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    [{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Bukwang Pharmaceutical Co., Ltd","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Endocrinology","graph2":"Phase II","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Melior Pharmaceuticals \/ Bukwang Pharmaceutical Co., Ltd","highestDevelopmentStatusID":"8","companyTruncated":"Melior Pharmaceuticals \/ Bukwang Pharmaceutical Co., Ltd"},{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Bukwang Pharmaceutical Co., Ltd","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Endocrinology","graph2":"Phase II","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Melior Pharmaceuticals \/ Bukwang Pharmaceutical Co., Ltd","highestDevelopmentStatusID":"8","companyTruncated":"Melior Pharmaceuticals \/ Bukwang Pharmaceutical Co., Ltd"},{"orgOrder":0,"company":"Biodexa Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Endocrinology","graph2":"Phase I","graph3":"Biodexa Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Biodexa Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Biodexa Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Biodexa Pharmaceuticals","sponsor":"Ladenburg Thalmann & Co","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2023","type":"Public Offering","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Endocrinology","graph2":"Phase I","graph3":"Biodexa Pharmaceuticals","amount2":0.01,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0.01,"dosageForm":"Tablet","sponsorNew":"Biodexa Pharmaceuticals \/ Ladenburg Thalmann & Co","highestDevelopmentStatusID":"6","companyTruncated":"Biodexa Pharmaceuticals \/ Ladenburg Thalmann & Co"},{"orgOrder":0,"company":"Adhera Therapeutics","sponsor":"Biodexa Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Licensing Agreement","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Endocrinology","graph2":"Phase I","graph3":"Adhera Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Adhera Therapeutics \/ Biodexa Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Adhera Therapeutics \/ Biodexa Pharmaceuticals"},{"orgOrder":0,"company":"Adhera Therapeutics","sponsor":"Melior Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Licensing Agreement","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Endocrinology","graph2":"Phase I","graph3":"Adhera Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Adhera Therapeutics \/ Melior Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Adhera Therapeutics \/ Melior Pharmaceuticals"},{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Melior Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"Melior Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Commonwealth Of Pennsylvania\u2019S Covid-19 Vaccines","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Funding","leadProduct":"Tolimidone","moa":"Tyrosine-protein kinase Lyn","graph1":"Immunology","graph2":"Preclinical","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Melior Pharmaceuticals \/ Commonwealth Of Pennsylvania\u2019S Covid-19 Vaccines","highestDevelopmentStatusID":"4","companyTruncated":"Melior Pharmaceuticals \/ Commonwealth Of Pennsylvania\u2019S Covid-19 Vaccines"}]

    Find Clinical Drug Pipeline Developments & Deals for Tolimidone

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                            01

                            Biodexa Pharmaceuticals

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                            Biodexa Pharmaceuticals

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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Biodexa Announces Health Canada Approval for Phase 2a Tolimidone in Type 1 Diabetes

                            Details : MLR-1023 (tolimidone), a selective activator of the enzyme lyn kinase which increases phosphorylation of insulin substrate 1, being developed for the treatment of type 1 diabetes.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 16, 2024

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Biodexa Pharmaceuticals

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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Ladenburg Thalmann & Co

                            Deal Size : $6.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Biodexa Announces Closing Of $6.0 Million Underwritten Public Offering, Including Full Exercise Of Overallotme...

                            Details : The net proceeds will be used to advance the development of MLR-1023 (tolimidone), a selective activator of the enzyme lyn kinase which increases phosphorylation of insulin substrate 1, being developed for the treatment of type 1 diabetes.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            December 21, 2023

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Ladenburg Thalmann & Co

                            Deal Size : $6.0 million

                            Deal Type : Public Offering

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                            03

                            Adhera Therapeutics

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                            AIChE Annual Meeting
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                            Adhera Therapeutics

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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Biodexa Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Biodexa Enters into Agreements to Acquire Exclusive Worldwide License to Tolimidone, a Phase II Ready Asset fo...

                            Details : Under the agreement, Biodexa gain rights to develop and commercialize MLR-1023 (tolimidone), a selective activator of the enzyme lyn kinase and Phase II Ready Asset for Type 1 Diabetes.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            November 27, 2023

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Biodexa Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            04

                            Adhera Therapeutics

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                            Adhera Therapeutics

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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Sponsor : Melior Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Adhera Inks Exclusive License Agreement with Melior Pharmaceuticals for MLR-1023

                            Details : Adhera will license MLR-1023 (tolimidone) from Melior Pharma 1 for the purpose of developing a novel therapeutic for Type 1 diabetes. MLR-1023, a lyn kinase activator, which has shown exceptional clinical safety and tolerability in Phase 2a and Phase 2b ...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            August 24, 2021

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Sponsor : Melior Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            05

                            Melior Pharmaceuticals

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                            AIChE Annual Meeting
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                            Melior Pharmaceuticals

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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Melior Pharmaceuticals Receives IND Clearance from US FDA for COVID-19 Therapeutic

                            Details : The planned Phase 2 study is intended to recruit 236 subjects who were recently diagnosed with COVID-19, have early symptoms, but are not hospitalized. Tolimidone will be taken as an orally administered pill once a day.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 09, 2021

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Melior Pharmaceuticals

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                            Melior Pharmaceuticals

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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Commonwealth Of Pennsylvania’S Covid-19 Vaccines

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Melior Pharmaceuticals Awarded Grant for Advancing Pulmonary Therapeutic in COVID-19 Phase 2 Clinical Trial

                            Details : The Phase 2 clinical trial is intended to test tolimidone in subjects who were recently diagnosed with COVID19, but are not hospitalized. Tolimidone is expected to mitigate the probability and severity of COVID-19 subjects developing severe lung complica...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 15, 2020

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Commonwealth Of Pennsylvania’S Covid-19 Vaccines

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            07

                            Melior Pharmaceuticals

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                            AIChE Annual Meeting
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                            Melior Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            An Add-on Study of MLR-1023 in Adults With Uncontrolled Type 2 Diabetes on Metformin Therapy

                            Details : MLR-1023 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Diabetes Mellitus, Type 2.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 12, 2017

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Melior Pharmaceuticals

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                            Melior Pharmaceuticals

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                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Adult Subjects With Uncontrolled Type 2 Diabetes

                            Details : MLR-1023 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Diabetes Mellitus, Type 2.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 16, 2014

                            Lead Product(s) : Tolimidone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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