Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The overall safety profile of ANG-3777 in this trial was consistent with the overall experience in its clinical development program and consistent with the published literature in this patient population.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 26, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ANG-3777 is a small molecule designed to mimic the biological activity of hepatocyte growth factor (HGF), trial did not meet its primary endpoint of percentage increase in serum creatinine based upon the area under the curve (AUC).
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 12, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The results from the Phase 2 GUARD trial of Angion’s ANG-3777 in patients undergoing cardiac surgery involving cardiopulmonary bypass at risk for developing acute kidney injury.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 12, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Nucleus Network
Deal Size : Inapplicable
Deal Type : Inapplicable
Study to Evaluate the Pharmacokinetics of ANG-3777 in Hemodialysis Subjects
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 12, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Nucleus Network
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Quotient Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 24, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Quotient Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : $30.0 million
Deal Type : Licensing Agreement
Vifor Pharma and Angion Sign License Agreement for ANG-3777 in Nephrology Indications
Details : Under the terms of the agreement, Vifor Pharma will receive an exclusive global license, excluding China, Taiwan, Hong Kong and Macau, for all ANG-3777 nephrology indications.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : $30.0 million
September 11, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : $30.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Terevalefim
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The Phase 2 trial is a multicenter, prospective, randomized, double-blind, placebo-controlled trial to assess safety and efficacy of ANG-3777 in patients hospitalized with confirmed COVID-19 pneumonia.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 07, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : CTI Clinical Trial and Consulting
Deal Size : Inapplicable
Deal Type : Inapplicable
Study to Assess Efficacy and Safety Relative to Standard of Care in Patients With COVID-19 Pneumonia
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 07, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : CTI Clinical Trial and Consulting
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The Company is going to discuss the effect of ANG-3777 on Hepatocyte Growth Factor Receptor c-MET Signaling.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 29, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable
Angion Announces Publication of ANG-3777 Phase 2 Results in the Scientific Journal Transplantation
Details : The publication details the results of the administration of ANG-3777 in patients who have undergone deceased-donor kidney transplantation and had signs of kidney injury.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 05, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : CSL Vifor
Deal Size : Inapplicable
Deal Type : Inapplicable