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    [{"orgOrder":0,"company":"VectorY","sponsor":"MRL Ventures Fund","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Antibody, Unconjugated","year":"2023","type":"Series A Financing","leadProduct":"VTx-002","moa":"Sphingosine-1-phosphate receptor 1 (S1PR1)","graph1":"Neurology","graph2":"Phase II","graph3":"VectorY","amount2":0.14000000000000001,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0.14000000000000001,"dosageForm":"Tablet","sponsorNew":"VectorY \/ MRL Ventures Fund","highestDevelopmentStatusID":"8","companyTruncated":"VectorY \/ MRL Ventures Fund"},{"orgOrder":0,"company":"VectorY","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Antibody, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"VTx-002","moa":"Sphingosine-1-phosphate receptor 1 (S1PR1)","graph1":"Neurology","graph2":"Phase II","graph3":"VectorY","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"VectorY \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"VectorY \/ Undisclosed"},{"orgOrder":0,"company":"VectorY","sponsor":"UMC Utrecht","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Antibody, Unconjugated","year":"2024","type":"Collaboration","leadProduct":"VTx-002","moa":"Sphingosine-1-phosphate receptor 1 (S1PR1)","graph1":"Neurology","graph2":"Phase II","graph3":"VectorY","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"VectorY \/ UMC Utrecht","highestDevelopmentStatusID":"8","companyTruncated":"VectorY \/ UMC Utrecht"},{"orgOrder":0,"company":"VectorY","sponsor":"University Medical Center","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Antibody, Unconjugated","year":"2024","type":"Collaboration","leadProduct":"VTx-002","moa":"Sphingosine-1-phosphate receptor 1 (S1PR1)","graph1":"Neurology","graph2":"Phase II","graph3":"VectorY","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"VectorY \/ University Medical Center","highestDevelopmentStatusID":"8","companyTruncated":"VectorY \/ University Medical Center"},{"orgOrder":0,"company":"VectorY","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"AAV-VecTabs","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"VectorY","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"VectorY \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"VectorY \/ Undisclosed"},{"orgOrder":0,"company":"VectorY","sponsor":"Forbion","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Undisclosed","year":"2021","type":"Financing","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"VectorY","amount2":0.040000000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.040000000000000001,"dosageForm":"Undisclosed","sponsorNew":"VectorY \/ Forbion","highestDevelopmentStatusID":"4","companyTruncated":"VectorY \/ Forbion"},{"orgOrder":0,"company":"VectorY","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"NETHERLANDS","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"VectorY","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"VectorY \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"VectorY \/ Undisclosed"},{"orgOrder":0,"company":"VectorY","sponsor":"Annogen","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Undisclosed","year":"2023","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"VectorY","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"VectorY \/ Annogen","highestDevelopmentStatusID":"4","companyTruncated":"VectorY \/ Annogen"},{"orgOrder":0,"company":"VectorY","sponsor":"Wageningen University","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"NETHERLANDS","productType":"Undisclosed","year":"2022","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"VectorY","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"VectorY \/ Wageningen University","highestDevelopmentStatusID":"4","companyTruncated":"VectorY \/ Wageningen University"},{"orgOrder":0,"company":"VectorY","sponsor":"Shape Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2025","type":"Licensing Agreement","leadProduct":"VTx-003","moa":"\u03b1v\u03b21","graph1":"Genetic Disease","graph2":"Discovery","graph3":"VectorY","amount2":1.2,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Genetic Disease","amount2New":1.2,"dosageForm":"Undisclosed","sponsorNew":"VectorY \/ VectorY","highestDevelopmentStatusID":"2","companyTruncated":"VectorY \/ VectorY"}]

    Find Clinical Drug Pipeline Developments & Deals by VectorY

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                            01

                            VectorY

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                            Lead Product(s) : VTx-003

                            Therapeutic Area : Genetic Disease

                            Study Phase : Discovery

                            Recipient : Shape Therapeutics

                            Deal Size : $1,200.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            VectorY and Shape Therapeutics Announce Option and License Agreement

                            Details : VectorY gains an exclusive option to evaluate Shape’s deep-brain penetrating AAV capsid for vectorized antibody payloads, including VTx-003 in Huntington’s Disease.

                            Product Name : VTx-003

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            September 18, 2025

                            Lead Product(s) : VTx-003

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Discovery

                            Recipient : Shape Therapeutics

                            Deal Size : $1,200.0 million

                            Deal Type : Licensing Agreement

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                            02

                            VectorY

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                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : University Medical Center

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            UMC Utrecht and VectorY collaborate to identify biomarkers of ALS in new study

                            Details : The collaboration aims to support VectorY’s lead program, VTx-002, which is being evaluated in the early-stage clinical trial studies for the treatment of ALS.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            June 18, 2024

                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : University Medical Center

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            03

                            VectorY

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                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : UMC Utrecht

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            UMC Utrecht and VectorY Therapeutics collaborate in ALS Biomarker Study

                            Details : VTx-002, a vectorized antibody that selectively clears misfolded and aggregated TDP-43 from the cytoplasm of neuronal cells, is being developed for the treatment of Amyotrophic Lateral Sclerosis.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            June 17, 2024

                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : UMC Utrecht

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            VectorY

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                            VectorY

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                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : MRL Ventures Fund

                            Deal Size : $138.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            VectorY Raises €129 Million ($138 Million) Series A Financing to Advance Vectorized Antibody Programs in Neu...

                            Details : VectorY will use the proceeds to support the clinical development of VTx-002 (OPL-002), its lead vectorized antibody program targeting TDP-43 for the treatment of amyotrophic lateral sclerosis.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            November 13, 2023

                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : MRL Ventures Fund

                            Deal Size : $138.0 million

                            Deal Type : Series A Financing

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                            05

                            VectorY

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery

                            Sponsor : Annogen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            VectorY and Annogen Announce Research Collaboration for the Development of CNS-cell Specific Promoters

                            Details : Under the terms of the agreement, VectorY and Annogen will work on novel tailored cell-specific promoters to enhance VectorY’s transformative AAV-vectorized antibody platform and its potential to yield disease-modifying treatments for neurodegenerative...

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 19, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery

                            Sponsor : Annogen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

                            VectorY

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            VectorY to Present Poster on Huntington’s Preclinical Data at the Hereditary Disease Foundation, August 24-2...

                            Details : VecTabs, which are secreted- or intracellular-antibody fragments that are AAV-vectorized and delivered to neurons and/or astrocytes, have previously been shown to efficiently target such misfolded proteins (TDP-43) and toxic lipids (oxPL).

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            August 23, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            VectorY

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                            Lead Product(s) : AAV-VecTabs

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            VectorY Presents New Pre-clinical data at the European Network for the Cure of ALS (ENCALS)

                            Details : The new data demonstrate therapeutic potential and versatility of VectorY’s VecTab platform technology, enabling development of secreted or intracellular antibody fragments that are AAV-VecTabs delivered to neurons and/or astrocytes, in vitro and in vi...

                            Product Name : AAV-VecTabs

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            June 02, 2022

                            Lead Product(s) : AAV-VecTabs

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            VectorY

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                            VectorY

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                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            VectorY Announces Preclinical Data on TDP-43 and Oxidized Phospholipids at American Society of Gene and Cell T...

                            Details : VTx-002, reduce TDP-43 pathological aggregates for treating ALS, TAR-DNA binding protein-43 is necessary for correct processing and transport of multiple mRNA’s that are essential for neuronal survival.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            May 18, 2022

                            Lead Product(s) : VTx-002

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            VectorY

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                            VectorY

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Study Phase : Undisclosed

                            Sponsor : Wageningen University

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Wageningen University & Research and VectorY to Jointly Develop Novel Production Technologies for Safer and Mo...

                            Details : The strategy is based on the baculovirus expression system, which is already widely used for vaccine production and uses viruses that can only infect insect cells, the so-called baculoviruses.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 25, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Undisclosed

                            Sponsor : Wageningen University

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            10

                            VectorY

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Forbion

                            Deal Size : $36.7 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            VectorY Raises €31 Million in Seed Financing to Develop Next-Generation Gene Therapies Aimed at Muscular and...

                            Details : Proceeds to establish pre-clinical proof of concept for vectorized antibodies in ALS and Alzheimer’s and to further expand the team.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            June 15, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Forbion

                            Deal Size : $36.7 million

                            Deal Type : Financing

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