Active Filter(s):
Details:
VTX958, an oral, selective clinical-stage tyrosine kinase type 2 inhibitor that it believes has the potential to address a broad range of immune-mediated diseases, such as psoriasis, inflammatory bowel disease, psoriatic arthritis, and lupus.
Lead Product(s): VTX958
Therapeutic Area: Immunology Product Name: VTX958
Highest Development Status: Phase I Product Type: Small molecule
Recipient: Ventyx Biosciences
Deal Size: $100.0 million Upfront Cash: Undisclosed
Deal Type: Public Offering September 29, 2021
Details:
Horizon Therapeutics gets UPLIZNA, first and only FDA-approved B-cell-depleting humanized monoclonal antibody for the treatment of neuromyelitis optica spectrum disorder.
Lead Product(s): Inebilizumab
Therapeutic Area: Immunology Product Name: Uplizna
Highest Development Status: Approved Product Type: Large molecule
Partner/Sponsor/Collaborator: Horizon Therapeutics
Deal Size: $3,005.0 million Upfront Cash: $3,005.0 million
Deal Type: Acquisition March 15, 2021
Details:
Horizon adds UPLIZNA® (inebilizumab-cdon) to its commercial rare disease medicine portfolio. The acquisition Adds deep, mid-stage biologics pipeline focused primarily on autoimmune and severe inflammatory diseases.
Lead Product(s): Inebilizumab
Therapeutic Area: Immunology Product Name: Uplizna
Highest Development Status: Approved Product Type: Large molecule
Partner/Sponsor/Collaborator: Horizon Therapeutics
Deal Size: $3,005.0 million Upfront Cash: $3,005.0 million
Deal Type: Acquisition February 01, 2021
Details:
First poster will highlights study results in AQP4-IgG seronegative patients in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
Lead Product(s): Inebilizumab
Therapeutic Area: Immunology Product Name: Uplizna
Highest Development Status: Approved Product Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 03, 2020
Details:
The interim findings indicated safety and tolerability comparable to placebo control across all cohorts, potent depletion of pDC both in peripheral blood and in inflamed CLE skin lesion biopsies in cohort 2, and dose-dependent reduction in CLASI after treatment with VIB7734.
Lead Product(s): VIB7734
Therapeutic Area: Immunology Product Name: Undisclosed
Highest Development Status: Phase I Product Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 14, 2020