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    [{"orgOrder":0,"company":"Valneva","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Valneva Reports Positive End-of-Phase 2 Chikungunya Meeting with the U.S. FDA; Sets Stage for Phase 3 Study","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase II","country":"FRANCE","productType":"Vaccine","productStatus":"New Molecular Entity","date":"March 2020","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Valneva","sponsor":"Instituto Butantan","pharmaFlowCategory":"D","amount":"$23.4 million","upfrontCash":"Undisclosed","newsHeadline":"Valneva and Instituto Butantan Sign Final Agreement on Single-Shot Chikungunya Vaccine for Low and Middle Income Countries","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase III","country":"FRANCE","productType":"Vaccine","productStatus":"New 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              Valneva

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              EMA Accepts Valneva's Chikungunya Vaccine Marketing Authorization Application for Accelerated Assessment

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus which was recently approved by USFDA. It has been designed by deleting a part of the chikungunya virus genome.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Approved Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable November 27, 2023

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              Valneva

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              Valneva Reports Positive Pivotal Phase 3 Immunogenicity Data in Adolescents for its Single-Shot Chikungunya Vaccine Candidate

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus and company believes the regulatory review could be completed by mid-2024.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable November 13, 2023

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              Valneva

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              Valneva Submits Chikungunya Vaccine Marketing Application to EMA and Announces CHMP Accelerated Assessment

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus, which has spread to over 110 countries. It has been designed by deleting a part of the chikungunya virus genome.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable October 25, 2023

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              Valneva

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              Health Canada Accepts Valneva’s Chikungunya Vaccine License Application for Review

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus and company believes the regulatory review could be completed by mid-2024.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 29, 2023

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              Valneva

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              Valneva Reports Positive Initial Phase 3 Safety Data in Adolescents for its Single-Shot Chikungunya Vaccine Candidate

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus, which has spread to over 110 countries. It has been designed by deleting a part of the chikungunya virus genome.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 28, 2023

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              Valneva

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              Valneva Announces Extension of Existing Loan Agreement

              Details:

              The financing will be used to further invest in R&D, as well as continued market access preparations and potential commercialization of Valneva’s VLA1553, a live-attenuated vaccine candidate for active immunisation and prevention of disease caused by chikungunya virus.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Deerfield Management Company

              Deal Size: Undisclosed Upfront Cash: Undisclosed

              Deal Type: Financing August 17, 2023

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              Valneva

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              Valneva Files for Chikungunya Vaccine Authorization with Health Canada

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus, If approved, VLA1553 would expand Valneva’s existing commercial vaccines portfolio.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable May 30, 2023

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              Valneva

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              FDA Accepts Valneva’s Chikungunya Vaccine License Application for Priority Review

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus, which has spread to over 100 countries. It has been designed by deleting a part of the chikungunya virus genome.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable February 20, 2023

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              Valneva

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              Pfizer and Valneva Issue Update on Phase 3 Clinical Trial Evaluating Lyme Disease Vaccine Candidate VLA15

              Details:

              VLA15 is the only Lyme disease vaccine candidate under development. It is a multivalent protein subunit vaccine which targets the outer surface protein A (OspA) of borrelia burgdorferi, the bacteria that cause lyme disease.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Pfizer Inc

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable February 17, 2023

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              Valneva

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              Valneva Completes Enrollment for Adolescent Phase 3 Trial of Single-Shot Chikungunya Vaccine Candidate

              Details:

              VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus, which has spread to over 100 countries. It has been designed by deleting a part of the chikungunya virus genome.

              Lead Product(s): VLA1553

              Therapeutic Area: Infections and Infectious Diseases Product Name: VLA1553

              Highest Development Status: Phase III Product Type: Vaccine

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable February 14, 2023

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