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    [{"orgOrder":0,"company":"PTC Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"Volanesorsen","moa":"Apolipoprotein C-III mRNA 3'UTR","graph1":"Rare Diseases and Disorders","graph2":"Approved FDF","graph3":"PTC Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"PTC Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"PTC Therapeutics \/ Inapplicable"}]

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                            01

                            PTC Therapeutics

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                            ChemOutsourcing
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                            PTC Therapeutics

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                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Brazilian Regulatory Authority Grants Approval for Waylivra™ for Familial Partial Lipodystrophy

                            Details : Waylivra (volanesorsen), an antisense oligonucleotide designed to inhibit the formation of apoC-III, is a product of Ionis Pharmaceuticals, Inc.'s proprietary antisense technology. Waylivra has received conditional marketing approval in the EU as a treat...

                            Product Name : Waylivra

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            January 12, 2022

                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Akcea Therapeutics

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                            ChemOutsourcing
                            Not Confirmed

                            Akcea Therapeutics

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                            ChemOutsourcing
                            Not Confirmed
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                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Genetic Disease

                            Study Phase : Undisclosed

                            Sponsor : CaligorRx, Inc.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Volanesorsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            June 01, 2018

                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Undisclosed

                            Sponsor : CaligorRx, Inc.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Ionis Pharmaceuticals

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                            ChemOutsourcing
                            Not Confirmed

                            Ionis Pharmaceuticals

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                            ChemOutsourcing
                            Not Confirmed
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                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Akcea Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate the Effect of Volanesorsen on Cardiac Repolarization Conducted in Healthy Volunteers

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            September 22, 2016

                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Akcea Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Akcea Therapeutics

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                            ChemOutsourcing
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                            Akcea Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Ionis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familia...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            January 18, 2016

                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Ionis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Akcea Therapeutics

                            U.S.A arrow
                            ChemOutsourcing
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                            Akcea Therapeutics

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                            ChemOutsourcing
                            Not Confirmed
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                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase II/ Phase III

                            Sponsor : Ionis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial Li...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            August 19, 2015

                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Ionis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Ionis Pharmaceuticals

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                            ChemOutsourcing
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                            Ionis Pharmaceuticals

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                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Akcea Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            November 24, 2014

                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Akcea Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Ionis Pharmaceuticals

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                            ChemOutsourcing
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                            Ionis Pharmaceuticals

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                            ChemOutsourcing
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                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Akcea Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The APPROACH Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronem...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            August 07, 2014

                            Lead Product(s) : Volanesorsen

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Akcea Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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