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            VTX958, an oral, selective clinical-stage tyrosine kinase type 2 inhibitor that it believes has the potential to address a broad range of immune-mediated diseases, such as psoriasis, inflammatory bowel disease, psoriatic arthritis, and lupus.

            Lead Product(s): VTX958

            Therapeutic Area: Immunology Product Name: VTX958

            Highest Development Status: Phase I Product Type: Small molecule

            Recipient: Ventyx Biosciences

            Deal Size: $100.0 million Upfront Cash: Undisclosed

            Deal Type: Public Offering September 29, 2021

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            Horizon Therapeutics gets UPLIZNA, first and only FDA-approved B-cell-depleting humanized monoclonal antibody for the treatment of neuromyelitis optica spectrum disorder.

            Lead Product(s): Inebilizumab

            Therapeutic Area: Immunology Product Name: Uplizna

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Horizon Therapeutics

            Deal Size: $3,005.0 million Upfront Cash: $3,005.0 million

            Deal Type: Acquisition March 15, 2021

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            Horizon adds UPLIZNA® (inebilizumab-cdon) to its commercial rare disease medicine portfolio. The acquisition Adds deep, mid-stage biologics pipeline focused primarily on autoimmune and severe inflammatory diseases.

            Lead Product(s): Inebilizumab

            Therapeutic Area: Immunology Product Name: Uplizna

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Horizon Therapeutics

            Deal Size: $3,005.0 million Upfront Cash: $3,005.0 million

            Deal Type: Acquisition February 01, 2021

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            First poster will highlights study results in AQP4-IgG seronegative patients in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.

            Lead Product(s): Inebilizumab

            Therapeutic Area: Immunology Product Name: Uplizna

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 03, 2020

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            The interim findings indicated safety and tolerability comparable to placebo control across all cohorts, potent depletion of pDC both in peripheral blood and in inflamed CLE skin lesion biopsies in cohort 2, and dose-dependent reduction in CLASI after treatment with VIB7734.

            Lead Product(s): VIB7734

            Therapeutic Area: Immunology Product Name: Undisclosed

            Highest Development Status: Phase I Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 14, 2020

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