Lead Product(s) : Vonafexor
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Vesalius Biocapital
Deal Size : $36.8 million
Deal Type : Series C Financing
ENYO Completes Series C to Advance Phase 2 Study in Alport Syndrome
Details : The proceeds will fund the ongoing ALPESTRIA-1 study evaluating EYP001 (vonafexor), a highly selective and oral FXR agonist, in patients with Alport syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 12, 2025
Lead Product(s) : Vonafexor
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Vesalius Biocapital
Deal Size : $36.8 million
Deal Type : Series C Financing
Lead Product(s) : Vonafexor
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Vonafexor is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Renal Insufficiency, Chronic.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 23, 2025
Lead Product(s) : Vonafexor
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Vonafexor
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1)
Details : Vonafexor is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Nephritis, Hereditary.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 22, 2024
Lead Product(s) : Vonafexor
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Vonafexor
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : OrbiMed Advisors
Deal Size : $42.5 million
Deal Type : Series C Financing
ENYO Pharma Secures €39M in Series C and FDA Clearance for Vonafexor
Details : Financing will support the Phase 2 Alpestria-1 study and profiling of EYP001 (vonafexor), a selective NR1H4 agonist, in Autosomal Dominant Polycystic Kidney Disease (ADPKD).
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 03, 2024
Lead Product(s) : Vonafexor
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : OrbiMed Advisors
Deal Size : $42.5 million
Deal Type : Series C Financing
Lead Product(s) : Vonafexor
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Vonafexor is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 22, 2019
Lead Product(s) : Vonafexor
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Vonafexor
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : CPR Pharma Services
Deal Size : Inapplicable
Deal Type : Inapplicable
Drug Drug Interaction Study for EYP001 With Entecavir
Details : EYP001 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hepatitis B, Chronic.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 19, 2018
Lead Product(s) : Vonafexor
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : CPR Pharma Services
Deal Size : Inapplicable
Deal Type : Inapplicable