematopoietic Stem Cell) is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell therapy product that lacks the CD33 myeloid protein.

                            Product Name : VOR33

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            November 10, 2022

                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vor Bio Successfully Demonstrates Multiplex Editing of Hematopoietic Stem Cells for Next-generation AML Treatm...

                            Details : The pre-clinical data of VOR33 (Engineered Hematopoietic Stem Cell), demonstrates that multiplex deletion by CRISPR/Cas9 of CD33 and CLL-1 from human CD34+ HSPCs maintained cell function and persisted long-term post engraftment in vivo.

                            Product Name : VOR33

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            October 06, 2022

                            Lead Product(s) : VOR33,Ozogamicin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Vor Biopharma

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                            Vor Biopharma

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                            Lead Product(s) : Tremtelectogene Empogeditemcel,Ozogamicin

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Evercore ISI

                            Deal Size : $65.8 million

                            Deal Type : Public Offering

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                            Vor Bio Prices Underwritten Offering of Common Stock and Concurrent Private Placement for Aggregate Proceeds o...

                            Details : Vor Bio intends to use the net proceeds from the offering and concurrent private placement primarily to fund the continued clinical development of Trem-cel (tremtelectogene empogeditemcel) and pipeline products and for working capital and general corpora...

                            Product Name : Trem-cel

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 12, 2022

                            Lead Product(s) : Tremtelectogene Empogeditemcel,Ozogamicin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Evercore ISI

                            Deal Size : $65.8 million

                            Deal Type : Public Offering

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