Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Recipient : Innoviva Specialty Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 27, 2025
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Recipient : Innoviva Specialty Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Reproxalap
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aldeyra to Present New Reproxalap Data from Phase 2 Clinical Trial in Allergic Conjunctivitis
Details : Compared to vehicle, reproxalap demonstrated statistically significant and clinically relevant improvements in subject-reported ocular itching and tearing and investigator-assessed ocular redness over the duration of exposure in the allergen chamber.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 22, 2020
Lead Product(s) : Reproxalap
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : Melinta Therapeutics
Deal Size : $55.0 million
Deal Type : Merger
Melinta Therapeutics to Acquire Tetraphase Pharmaceuticals
Details : Through this acquisition, Melinta will enhance its commercial portfolio with XERAVATM. Once the transaction closes, Melinta will have a portfolio of five complementary marketed antibiotics: VABOMERE, ORBACTIV, BAXDELA, MINOCIN for Injection, and XERAVATM...
Product Name : Xerava
Product Type : Other Small Molecule
Upfront Cash : $55.0 million
September 06, 2020
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : Melinta Therapeutics
Deal Size : $55.0 million
Deal Type : Merger
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : La Jolla Pharmaceutical
Deal Size : $59.0 million
Deal Type : Acquisition
La Jolla Pharmaceutical Company to Acquire Tetraphase Pharmaceuticals, Inc.
Details : Combined company will offer two innovative therapies to treat patients suffering from life-threatening diseases.
Product Name : Xerava
Product Type : Other Small Molecule
Upfront Cash : $43.0 million
June 24, 2020
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : La Jolla Pharmaceutical
Deal Size : $59.0 million
Deal Type : Acquisition
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : AcelRx Pharmaceuticals
Deal Size : $26.9 million
Deal Type : Acquisition
AcelRx Pharmaceuticals to Acquire Tetraphase Pharmaceuticals
Details : Tetraphase and AcelRx entered into a co-promotion agreement to market and promote XERAVA™ for the treatment of complicated intra-abdominal infections and DSUVIA® for the treatment of acute pain.
Product Name : Xerava
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 16, 2020
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : AcelRx Pharmaceuticals
Deal Size : $26.9 million
Deal Type : Acquisition
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : Armistice Capital
Deal Size : $17.5 million
Deal Type : Financing
Tetraphase Pharmaceuticals Announces $17.5 Million of Financings Priced At-the-Market
Details : The company intends to use the net proceeds from the registered direct offering and concurrent private placement for the commercialization of XERAVA as well as for working capital and other general corporate purposes.
Product Name : Xerava
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 22, 2020
Lead Product(s) : Eravacycline
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : Armistice Capital
Deal Size : $17.5 million
Deal Type : Financing
Lead Product(s) : Eravacycline Dihydrochloride
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
A Safety and PK Study of IV Eravacycline
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 04, 2018
Lead Product(s) : Eravacycline Dihydrochloride
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : TP-6076
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : PRA Health Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 1, Safety and Bronchopulmonary PK Study in Healthy Volunteers
Details : Undisclosed
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
October 02, 2018
Lead Product(s) : TP-6076
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : PRA Health Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : TP-271
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : National Institute of Allergy and Infectious Diseases
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 1 TP-271 Oral PK Multiple Ascending Dose Study
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 01, 2018
Lead Product(s) : TP-271
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : National Institute of Allergy and Infectious Diseases
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : TP-271
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : National Institute of Allergy and Infectious Diseases
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 1 Safety and PK Study of IV TP-271
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 31, 2017
Lead Product(s) : TP-271
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : National Institute of Allergy and Infectious Diseases
Deal Size : Inapplicable
Deal Type : Inapplicable