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                          Therapeutic Area by Lead Product

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                          01

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : TRX-100 (tivoxavir marboxil) is an inhibitor of highly conserved influenza protein, CAP-dependent endonuclease (CEN). It has demonstrated potent activity against highly pathogenic influenza strains.

                          Product Name : TRX100

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 03, 2025

                          Lead Product(s) : Tivoxavir Marboxil

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : TRX-100 (tivoxavir marboxil) is an inhibitor of highly conserved influenza protein, CAP-dependent endonuclease (CEN). It has demonstrated potent activity against highly pathogenic influenza strains.

                          Product Name : TRX100

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 23, 2025

                          Lead Product(s) : Tivoxavir Marboxil

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : TRX-100 (tivoxavir marboxil) is an inhibitor of highly conserved influenza protein, CAP-dependent endonuclease (CEN). It has demonstrated potent activity against highly pathogenic influenza strains.

                          Product Name : TRX100

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 23, 2024

                          Lead Product(s) : Tivoxavir Marboxil

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : Trwas Pharma's lead product TRX01 (ratutrelvir) is an orally-available protease inhibitor, which is being evaluated for the of treatment COVID19.

                          Product Name : TRX01

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 30, 2024

                          Lead Product(s) : Travatrelvir

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : TRX01(travatrelvir) is an inhibitor targeting the SARS-CoV-2 viral main protease (MPro/3CL). It is being developed for the treatment of Covid 19.

                          Product Name : TRX01

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 05, 2024

                          Lead Product(s) : Travatrelvir

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : Through the merger, the company will focus on the clinical development of TRX100 (viroksavir), a CEN inhibitor. Currently, it is being evaluated in the Phase I clinical trial studies for influenza.

                          Product Name : TRX100

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 04, 2024

                          Lead Product(s) : Tivoxavir Marboxil

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Onconova Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          07

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : The net proceeds will be used in the clinical development of TRX100 (viroksavir), a CEN inhibitor. Currently, it is being evaluating in the Phase I clinical trial studies for influenza.

                          Product Name : TRX100

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 04, 2024

                          Lead Product(s) : Tivoxavir Marboxil

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : OrbiMed Advisors

                          Deal Size : $28.0 million

                          Deal Type : Private Placement

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