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    [{"orgOrder":0,"company":"Vivoryon Therapeutics","sponsor":"Hauck Aufh\u00e4user Lampe Privatbank AG","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"GERMANY","productType":"Other Small Molecule","year":"2023","type":"Private Placement","leadProduct":"Varoglutamstat","moa":"Amyloid-beta","graph1":"Neurology","graph2":"Phase II","graph3":"Vivoryon Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Vivoryon Therapeutics \/ Hauck Aufh\u00e4user Lampe Privatbank AG","highestDevelopmentStatusID":"8","companyTruncated":"Vivoryon Therapeutics \/ Hauck Aufh\u00e4user Lampe Privatbank AG"},{"orgOrder":0,"company":"Vivoryon Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"GERMANY","productType":"Other Small 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Molecule","year":"2020","type":"Inapplicable","leadProduct":"Varoglutamstat","moa":"Amyloid-beta","graph1":"Neurology","graph2":"Phase II","graph3":"Vivoryon Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Vivoryon Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Vivoryon Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Vivoryon Therapeutics","sponsor":"Nordic Bioscience","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"GERMANY","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Varoglutamstat","moa":"Amyloid-beta","graph1":"Neurology","graph2":"Phase II","graph3":"Vivoryon Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Vivoryon Therapeutics \/ Nordic Bioscience","highestDevelopmentStatusID":"8","companyTruncated":"Vivoryon Therapeutics \/ Nordic Bioscience"},{"orgOrder":0,"company":"Vivoryon Therapeutics","sponsor":"Yorkville","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"GERMANY","productType":"Other Small Molecule","year":"2025","type":"Financing","leadProduct":"Varoglutamstat","moa":"QPCT\/QPCTL","graph1":"Nephrology","graph2":"Phase I","graph3":"Vivoryon Therapeutics","amount2":0.02,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Nephrology","amount2New":0.02,"dosageForm":"Oral Tablet","sponsorNew":"Vivoryon Therapeutics \/ Yorkville","highestDevelopmentStatusID":"6","companyTruncated":"Vivoryon Therapeutics \/ Yorkville"}]

    Find Clinical Drug Pipeline Developments & Deals for Varoglutamstat

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                            01

                            Vivoryon Therapeutics

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                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Nephrology

                            Study Phase : Phase I

                            Sponsor : Yorkville

                            Deal Size : $17.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Vivoryon Therapeutics N.V. Signs Financing Agreement for up to EUR 15 Million

                            Details : The financing aims to advance the clinical development of PQ912 (varoglutamstat) is a selective inhibitor of QPCT/QPCTL with therapeutic potential in indications including

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            April 24, 2025

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase I

                            Sponsor : Yorkville

                            Deal Size : $17.0 million

                            Deal Type : Financing

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                            02

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Presents Phase 2 Data Supporting Varoglutamstat’s Potential in Kidney Function

                            Details : PQ912 (varoglutamstat) is designed to prevent N3pE- Abeta formation, a key driver of AD pathology. It is being developed for the treatment of alzheimer's disease.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 09, 2024

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Reports Unique Effects of Varoglutamstat on Kidney Function in Diabetes

                            Details : PQ912 (varoglutamstat) is designed to prevent N3pE- Abeta formation, a key driver of AD pathology. It is being developed for the treatment of alzheimer's disease.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 18, 2024

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Updates on VIVIAD Phase 2b Study of Varoglutamstat in Early Alzheimer’s

                            Details : PQ912 (varoglutamstat) is designed to prevent N3pE- Abeta formation, a key driver of AD pathology. It is being developed for the treatment of alzheimer's disease.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 03, 2024

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Therapeutics N.V. Provides Comprehensive Progress Report for Ongoing Varoglutamstat Clinical Program ...

                            Details : PQ912 (varoglutamstat) is designed to prevent N3pE- Abeta formation, a key driver of AD pathology. It is being developed for the treatment of alzheimer's disease.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 26, 2023

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Therapeutics N.V. Reports Positive Outcome from Independent Data Safety Monitoring Board with Unanimo...

                            Details : PQ912 (varoglutamstat) is designed to prevent N3pE- Abeta formation, a key driver of AD pathology. It is being developed for the treatment of alzheimer's disease.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 23, 2023

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Hauck Aufhäuser Lampe Privatbank AG

                            Deal Size : $26.8 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Vivoryon Therapeutics Successfully Completes Private Placement Raising EUR 25 Million

                            Details : Vivoryon intends to use the net proceeds to accelerate the ongoing clinical development of its lead product candidate PQ912 (varoglutamstat), currently in Phase 2 in Europe and the United States for the treatment of patients with Alzheimer’s disease.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 26, 2023

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Hauck Aufhäuser Lampe Privatbank AG

                            Deal Size : $26.8 million

                            Deal Type : Private Placement

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                            08

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Therapeutics N.V. Provides Progress Update on Varoglutamstat Clinical Development for the Treatment o...

                            Details : PQ912 (varoglutamstat) is designed to prevent N3pE- Abeta formation, a key driver of AD pathology. It is being developed for the treatment of alzheimer's disease.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 28, 2023

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Nordic Bioscience

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Therapeutics N.V. Presents Key Phase 2b Data at AAIC 2022 Showing that Varoglutamstat is Well Tolerat...

                            Details : Varoglutamstat (PQ912) is a differentiated oral small-molecule targeting the toxic Abeta species N3pE which is being developed as disease-modifying therapy and is designed to target AD pathology upstream of Abeta-antibody focused approaches.

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 31, 2022

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Nordic Bioscience

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Vivoryon Therapeutics

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                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vivoryon Develops New Phase IIa Alzheimer’s Trial Design

                            Details : Vivoryon and the Alzheimer’s Disease Cooperative Study have developed a new trial design for Phase 2a Alzheimer’s trial in the US as a stage gate to Phase 2b. Vivoryon’s lead candidate, PQ912, got approval of the International Nonproprietary Name (...

                            Product Name : PQ912

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 26, 2020

                            Lead Product(s) : Varoglutamstat

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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