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    [{"orgOrder":0,"company":"Northwestern University","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Targeted Drug Combo Attacks Breast Cancer Brain Metastases in Mice","therapeuticArea":"Oncology","highestDevelopmentStatus":"Preclinical","country":"","productType":"Small molecule","productStatus":"New Molecular Entity","date":"August 2020","url1":"","url2":"","graph1":"Oncology","graph2":"Preclinical"},{"orgOrder":0,"company":"Merus","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Merus Presents Updated Analysis of Zenocutuzumab, Trastuzumab, and Vinorelbine in Patients with HER2+ Metastatic Breast Cancer at the San Antonio Breast Cancer Symposium","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase II","country":"NETHERLANDS","productType":"Large molecule","productStatus":"New Molecular Entity","date":"December 2021","url1":"","url2":"","graph1":"Oncology","graph2":"Phase II"}]

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    Vinorelbine Tartrate

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              Merus

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              Merus Presents Updated Analysis of Zenocutuzumab, Trastuzumab, and Vinorelbine in Patients with HER2+ Metastatic Breast Cancer at the San Antonio Breast Cancer Symposium

              Details:

              Zenocutuzumab (MCLA-128) in combination with trastuzumab and vinorelbine in patients met primary endpoint of Clinical Benefit Rate at 24 weeks and showed clinically meaningful activity after 3 lines of anti-HER2 therapies including T-DM1.

              Lead Product(s): Zenocutuzumab,Trastuzumab,Vinorelbine Tartrate

              Therapeutic Area: Oncology Product Name: MCLA-128

              Highest Development Status: Phase II Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable December 10, 2021

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              Northwestern University

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              Targeted Drug Combo Attacks Breast Cancer Brain Metastases in Mice

              Details:

              The two drugs are tubulin inhibitor, vinorelbine, approved by the U.S. Food and Drug Administration (FDA) and available in clinics, and bromodomain inhibitor, I-BET-762, FDA approved for clinical trials.

              Lead Product(s): Molibresib,Vinorelbine Tartrate

              Therapeutic Area: Oncology Product Name: I-BET-762

              Highest Development Status: Preclinical Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 26, 2020

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              Minakem Vinorelbine Tartrate New
              ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.
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