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    [{"orgOrder":0,"company":"Trevi Therapeutics","sponsor":"Morgan Stanley","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Controlled Substance","year":"2025","type":"Public Offering","leadProduct":"Nalbuphine Hydrochloride","moa":"Opioid receptors; mu\/kappa\/delta","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase III","graph3":"Trevi Therapeutics","amount2":0.10000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0.12,"dosageForm":"Oral Tablet, Extended Release","sponsorNew":"Trevi Therapeutics \/ Morgan Stanley","highestDevelopmentStatusID":"10","companyTruncated":"Trevi Therapeutics \/ Morgan Stanley"},{"orgOrder":0,"company":"Trevi Therapeutics","sponsor":"Morgan Stanley","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Controlled Substance","year":"2025","type":"Public Offering","leadProduct":"Nalbuphine Hydrochloride","moa":"Opioid receptors; 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    Find Clinical Drug Pipeline Developments & Deals by Trevi Therapeutics

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                            01

                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Morgan Stanley

                            Deal Size : $115.1 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Trevi Therapeutics Announces Closing of $115 Million Underwritten Offering

                            Details : The Company intends to use the net proceeds for the development of Haduvio (oral nalbuphine extended-release) for the treatment of chronic cough in patients with IPF.

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            June 05, 2025

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Morgan Stanley

                            Deal Size : $115.1 million

                            Deal Type : Public Offering

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                            02

                            Trevi Therapeutics

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                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Morgan Stanley

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Trevi Therapeutics Announces Pricing of $100 Million Underwritten Offering of Common Stock

                            Details : The Company intends to use the net proceeds for the development of Haduvio (oral nalbuphine extended-release) for the treatment of chronic cough in patients with IPF.

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            June 03, 2025

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Morgan Stanley

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            03

                            Trevi Therapeutics

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                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Trevi Reports Positive Phase 2a Data for Haduvio in Chronic Cough

                            Details : Haduvio (nalbuphine) is a centrally and peripherally acting investigational therapy which is under development for the treatment of patients with refractory chronic cough.

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            March 10, 2025

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Trevi Therapeutics

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                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Trevi Completes Enrollment for Haduvio Phase 2b in IPF

                            Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under development for the treatment of idiopathic pulmonary fibrosis patients with chronic cough.

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            February 25, 2025

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Trevi Therapeutics

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                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Adage Capital Partners

                            Deal Size : $50.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Trevi Therapeutics Announces Pricing of $50 Million Underwritten Offering

                            Details : The net proceeds will be used to fund the clinical development of company's lead product Haduvio (nalbuphine) for the treatment of Chronic Cough in Idiopathic Pulmonary Fibrosis.

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            December 16, 2024

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Adage Capital Partners

                            Deal Size : $50.0 million

                            Deal Type : Public Offering

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                            06

                            Trevi Therapeutics

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                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Trevi Finds Positive Human Abuse Potential Data for Oral Nalbuphine Therapy

                            Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under phase 2 clinical development for the treatment of refractory chronic cough (RCC).

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            December 03, 2024

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Trevi Therapeutics

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                            Pharmaconex
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                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Trevi Completes Phase 2a RIVER Trial Enrollment for Chronic Cough

                            Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under development for the treatment of chronic cough in idiopathic pulmonary fibrosis.

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            October 21, 2024

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Trevi Therapeutics

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                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Refractory Chronic Cough Improvement Via NAL ER (RIVER)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 27, 2023

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cough Reduction in IPF With Nalbuphine ER

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 27, 2023

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Trevi Therapeutics

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                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Trevi Therapeutics Announces the Initiation of its Phase 2a RIVER Clinical Trial of Haduvio™ for Refractory ...

                            Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under phase 2 clinical development for the treatment of refractory chronic cough (RCC).

                            Product Name : Haduvio

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            February 11, 2023

                            Lead Product(s) : Nalbuphine Hydrochloride

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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