[{"orgOrder":0,"company":"NIHR","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"NIHR","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"NIHR \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"NIHR \/ Undisclosed"},{"orgOrder":0,"company":"U.S. Army Medical Research and Development Command","sponsor":"SIGA Technologies","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and 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Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"SIGA Technologies \/ US Department of Defense","highestDevelopmentStatusID":"15","companyTruncated":"SIGA Technologies \/ US Department of Defense"},{"orgOrder":0,"company":"National Institute of Allergy and Infectious Diseases","sponsor":"SIGA Technologies","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"National Institute of Allergy and Infectious Diseases","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"National Institute of Allergy and Infectious Diseases \/ SIGA Technologies","highestDevelopmentStatusID":"10","companyTruncated":"National Institute of Allergy and Infectious Diseases \/ SIGA Technologies"},{"orgOrder":0,"company":"SIGA Technologies","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"SIGA Technologies","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"SIGA Technologies \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"SIGA Technologies \/ Undisclosed"},{"orgOrder":0,"company":"Meridian Medical Technologies","sponsor":"SIGA Technologies","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious 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Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Funding","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"SIGA Technologies","amount2":0.01,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.01,"dosageForm":"Capsule","sponsorNew":"SIGA Technologies \/ US Department of Defense","highestDevelopmentStatusID":"15","companyTruncated":"SIGA Technologies \/ US Department of Defense"},{"orgOrder":0,"company":"SIGA Technologies","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"SIGA Technologies","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"SIGA Technologies \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"SIGA Technologies \/ Undisclosed"},{"orgOrder":0,"company":"SIGA Technologies","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"SIGA Technologies","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"SIGA Technologies \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"SIGA Technologies \/ Undisclosed"},{"orgOrder":0,"company":"Meridian Medical Technologies","sponsor":"Public Health Agency of Canada","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Collaboration","leadProduct":"Tecovirimat","moa":"Envelope phospholipase OPG057","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Meridian Medical Technologies","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Meridian Medical Technologies \/ Public Health Agency of Canada","highestDevelopmentStatusID":"15","companyTruncated":"Meridian Medical Technologies \/ Public Health Agency of Canada"},{"orgOrder":0,"company":"SIGA Technologies","sponsor":"ASEAN","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious 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                          01

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Tepoxx (tecovirimat) is an oral orthopoxvirus VP37 envelope-wrapping protein inhibitor, Currently, it is being evaluated in the mid-stage clinical trial for the treatment of Orthopoxviruses.

                          Product Name : Tepoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 02, 2025

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Tpoxx (tecovirimat) is an antiviral drug candidate that targets orthopoxvirus VP37 envelope wrapping protein. It is being evaluated for the treatment of mpox.

                          Product Name : Tpoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 10, 2024

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The agreement aims for the procurement of Tpoxx (tecovirimat), an antiviral, approved in the US and Canada for the treatment of smallpox and authorized in EU and the UK for smallpox, mpox and cowpox.

                          Product Name : Tpoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          August 21, 2024

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : US Department of Defense

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Tpoxx (tecovirimat) is an oral orthopoxvirus VP37 envelope-wrapping protein inhibitor, Currently, it is being evaluated in the mid-stage clinical trial for the treatment of Monkeypox Virus.

                          Product Name : Tpoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 15, 2024

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The agreement aims to expand access to Tpoxx (tecovirimat), a novel small-molecule drug for the treatment of smallpox, to the member states in the ASEAN.

                          Product Name : Tpoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          June 17, 2024

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : ASEAN

                          Deal Size : Undisclosed

                          Deal Type : Divestment

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : SIGA will lead international promotions for oral TPOXX, an FDA-approved drug for smallpox, while maintaining its contractual relationship with Meridian to ensure continuity for key customers.

                          Product Name : Tpoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          April 01, 2024

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : SIGA Technologies

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : TPOXX (tecovirimat), also known as tecovirimat and ST-246®, an orally administered and IV formulation antiviral drug for the treatment of human smallpox disease caused by variola virus.

                          Product Name : Tpoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 12, 2022

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Tecovirimat is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Mpox, Monkeypox.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 10, 2022

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : SIGA Technologies

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Marina Klein

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Marina Klein

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase III

                          Sponsor : McGill University Health Centre Research Institute | University Health Network, Toronto | Unity Health Toronto | University of British Columbia | CIHR Canadian HIV Trials Network

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Tecovirimat is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Mpox, Monkeypox.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 09, 2022

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : McGill University Health Centre Research Institute | University Health Network, Toronto | Unity Health Toronto | University of British Columbia | CIHR Canadian HIV Trials Network

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          NIHR

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          NIHR

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Tecovirimat (also known as TPOXX®) prevents the virus from leaving infected cells, stopping its spread within the body for monkeypox based on promising results from initial studies in animals and evidence of safety in healthy human volunteers.

                          Product Name : Tpoxx

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 23, 2022

                          Lead Product(s) : Tecovirimat

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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