
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Notable Labs
Deal Size : Undisclosed
Deal Type : Merger
Notable Labs Closes Merger Transaction with VBL Therapeutics
Details : The Merger will focus on developing new precision medicines through Notable’s proprietary Predictive Precision Medicines Platform. NBL-001 (volasertib) is derived from PPMP and is a highly potent PLK1 inhibitor inducing cell cycle arrest and apoptosis ...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 16, 2023
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Notable Labs
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Notable Labs
Deal Size : Undisclosed
Deal Type : Merger
VBL Therapeutics and Notable Labs Announce Definitive Merger Agreement
Details : The Merger will create a clinical-stage therapeutic platform company developing new precision medicines through Notable’s proprietary PPMP. NBL-001 (volasertib) is derived from PPMP and is a highly potent PLK1 inhibitor inducing cell cycle arrest and a...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
February 23, 2023
Lead Product(s) : Volasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Notable Labs
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OVAL was an international, Phase 3, randomized, double-blind, placebo-controlled, clinical trial comparing a combination of ofra-vec (ofranergene obadenovec; VB-111) plus paclitaxel to placebo plus paclitaxel in adult patients with recurrent platinum-res...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
July 19, 2022
Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : VB-601
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
VBL Therapeutics to Participate in Upcoming Scientific and Industry Conferences in May
Details : VBL is advancing drug development program that is exploring the potential of MOSPD2 (motile sperm domain-containing protein 2), a protein that VBL has identified as a key regulator of cell motility, as a therapeutic target for inflammatory diseases.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 03, 2022
Lead Product(s) : VB-601
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ofranergene Obadenovec is an investigational anti-cancer, gene-therapy agent in development to treat a wide range of solid tumors. Ofra-vec is a unique biologic agent designed to use a dual mechanism to target solid tumors.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
April 26, 2022
Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Phase 3 OVAL trial enrolled 409 patients globally, comparing a combination of VB-111 (GOG-3018), a unique biologic agent designed to use a dual mechanism to target solid tumors, and paclitaxel to placebo plus paclitaxel, in adult patients with ovarian ca...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
March 08, 2022
Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : EIC Accelerator
Deal Size : $20.0 million
Deal Type : Funding
VBL Therapeutics Selected for €17.5 Million of Funding from Horizon Europe EIC Accelerator Program
Details : The funds from the EIC will be used to support clinical development, Chemistry Manufacturing and Controls (CMC), and pre-commercialization activities and will support the ongoing Phase 3 OVAL registration-enabling clinical trial of ofra-vec (VB-111) in o...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
December 20, 2021
Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : EIC Accelerator
Deal Size : $20.0 million
Deal Type : Funding

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Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The OVAL trial evaluating VB-111 in ovarian cancer is planned to enroll approximately 400 patients globally and nearly 80% of patients have already been recruited.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
August 30, 2021
Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OVAL is an international Phase 3 randomized pivotal registration enabling clinical trial that compares a combination of VB-111 and paclitaxel to placebo plus paclitaxel, in patients with platinum resistant ovarian cancer.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
June 15, 2021
Lead Product(s) : Ofranergene obadenovec,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : VB-201
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study to Evaluate the Efficacy and Safety of VB-201 in Patients With COVID-19
Details : VB-201 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of COVID-19.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 02, 2021
Lead Product(s) : VB-201
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
