[{"orgOrder":0,"company":"The Progeria Research Foundation","sponsor":"Eiger BioPharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Divestment","leadProduct":"Lonafarnib","moa":"||Ftase","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"The Progeria Research Foundation","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"The Progeria Research Foundation \/ The Progeria Research Foundation","highestDevelopmentStatusID":"15","companyTruncated":"The Progeria Research Foundation \/ The Progeria Research Foundation"},{"orgOrder":0,"company":"The Progeria Research Foundation","sponsor":"Eiger BioPharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Lonafarnib","moa":"||Ftase","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"The Progeria Research Foundation","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"The Progeria Research Foundation \/ The Progeria Research Foundation","highestDevelopmentStatusID":"15","companyTruncated":"The Progeria Research Foundation \/ The Progeria Research Foundation"}]

Find Clinical Drug Pipeline Developments & Deals by The Progeria Research Foundation

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                          Top Deals by Deal Size (USD bn)

                          01

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Zokinvy® (lonafarnib), is a first-in-class disease-modifying agent that blocks the accumulation of defective progerin and progerin-like proteins which leads to cellular instability and premature aging in children and young adults with progeria.

                          Product Name : Zokinvy

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 20, 2022

                          Lead Product(s) : Lonafarnib,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Recipient : Eiger BioPharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The PRV was granted in conjunction with the recent approval by the U.S. Food and Drug Administration of ZokinvyTM (lonafarnib) for treatment of Progeria and processing-deficient Progeroid Laminopathies.

                          Product Name : Zokinvy

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 23, 2020

                          Lead Product(s) : Lonafarnib,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Recipient : Eiger BioPharmaceuticals

                          Deal Size : $95.0 million

                          Deal Type : Divestment

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