Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Trethera Secures New License, Strengthening TRE-515 Intellectual Property Portfolio
Details : Under the licensing agreement, Trethera will holds the exclusive rights for the clinical development of TRE-515, which is beingt evaluated for the treatment of neoplasms.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 03, 2025
Trethera, UCLA Show TRE-515 Controls Immune Activation in Multiple Sclerosis
Details : TRE-515, targets the enzyme deoxycytidine kinase (dCK), currently being investigated for the treatment of multiple sclerosis.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 25, 2025
Lead Product(s) : TRE-515
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Trethera
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : TRE-515 is a first-in-class clinical stage drug that inhibits deoxycytidine kinase (dCK), the rate-limiting enzyme in the nucleoside salvage pathway, one of two biosynthetic pathways that generate DNA precursors.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 09, 2022
Lead Product(s) : TRE-515
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Trethera
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : National Institutes of Health
Deal Size : $14.0 million
Deal Type : Funding
UCLA Receives Nearly $14 million from NIH to Investigate Gene Therapy to Combat HIV
Details : The five-year grant, part of an NIH effort to develop gene-engineering technologies to cure HIV/AIDS, will fund a collaboration among UCLA; CSL-Behring, to investigate and further develop an immunotherapy known as CAR T.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 15, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : National Institutes of Health
Deal Size : $14.0 million
Deal Type : Funding
Lead Product(s) : Ibudilast
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Recipient : Medicinova
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : This study was a randomized, double-blind, placebo-controlled Phase 2 trial to evaluate the effect of 14 days of ibudilast treatment on heavy drinking days and alcohol neural cue reactivity.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 08, 2020
Lead Product(s) : Ibudilast
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Recipient : Medicinova
Deal Size : Inapplicable
Deal Type : Inapplicable