
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Renova Health
Deal Size : Inapplicable
Deal Type : Inapplicable
TNF & Renova Show Targeting Potential for Inflammation with GLP-1 Therapy
Details : The study series is expected to evaluate the impact of the Company’s novel oral TNF-alpha inhibitor, MYMD-1 (isomyosamine), in preserving lean muscle mass during and after GLP-1 treatment.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 08, 2025
Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Renova Health
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Isomyosamine is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Sarcopenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 24, 2025
Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isomyosamine
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
TNF Pharmaceuticals Initiates Phase 2b Clinical Trial of First Oral TNF-Alpha Inhibitor
Details : MYMD-1 (isomyosamine) is an oral TNF-alpha inhibitor drug, currently being investigated in patients with chronic inflammation associated with sarcopenia/frailty.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 25, 2025
Lead Product(s) : Isomyosamine
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isomyosamine
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
TNF Studies Lean Muscle Preservation in GLP-1 Weight Loss Therapy
Details : MYMD-1 (isomyosamine) is a TNF-alpha inhibitor drug, currently being investigated in lean muscle mass during and after GLP-1 treatment for weight loss and chronic weight management.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 29, 2025
Lead Product(s) : Isomyosamine
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
TNF Pharmaceuticals Announces Positive Clinical Data Supporting Clinical Trial Expansion
Details : MYMD-1 (isomyosamine) is a TNF-alpha inhibitor drug, currently being investigated in patients with sarcopenia/frailty.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 15, 2025
Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Renova Health
Deal Size : Undisclosed
Deal Type : Agreement
TNF Pharmaceuticals Explores Sarcopenia Therapy Linked to GLP-1 Weight Loss Drugs
Details : Under the agreement, TNF will advance the MYMD-1 (isomyosamine) a TNF-α inhibitor. It is being evaluated in mid-stage studies for the treatment of Sarcopenia and frailty.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 19, 2024
Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Renova Health
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Prevail Partners
Deal Size : Undisclosed
Deal Type : Financing
TNF Pharmaceuticals Announces Strategic Equity Investment Priced at a Premium to Market
Details : The proceeds will provide clinical services for the next Phase 2 clinical study using company's proprietary drug, MYMD-1, a novel, orally dosed TNFα inhibitor, in sarcopenia/frailty.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 02, 2024
Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Prevail Partners
Deal Size : Undisclosed
Deal Type : Financing

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Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
TNF Pharmaceuticals Advances Lead Program For Age-Related Decline
Details : MYMD-1 is a small molecule shown to block excessive activity of TNF-alpha (TNF-α) in the blood to regulate the immuno-metabolic system. It is being evaluated for treatment of Sarcopenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 21, 2024
Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MYMD-1 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Sarcopenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 17, 2022
Lead Product(s) : Isomyosamine
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Isomyosamine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MYMD-1 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hashimoto Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 14, 2021
Lead Product(s) : Isomyosamine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
