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[{"orgOrder":0,"company":"Tubulis","sponsor":"BioMedPartners","pharmaFlowCategory":"D","amount":"$12.5 million","upfrontCash":"Undisclosed","newsHeadline":"Tubulis Raises \u20ac10.7 M Series A to Advance Development of a New Generation of Antibody-Drug Conjugates","therapeuticArea":"Oncology","highestDevelopmentStatus":"Preclinical","country":"GERMANY","productType":"Large molecule","productStatus":"New Molecular Entity","date":"July 2020","url1":"","url2":"","graph1":"Oncology","graph2":"Preclinical"},{"orgOrder":0,"company":"Tubulis","sponsor":"WuXi Biologics","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Tubulis Partners with WuXi Biologics and WuXi STA to Advance New Generation of Antibody-Drug Conjugates","therapeuticArea":"Oncology","highestDevelopmentStatus":"Preclinical","country":"GERMANY","productType":"Large molecule","productStatus":"New Molecular Entity","date":"December 2020","url1":"","url2":"","graph1":"Oncology","graph2":"Preclinical"},{"orgOrder":0,"company":"Tubulis","sponsor":"Andera Partners","pharmaFlowCategory":"D","amount":"$63.0 million","upfrontCash":"Undisclosed","newsHeadline":"Andera Partners Supports Tubulis in a \u20ac60 Million Series B Financing to Accelerate the Development of its ADCs","therapeuticArea":"Oncology","highestDevelopmentStatus":"Preclinical","country":"GERMANY","productType":"Large molecule","productStatus":"New Molecular Entity","date":"May 2022","url1":"","url2":"","graph1":"Oncology","graph2":"Preclinical"},{"orgOrder":0,"company":"Tubulis","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"D","amount":"$1,022.7 million","upfrontCash":"$22.7 million","newsHeadline":"Tubulis Announces Strategic License Agreement with Bristol Myers Squibb to Develop Next Generation ADCs for the Treatment of Cancer Patients","therapeuticArea":"Oncology","highestDevelopmentStatus":"Undisclosed","country":"GERMANY","productType":"Large molecule","productStatus":"New Molecular Entity","date":"April 2023","url1":"","url2":"","graph1":"Oncology","graph2":"Undisclosed"},{"orgOrder":0,"company":"Tubulis","sponsor":"EQT Life Sciences","pharmaFlowCategory":"D","amount":"$138.8 million","upfrontCash":"Undisclosed","newsHeadline":"Tubulis Rides Wave of ADC Interest to $138M Financing Round","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase I\/ Phase II","country":"GERMANY","productType":"Large molecule","productStatus":"New Molecular Entity","date":"March 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Phase I\/ Phase II"}]

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            Development Status

            Details:

            The financing aims to support Tubulis' ongoing clinical development of TUB-040,a novel Napi2b-targeting ADC-based product. Which is being evaluated in the Phase II clinical trial studies for the treatment of Ovarian Cancer and Non-small Cell Lung Cancer.

            Lead Product(s): TUB-040

            Therapeutic Area: Oncology Product Name: TUB-040

            Highest Development Status: Phase I/ Phase II Product Type: Large molecule

            Partner/Sponsor/Collaborator: EQT Life Sciences

            Deal Size: $138.8 million Upfront Cash: Undisclosed

            Deal Type: Series B Financing March 14, 2024

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            Details:

            Through the license agreement, Bristol Myers Squibb will gain exclusive rights to access Tubulis’ Tubutecan payloads in combination with Tubulis’ proprietary P5 conjugation platform for the development of a selected number of highly differentiated ADCs to treat solid tumors.

            Lead Product(s): Antibody-drug Conjugate

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: Bristol Myers Squibb

            Deal Size: $1,022.7 million Upfront Cash: $22.7 million

            Deal Type: Licensing Agreement April 19, 2023

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            The proceeds will enable the company to deliver the true therapeutic potential of antibody drug conjugates (ADCs) through further innovation of novel payload classes and identification of new cancer targets.

            Lead Product(s): Antibody-drug Conjugate

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Andera Partners

            Deal Size: $63.0 million Upfront Cash: Undisclosed

            Deal Type: Series B Financing May 03, 2022

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            WuXi Biologics and WuXi STA will perform scale-up, process development and GMP manufacturing for the ADC product intermediates. The first program from Tubulis’ pipeline the companies will collaborate on is TUB-010.

            Lead Product(s): TUB-010

            Therapeutic Area: Oncology Product Name: TUB-010

            Highest Development Status: Preclinical Product Type: Large molecule

            Recipient: WuXi Biologics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership December 02, 2020

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            Details:

            The funds will be used to accelerate the development of a new class of highly stable and efficient antibody-drug conjugates (ADCs) and to support the further growth of the company.

            Lead Product(s): TUB-010

            Therapeutic Area: Oncology Product Name: TUB-010

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: BioMedPartners

            Deal Size: $12.5 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing July 21, 2020

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